9rtf - Revision history

OCA at 07:06, 15 July 2026

2026-07-15T07:06:56Z

← Older revision		Revision as of 07:06, 15 July 2026
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	~~'''Unreleased structure'''~~

	~~The entry~~ 9rtf is ~~ON HOLD until Paper Publication~~		==Crystal structure of the human serum transferrin with Fe(III) bound at the C-lobe only==
			<StructureSection load='9rtf' size='340' side='right'caption='[[9rtf]], [[Resolution\|resolution]] 2.16Å' scene=''>
	~~Authors~~: ~~Paolillo~~, M., ~~Ferraro~~, G., ~~Banneville~~, A.S., ~~Cornaciu~~, I., ~~Pica~~, A., ~~Merlino, A~~.		== Structural highlights ==
			<table><tr><td colspan='2'>[[9rtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RTF FirstGlance]. <br>
	~~Description~~: ~~Crystal structure~~ of ~~the human serum transferrin with~~ Fe(~~III~~) ~~bound at~~ the ~~C-lobe only~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.16Å</td></tr>
	[[Category: ~~Unreleased Structures~~]]		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	[[Category: ~~Paolillo, M~~]]		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rtf OCA], [https://pdbe.org/9rtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rtf RCSB], [https://www.ebi.ac.uk/pdbsum/9rtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rtf ProSAT]</span></td></tr>
	[[Category: ~~Pica, A~~]]		</table>
	[[Category: ~~Banneville, A.S~~]]		== Disease ==
	[[Category: Ferraro, G]]		[https://www.uniprot.org/uniprot/TRFE_HUMAN TRFE_HUMAN] Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:[https://omim.org/entry/209300 209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.<ref>PMID:11110675</ref> <ref>PMID:15466165</ref>
	[[Category: Merlino, A]]		== Function ==
	[[Category: ~~Cornaciu, I~~]]		[https://www.uniprot.org/uniprot/TRFE_HUMAN TRFE_HUMAN] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
			== References ==
			<references/>
			__TOC__
			</StructureSection>
			[[Category: Homo sapiens]]
			[[Category: Large Structures]]
			[[Category: Banneville AS]]
			[[Category: Cornaciu I]]
			[[Category: Ferraro G]]
			[[Category: Merlino A]]
			[[Category: Paolillo M]]
			[[Category: Pica A]]

OCA at 06:52, 13 August 2025

2025-08-13T06:52:11Z

← Older revision		Revision as of 06:52, 13 August 2025
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 9rtf is ON HOLD		The entry 9rtf is ON HOLD until Paper Publication

	Authors: Paolillo, M., Ferraro, G., Banneville, A.S., Cornaciu, I., Pica, A., Merlino, A.		Authors: Paolillo, M., Ferraro, G., Banneville, A.S., Cornaciu, I., Pica, A., Merlino, A.
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	Description: Crystal structure of the human serum transferrin with Fe(III) bound at the C-lobe only		Description: Crystal structure of the human serum transferrin with Fe(III) bound at the C-lobe only
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	~~[[Category: Merlino, A]]~~
	[[Category: Paolillo, M]]		[[Category: Paolillo, M]]
	[[Category: Pica, A]]		[[Category: Pica, A]]
			[[Category: Banneville, A.S]]
	[[Category: Ferraro, G]]		[[Category: Ferraro, G]]
	[[Category: ~~Banneville~~, A.S]]		[[Category: Merlino, A]]
	[[Category: Cornaciu, I]]		[[Category: Cornaciu, I]]

OCA at 04:33, 16 July 2025

2025-07-16T04:33:26Z

← Older revision		Revision as of 04:33, 16 July 2025
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 9rtf is ON HOLD ~~until sometime in the future~~		The entry 9rtf is ON HOLD

	Authors: Paolillo, M., Ferraro, G., Banneville, A.S., Cornaciu, I., Pica, A., Merlino, A.		Authors: Paolillo, M., Ferraro, G., Banneville, A.S., Cornaciu, I., Pica, A., Merlino, A.
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	Description: Crystal structure of the human serum transferrin with Fe(III) bound at the C-lobe only		Description: Crystal structure of the human serum transferrin with Fe(III) bound at the C-lobe only
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
			[[Category: Merlino, A]]
	[[Category: Paolillo, M]]		[[Category: Paolillo, M]]
	~~[[Category: Cornaciu, I]]~~
	[[Category: Pica, A]]		[[Category: Pica, A]]
			[[Category: Ferraro, G]]
	[[Category: Banneville, A.S]]		[[Category: Banneville, A.S]]
	[[Category: ~~Ferraro~~, ~~G]]~~		[[Category: Cornaciu, I]]
	~~[[Category: Merlino, A~~]]

OCA: Protected "9rtf" [edit=sysop:move=sysop]

2025-07-09T15:15:11Z

Protected "9rtf" [edit=sysop:move=sysop]

← Older revision	Revision as of 15:15, 9 July 2025
(No difference)

OCA: New page: '''Unreleased structure''' The entry 9rtf is ON HOLD until sometime in the future Authors: Paolillo, M., Ferraro, G., Banneville, A.S., Cornaciu, I., Pica, A., Merlino, A. Description:...

2025-07-09T15:15:10Z

New page: '''Unreleased structure''' The entry 9rtf is ON HOLD until sometime in the future Authors: Paolillo, M., Ferraro, G., Banneville, A.S., Cornaciu, I., Pica, A., Merlino, A. Description:...

New page

'''Unreleased structure'''

The entry 9rtf is ON HOLD until sometime in the future

Authors: Paolillo, M., Ferraro, G., Banneville, A.S., Cornaciu, I., Pica, A., Merlino, A.

Description: Crystal structure of the human serum transferrin with Fe(III) bound at the C-lobe only
[[Category: Unreleased Structures]]
[[Category: Paolillo, M]]
[[Category: Cornaciu, I]]
[[Category: Pica, A]]
[[Category: Banneville, A.S]]
[[Category: Ferraro, G]]
[[Category: Merlino, A]]