8bpp - Revision history

OCA at 09:26, 4 March 2026

2026-03-04T09:26:17Z

← Older revision		Revision as of 09:26, 4 March 2026
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	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/NEMA_ECOLI NEMA_ECOLI] Involved in the degradation of toxic compounds (PubMed:~~9013822~~, PubMed:~~15184158~~, PubMed:~~17504490~~, PubMed:23527133, PubMed:~~23506073~~, PubMed:~~23536188~~). Can use a variety of substrates, including the nitrate ester explosives glycerol trinitrate (GTN) and pentaerythritol tetranitrate (PETN), chromate and various electrophiles such as quinones (PubMed:15184158, PubMed:~~23527133~~, PubMed:~~23506073~~). Involved in resistance to hypochlorous acid (HOCl), which is the active component of household bleach and a powerful antimicrobial during the innate immune response (PubMed:23536188). Catalyzes the reduction of N-ethylmaleimide (NEM) to N-ethylsuccinimide (PubMed:~~9013822~~, PubMed:~~23506073~~). Together with NfsA and NfsB, can use the nitroaromatic explosive 2,4,6-trinitrotoluene (TNT) (PubMed:17504490).<ref>PMID:15184158</ref> <ref>PMID:17504490</ref> <ref>PMID:23506073</ref> <ref>PMID:23527133</ref> <ref>PMID:23536188</ref> <ref>PMID:9013822</ref>		[https://www.uniprot.org/uniprot/NEMA_ECOLI NEMA_ECOLI] Involved in the degradation of toxic compounds (PubMed:15184158, PubMed:17504490, PubMed:23506073, PubMed:23527133, PubMed:23536188, PubMed:9013822). Can use a variety of substrates, including the nitrate ester explosives glycerol trinitrate (GTN) and pentaerythritol tetranitrate (PETN), chromate and various electrophiles such as quinones (PubMed:15184158, PubMed:23506073, PubMed:23527133). Involved in resistance to hypochlorous acid (HOCl), which is the active component of household bleach and a powerful antimicrobial during the innate immune response (PubMed:23536188). Catalyzes the reduction of N-ethylmaleimide (NEM) to N-ethylsuccinimide (PubMed:23506073, PubMed:9013822). Together with NfsA and NfsB, can use the nitroaromatic explosive 2,4,6-trinitrotoluene (TNT) (PubMed:17504490).<ref>PMID:15184158</ref> <ref>PMID:17504490</ref> <ref>PMID:23506073</ref> <ref>PMID:23527133</ref> <ref>PMID:23536188</ref> <ref>PMID:9013822</ref>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:34, 1 March 2024

2024-03-01T09:34:19Z

← Older revision		Revision as of 09:34, 1 March 2024
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	~~'''Unreleased structure'''~~

	~~The entry~~ 8bpp is ~~ON HOLD until Paper Publication~~		==crystal structure of N-ethylmaleimide reductase (nemA) from Escherichia coli==
			<StructureSection load='8bpp' size='340' side='right'caption='[[8bpp]], [[Resolution\|resolution]] 3.10Å' scene=''>
	~~Authors~~:		== Structural highlights ==
			<table><tr><td colspan='2'>[[8bpp]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BPP FirstGlance]. <br>
	~~Description~~:		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.1Å</td></tr>
	[[Category: ~~Unreleased~~ Structures]]		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bpp OCA], [https://pdbe.org/8bpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bpp RCSB], [https://www.ebi.ac.uk/pdbsum/8bpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bpp ProSAT]</span></td></tr>
			</table>
			== Function ==
			[https://www.uniprot.org/uniprot/NEMA_ECOLI NEMA_ECOLI] Involved in the degradation of toxic compounds (PubMed:9013822, PubMed:15184158, PubMed:17504490, PubMed:23527133, PubMed:23506073, PubMed:23536188). Can use a variety of substrates, including the nitrate ester explosives glycerol trinitrate (GTN) and pentaerythritol tetranitrate (PETN), chromate and various electrophiles such as quinones (PubMed:15184158, PubMed:23527133, PubMed:23506073). Involved in resistance to hypochlorous acid (HOCl), which is the active component of household bleach and a powerful antimicrobial during the innate immune response (PubMed:23536188). Catalyzes the reduction of N-ethylmaleimide (NEM) to N-ethylsuccinimide (PubMed:9013822, PubMed:23506073). Together with NfsA and NfsB, can use the nitroaromatic explosive 2,4,6-trinitrotoluene (TNT) (PubMed:17504490).<ref>PMID:15184158</ref> <ref>PMID:17504490</ref> <ref>PMID:23506073</ref> <ref>PMID:23527133</ref> <ref>PMID:23536188</ref> <ref>PMID:9013822</ref>
			== References ==
			<references/>
			__TOC__
			</StructureSection>
			[[Category: Escherichia coli]]
			[[Category: Large Structures]]
			[[Category: Erb T]]
			[[Category: Pfister P]]
			[[Category: Tinzl M]]

OCA at 05:26, 28 December 2022

2022-12-28T05:26:40Z

← Older revision		Revision as of 05:26, 28 December 2022
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 8bpp is ON HOLD		The entry 8bpp is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8bpp" [edit=sysop:move=sysop]

2022-11-24T08:05:51Z

Protected "8bpp" [edit=sysop:move=sysop]

← Older revision	Revision as of 08:05, 24 November 2022
(No difference)

OCA: New page: '''Unreleased structure''' The entry 8bpp is ON HOLD Authors: Description: Category: Unreleased Structures

2022-11-24T08:05:50Z

New page: '''Unreleased structure''' The entry 8bpp is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8bpp is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]