8seq - Revision history

OCA at 07:40, 21 November 2024

2024-11-21T07:40:00Z

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 == Function ==
 [https://www.uniprot.org/uniprot/RYR1_RABIT RYR1_RABIT] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm. Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity).<ref>PMID:10388749</ref> <ref>PMID:22036948</ref>
 == References ==
 <references/>

OCA at 06:24, 19 July 2023

2023-07-19T06:24:16Z

← Older revision		Revision as of 06:24, 19 July 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[8seq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SEQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[8seq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SEQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.4Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8seq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8seq OCA], [https://pdbe.org/8seq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8seq RCSB], [https://www.ebi.ac.uk/pdbsum/8seq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8seq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8seq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8seq OCA], [https://pdbe.org/8seq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8seq RCSB], [https://www.ebi.ac.uk/pdbsum/8seq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8seq ProSAT]</span></td></tr>
	</table>		</table>

OCA at 04:09, 25 May 2023

2023-05-25T04:09:32Z

@@ Line 1: / Line 1: @@
-The entry 8seq is ON HOLD  until Paper Publication
+==Cryo-EM Structure of RyR1 + AMP==
+<StructureSection load='8seq' size='340' side='right'caption='[[8seq]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8seq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SEQ FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8seq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8seq OCA], [https://pdbe.org/8seq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8seq RCSB], [https://www.ebi.ac.uk/pdbsum/8seq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8seq ProSAT]</span></td></tr>

OCA at 05:48, 18 May 2023

2023-05-18T05:48:23Z

← Older revision		Revision as of 05:48, 18 May 2023
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 8seq is ON HOLD		The entry 8seq is ON HOLD until Paper Publication

	Authors:		Authors:

OCA: Protected "8seq" [edit=sysop:move=sysop]

2023-04-19T08:17:29Z

Protected "8seq" [edit=sysop:move=sysop]

← Older revision	Revision as of 08:17, 19 April 2023
(No difference)

OCA: New page: '''Unreleased structure''' The entry 8seq is ON HOLD Authors: Description: Category: Unreleased Structures

2023-04-19T08:17:28Z

New page: '''Unreleased structure''' The entry 8seq is ON HOLD Authors: Description: Category: Unreleased Structures

New page

'''Unreleased structure'''

The entry 8seq is ON HOLD

Authors:

Description:
[[Category: Unreleased Structures]]