https://proteopedia.org/index.php?action=history&feed=atom&title=8ttp 8ttp - Revision history 2026-10-03T05:41:47Z Revision history for this page on the wiki MediaWiki 1.43.8 https://proteopedia.org/index.php?title=8ttp&diff=3861803&oldid=prev OCA at 06:28, 6 September 2023 2023-09-06T06:28:55Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 06:28, 6 September 2023</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">'''Unreleased structure'''</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">The entry </del>8ttp is <del style="font-weight: bold; text-decoration: none;">ON HOLD </del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">==Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam==</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;StructureSection load='8ttp' size='340' side='right'caption='[[8ttp]], [[Resolution|resolution]] 1.43&amp;Aring;' scene=''&gt;</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Authors</del>: <del style="font-weight: bold; text-decoration: none;">Chang</del>, <del style="font-weight: bold; text-decoration: none;">C.</del>, <del style="font-weight: bold; text-decoration: none;">Maltseva</del>, <del style="font-weight: bold; text-decoration: none;">N</del>., <del style="font-weight: bold; text-decoration: none;">Endres</del>, <del style="font-weight: bold; text-decoration: none;">M</del>., <del style="font-weight: bold; text-decoration: none;">Joachimiak</del>, <del style="font-weight: bold; text-decoration: none;">A</del>., <del style="font-weight: bold; text-decoration: none;">Center for Structural Biology of Infectious Diseases (CSBID)</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Structural highlights ==</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;table&gt;&lt;tr&gt;&lt;td colspan='2'&gt;[[</ins>8ttp<ins style="font-weight: bold; text-decoration: none;">]] </ins>is <ins style="font-weight: bold; text-decoration: none;">a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_A35218R Escherichia coli A35218R]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TTP OCA]. For a &lt;b&gt;guided tour on the structure components&lt;/b&gt; use [https://proteopedia.org/fgij/fg.htm?mol=8TTP FirstGlance]. &lt;br&gt;</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Description</del>: <del style="font-weight: bold; text-decoration: none;">Crystal structure of class C </del>beta-lactamase <del style="font-weight: bold; text-decoration: none;">from Escherichia coli in complex </del>with <del style="font-weight: bold; text-decoration: none;">avibactam</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/td&gt;&lt;/tr&gt;&lt;tr id='method'&gt;&lt;td class="sblockLbl"&gt;&lt;b&gt;[[Empirical_models|Method:]]&lt;/b&gt;&lt;/td&gt;&lt;td class="sblockDat" id="methodDat"&gt;X-ray diffraction, [[Resolution|Resolution]] 1.43&amp;#8491;&lt;/td&gt;&lt;/tr&gt;</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <del style="font-weight: bold; text-decoration: none;">Unreleased Structures</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;tr id='ligand'&gt;&lt;td class="sblockLbl"&gt;&lt;b&gt;[[Ligand|Ligands</ins>:<ins style="font-weight: bold; text-decoration: none;">]]&lt;/b&gt;&lt;/td&gt;&lt;td class="sblockDat" id="ligandDat"&gt;&lt;scene name='pdbligand=EDO:1,2-ETHANEDIOL'&gt;EDO&lt;/scene&gt;, &lt;scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'&gt;IPA&lt;/scene&gt;</ins>, <ins style="font-weight: bold; text-decoration: none;">&lt;scene name='pdbligand=NXL:(2S</ins>,<ins style="font-weight: bold; text-decoration: none;">5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'&gt;NXL&lt;/scene&gt;</ins>, <ins style="font-weight: bold; text-decoration: none;">&lt;scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'&gt;PEG&lt;/scene&gt;&lt;/td&gt;&lt;/tr&gt;</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <del style="font-weight: bold; text-decoration: none;">Maltseva, N</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;tr id='resources'&gt;&lt;td class="sblockLbl"&gt;&lt;b&gt;Resources:&lt;/b&gt;&lt;/td&gt;&lt;td class="sblockDat"&gt;&lt;span class='plainlinks'&gt;[https://proteopedia.org/fgij/fg</ins>.<ins style="font-weight: bold; text-decoration: none;">htm?mol=8ttp FirstGlance]</ins>, <ins style="font-weight: bold; text-decoration: none;">[http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ttp OCA]</ins>, <ins style="font-weight: bold; text-decoration: none;">[https://pdbe</ins>.<ins style="font-weight: bold; text-decoration: none;">org/8ttp PDBe]</ins>, <ins style="font-weight: bold; text-decoration: none;">[https://www.rcsb.org/pdb/explore.do?structureId=8ttp RCSB]</ins>, <ins style="font-weight: bold; text-decoration: none;">[https://www.ebi.ac</ins>.<ins style="font-weight: bold; text-decoration: none;">uk/pdbsum/8ttp PDBsum]</ins>, <ins style="font-weight: bold; text-decoration: none;">[https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ttp ProSAT]&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <del style="font-weight: bold; text-decoration: none;">Center For Structural Biology Of Infectious Diseases (Csbid)</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/table&gt;</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <del style="font-weight: bold; text-decoration: none;">Joachimiak, A</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Function ==</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <del style="font-weight: bold; text-decoration: none;">Chang, C</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[https</ins>:<ins style="font-weight: bold; text-decoration: none;">//www.uniprot.org/uniprot/Q104Z6_ECOLX Q104Z6_ECOLX] This protein is a serine </ins>beta-lactamase with <ins style="font-weight: bold; text-decoration: none;">a substrate specificity for cephalosporins.[ARBA:ARBA00003808]</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <del style="font-weight: bold; text-decoration: none;">Endres, M</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__TOC__</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/StructureSection&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <ins style="font-weight: bold; text-decoration: none;">Escherichia coli A35218R</ins>]]</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <ins style="font-weight: bold; text-decoration: none;">Large Structures</ins>]]</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <ins style="font-weight: bold; text-decoration: none;">Chang C</ins>]]</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <ins style="font-weight: bold; text-decoration: none;">Endres M</ins>]]</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <ins style="font-weight: bold; text-decoration: none;">Joachimiak A</ins>]]</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Category: <ins style="font-weight: bold; text-decoration: none;">Maltseva N</ins>]]</div></td></tr> </table> OCA https://proteopedia.org/index.php?title=8ttp&diff=3836858&oldid=prev OCA: Protected "8ttp" [edit=sysop:move=sysop] 2023-08-23T04:50:58Z <p>Protected &quot;<a href="/8ttp" title="8ttp">8ttp</a>&quot; [edit=sysop:move=sysop]</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <tr class="diff-title" lang="en"> <td colspan="1" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="1" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:50, 23 August 2023</td> </tr><tr><td colspan="2" class="diff-notice" lang="en"><div class="mw-diff-empty">(No difference)</div> </td></tr></table> OCA https://proteopedia.org/index.php?title=8ttp&diff=3836857&oldid=prev OCA: New page: '''Unreleased structure''' The entry 8ttp is ON HOLD Authors: Chang, C., Maltseva, N., Endres, M., Joachimiak, A., Center for Structural Biology of Infectious Diseases (CSBID) Descript... 2023-08-23T04:50:56Z <p>New page: &#039;&#039;&#039;Unreleased structure&#039;&#039;&#039; The entry 8ttp is ON HOLD Authors: Chang, C., Maltseva, N., Endres, M., Joachimiak, A., Center for Structural Biology of Infectious Diseases (CSBID) Descript...</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Unreleased structure&#039;&#039;&#039;<br /> <br /> The entry 8ttp is ON HOLD <br /> <br /> Authors: Chang, C., Maltseva, N., Endres, M., Joachimiak, A., Center for Structural Biology of Infectious Diseases (CSBID)<br /> <br /> Description: Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam<br /> [[Category: Unreleased Structures]]<br /> [[Category: Maltseva, N]]<br /> [[Category: Center For Structural Biology Of Infectious Diseases (Csbid)]]<br /> [[Category: Joachimiak, A]]<br /> [[Category: Chang, C]]<br /> [[Category: Endres, M]]</div> OCA