8a28 - Revision history

OCA at 14:19, 6 November 2024

2024-11-06T14:19:27Z

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 == Function ==
 [https://www.uniprot.org/uniprot/B4F320_LIMPO B4F320_LIMPO] Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.[ARBA:ARBA00025529]
 __TOC__
 </StructureSection>

OCA at 10:55, 27 March 2024

2024-03-27T10:55:03Z

← Older revision		Revision as of 10:55, 27 March 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8a28]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Limulus_polyphemus Limulus polyphemus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A28 FirstGlance]. <br>		<table><tr><td colspan='2'>[[8a28]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Limulus_polyphemus Limulus polyphemus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A28 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a28 OCA], [https://pdbe.org/8a28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a28 RCSB], [https://www.ebi.ac.uk/pdbsum/8a28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a28 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a28 OCA], [https://pdbe.org/8a28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a28 RCSB], [https://www.ebi.ac.uk/pdbsum/8a28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a28 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 19:25, 19 October 2022

2022-10-19T19:25:57Z

← Older revision		Revision as of 19:25, 19 October 2022
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	~~'''Unreleased structure'''~~

	~~The entry~~ 8a28 is ~~ON HOLD until Paper Publication~~		==Structure of the astacin zymogen of LAST-MAM from Limulus polyphemus==
			<StructureSection load='8a28' size='340' side='right'caption='[[8a28]], [[Resolution\|resolution]] 2.40Å' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>[[8a28]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Limulus_polyphemus Limulus polyphemus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A28 FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	[[Category: ~~Unreleased~~ Structures]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a28 OCA], [https://pdbe.org/8a28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a28 RCSB], [https://www.ebi.ac.uk/pdbsum/8a28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a28 ProSAT]</span></td></tr>
			</table>
			== Function ==
			[https://www.uniprot.org/uniprot/B4F320_LIMPO B4F320_LIMPO] Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.[ARBA:ARBA00025529]
			__TOC__
			</StructureSection>
			[[Category: Large Structures]]
			[[Category: Limulus polyphemus]]
			[[Category: Guevara T]]
			[[Category: Rodriguez Banqueri A]]

OCA at 04:05, 15 June 2022

2022-06-15T04:05:18Z

← Older revision		Revision as of 04:05, 15 June 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 8a28 is ON HOLD		The entry 8a28 is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8a28" [edit=sysop:move=sysop]

2022-06-08T04:24:19Z

Protected "8a28" [edit=sysop:move=sysop]

← Older revision	Revision as of 04:24, 8 June 2022
(No difference)

OCA: New page: '''Unreleased structure''' The entry 8a28 is ON HOLD Authors: Description: Category: Unreleased Structures

2022-06-08T04:24:18Z

New page: '''Unreleased structure''' The entry 8a28 is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8a28 is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]