9dpg - Revision history

OCA at 06:15, 8 April 2026

2026-04-08T06:15:59Z

← Older revision		Revision as of 06:15, 8 April 2026
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	~~'''Unreleased structure'''~~

	~~The entry~~ 9dpg is ~~ON HOLD until Paper Publication~~		==Structure of PmHMGR bound to mevalonate, CoA and NAD 2 minutes 20 seconds after reaction initiation at pH 9==
			<StructureSection load='9dpg' size='340' side='right'caption='[[9dpg]], [[Resolution\|resolution]] 2.50Å' scene=''>
	~~Authors~~: ~~Purohit~~, V., ~~Steussy~~, C.N., ~~Schmidt~~, T., ~~Stauffacher~~, C.V., ~~Rushton, P~~.		== Structural highlights ==
			<table><tr><td colspan='2'>[[9dpg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DPG FirstGlance]. <br>
	~~Description~~: ~~Structure of PmHMGR bound~~ to ~~mevalonate,~~ CoA ~~and NAD 2 minutes 20 seconds after reaction initiation at pH 9~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
	[[Category: ~~Unreleased~~ Structures]]		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AFY:(3~{R})-3-methyl-3-oxidanyl-5-oxidanylidene-pentanoic+acid'>A1AFY</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZKE:(3~{S},5~{R})-5-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-3-methyl-3,5-bis(oxidanyl)pentanoic+acid'>ZKE</scene></td></tr>
	[[Category: ~~Steussy, C.N~~]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dpg OCA], [https://pdbe.org/9dpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dpg RCSB], [https://www.ebi.ac.uk/pdbsum/9dpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dpg ProSAT]</span></td></tr>
	[[Category: ~~Rushton, P~~]]		</table>
	[[Category: ~~Purohit, V~~]]		== Function ==
	[[Category: Schmidt, T]]		[https://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
	[[Category: Stauffacher~~, C.V~~]]		__TOC__
			</StructureSection>
			[[Category: Large Structures]]
			[[Category: Pseudomonas mevalonii]]
			[[Category: Purohit V]]
			[[Category: Rushton P]]
			[[Category: Schmidt T]]
			[[Category: Stauffacher CV]]
			[[Category: Steussy CN]]

OCA at 16:16, 7 May 2025

2025-05-07T16:16:31Z

← Older revision		Revision as of 16:16, 7 May 2025
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 9dpg is ON HOLD		The entry 9dpg is ON HOLD until Paper Publication

	Authors: Purohit, V., Steussy, C.N., Schmidt, T., Stauffacher, C.V., Rushton, P.		Authors: Purohit, V., Steussy, C.N., Schmidt, T., Stauffacher, C.V., Rushton, P.
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	Description: Structure of PmHMGR bound to mevalonate, CoA and NAD 2 minutes 20 seconds after reaction initiation at pH 9		Description: Structure of PmHMGR bound to mevalonate, CoA and NAD 2 minutes 20 seconds after reaction initiation at pH 9
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: ~~Stauffacher~~, C.V]]		[[Category: Steussy, C.N]]
	[[Category: Rushton, P]]		[[Category: Rushton, P]]
	[[Category: Purohit, V]]		[[Category: Purohit, V]]
	[[Category: Schmidt, T]]		[[Category: Schmidt, T]]
	[[Category: ~~Steussy~~, C.N]]		[[Category: Stauffacher, C.V]]

OCA at 03:00, 17 October 2024

2024-10-17T03:00:53Z

← Older revision		Revision as of 03:00, 17 October 2024
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	Authors: Purohit, V., Steussy, C.N., Schmidt, T., Stauffacher, C.V., Rushton, P.		Authors: Purohit, V., Steussy, C.N., Schmidt, T., Stauffacher, C.V., Rushton, P.

	Description: Structure of PmHMGR bound to mevalonate, CoA and NAD 4 minutes after reaction initiation at pH 9		Description: Structure of PmHMGR bound to mevalonate, CoA and NAD 2 minutes 20 seconds after reaction initiation at pH 9
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
			[[Category: Stauffacher, C.V]]
			[[Category: Rushton, P]]
	[[Category: Purohit, V]]		[[Category: Purohit, V]]
	[[Category: Schmidt, T]]		[[Category: Schmidt, T]]
	~~[[Category: Rushton, P]]~~
	~~[[Category: Stauffacher, C.V]]~~
	[[Category: Steussy, C.N]]		[[Category: Steussy, C.N]]

OCA: Protected "9dpg" [edit=sysop:move=sysop]

2024-10-05T02:53:43Z

Protected "9dpg" [edit=sysop:move=sysop]

← Older revision	Revision as of 02:53, 5 October 2024
(No difference)

OCA: New page: '''Unreleased structure''' The entry 9dpg is ON HOLD Authors: Purohit, V., Steussy, C.N., Schmidt, T., Stauffacher, C.V., Rushton, P. Description: Structure of PmHMGR bound to mevalona...

2024-10-05T02:53:42Z

New page: '''Unreleased structure''' The entry 9dpg is ON HOLD Authors: Purohit, V., Steussy, C.N., Schmidt, T., Stauffacher, C.V., Rushton, P. Description: Structure of PmHMGR bound to mevalona...

New page

'''Unreleased structure'''

The entry 9dpg is ON HOLD

Authors: Purohit, V., Steussy, C.N., Schmidt, T., Stauffacher, C.V., Rushton, P.

Description: Structure of PmHMGR bound to mevalonate, CoA and NAD 4 minutes after reaction initiation at pH 9
[[Category: Unreleased Structures]]
[[Category: Purohit, V]]
[[Category: Schmidt, T]]
[[Category: Rushton, P]]
[[Category: Stauffacher, C.V]]
[[Category: Steussy, C.N]]