Adaptin 3D structures - Revision history

Michal Harel at 09:22, 11 September 2024

2024-09-11T09:22:52Z

Michal Harel at 10:10, 22 August 2022

2022-08-22T10:10:07Z

← Older revision		Revision as of 10:10, 22 August 2022
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	**[[2iv9]] – hAP2β2 appendage domain + eps15 peptide<br />		**[[2iv9]] – hAP2β2 appendage domain + eps15 peptide<br />
	**[[2iv8]] – hAP2β2 appendage domain + B-arrestin peptide<br />		**[[2iv8]] – hAP2β2 appendage domain + B-arrestin peptide<br />
	**[[6yai]] – hAP2β2 + clathrin – Cryo EM<br />		**[[6yai]], [[7om8]] – hAP2β2 + clathrin – Cryo EM<br />
			**[[7ohi]], [[7ohz]], [[7oi5]], [[7oiq]] – hAP2β2 + F-BAR<br />
	**[[1mj7]] – hAP2β4 appendage domain <br />		**[[1mj7]] – hAP2β4 appendage domain <br />

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	**[[6bnt]] – hAP2μ2 C-terminal + insulin receptor substrate peptide <br />		**[[6bnt]] – hAP2μ2 C-terminal + insulin receptor substrate peptide <br />
			**[[7ofp]] – rAP2μ1 C-terminal - rat<br />
	**[[4emz]], [[4en2]] – mAP2μ1 C-terminal + NEF + MHC-I<br />		**[[4emz]], [[4en2]] – mAP2μ1 C-terminal + NEF + MHC-I<br />
	**[[3h85]] – rAP2μ1 C-terminal + PTDINSPKIγ peptide - rat<br />		**[[3h85]] – rAP2μ1 C-terminal + PTDINSPKIγ peptide - rat<br />
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	**[[6owo]] – mAP2α2 + APβ + APμ + APσ + NECAP – Cryo EM<br />		**[[6owo]] – mAP2α2 + APβ + APμ + APσ + NECAP – Cryo EM<br />
	**[[6oxl]] – mAP2α2 + APβ + APμ + APσ + NECAP + DNA – Cryo EM<br />		**[[6oxl]] – mAP2α2 + APβ + APμ + APσ + NECAP + DNA – Cryo EM<br />
			**[[7rw8]], [[7rw9]], [[7rwb]] – mAP2α2 + APβ + APμ + APσ – Cryo EM<br />
			**[[7rwc]] – mAP2α2 + APβ + APμ + APσ + SGIP – Cryo EM<br />
			**[[7rwa]] – mAP2α2 + APβ + APμ + APσ + Tgn38 peptide – Cryo EM<br />
			**[[7oho]], [[7z5c]] – rAP2α2 + hAPβ + rAPμ + mAPσ<br />
	**[[6owt]] – rAP2α2 + rAPβ + mAPμ + rAPσ + tetherin – Cryo EM<br />		**[[6owt]] – rAP2α2 + rAPβ + mAPμ + rAPσ + tetherin – Cryo EM<br />

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	**[[4afi]] - hAP3δ1/mVAMP7<br />		**[[4afi]] - hAP3δ1/mVAMP7<br />

			*AP3μ + AP3δ

			**[[7p3x]], [[7p3y]], [[7p3z]] – yAP3 – yeast - Cryo EM<br />

	*AP4β		*AP4β

Michal Harel at 10:07, 7 March 2021

2021-03-07T10:07:26Z

← Older revision		Revision as of 10:07, 7 March 2021
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	**[[2iv9]] – hAP2β2 appendage domain + eps15 peptide<br />		**[[2iv9]] – hAP2β2 appendage domain + eps15 peptide<br />
	**[[2iv8]] – hAP2β2 appendage domain + B-arrestin peptide<br />		**[[2iv8]] – hAP2β2 appendage domain + B-arrestin peptide<br />
			**[[6yai]] – hAP2β2 + clathrin – Cryo EM<br />
	**[[1mj7]] – hAP2β4 appendage domain <br />		**[[1mj7]] – hAP2β4 appendage domain <br />

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	**[[2xa7]] – rAP2α2 + APβ + APμ + APσ + cargo peptide<br />		**[[2xa7]] – rAP2α2 + APβ + APμ + APσ + cargo peptide<br />
	**[[6qh5]] – rAPα + rAPβ + APμ-1 + APσ<br />		**[[6qh5]] – rAPα + rAPβ + APμ-1 + APσ<br />
	**[[~~6owt~~]] – rAPα + ~~rAPβ~~ + ~~APμ~~-1 + ~~APσ~~ + ~~tetherin-~~NEF ~~– Cryo EM~~ <br />		**[[6uri]] – rAPα + hAPβ + hAPμ-1 + hAPσ + NEF <br />
	**[[6qh6]], [[6qh7]] – rAPα + rAPβ + APμ-1 + APσ + TGN38 peptide + CD4 peptide<br />		**[[6qh6]], [[6qh7]] – rAPα + rAPβ + APμ-1 + APσ + TGN38 peptide + CD4 peptide<br />
			**[[6yah]], [[6yae]] – rAP2α2 + hAPβ + rAPμ + mAPσ – Cryo EM<br />
			**[[6yaf]] – rAPα2 + hAPβ + rAPμ + mAPσ + hTGN38 peptide – Cryo EM<br />
			**[[6owo]] – mAP2α2 + APβ + APμ + APσ + NECAP – Cryo EM<br />
			**[[6oxl]] – mAP2α2 + APβ + APμ + APσ + NECAP + DNA – Cryo EM<br />
			**[[6owt]] – rAP2α2 + rAPβ + mAPμ + rAPσ + tetherin – Cryo EM<br />

	*AP2β1 + AP2γ1 + AP2μ1 + AP2σ3		*AP2β1 + AP2γ1 + AP2μ1 + AP2σ3

Michal Harel at 07:41, 31 May 2020

2020-05-31T07:41:33Z

← Older revision		Revision as of 07:41, 31 May 2020
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	**[[6bnt]] – hAP2μ2 C-terminal + insulin receptor substrate peptide <br />		**[[6bnt]] – hAP2μ2 C-terminal + insulin receptor substrate peptide <br />
	**[[~~3h85~~]] – ~~rAP2μ1~~ C-terminal + ~~PTDINSPKIγ peptide~~<br />		**[[4emz]], [[4en2]] – mAP2μ1 C-terminal + NEF + MHC-I<br />
	**[[~~4emz]], [[4en2~~]] – ~~mAP2μ1~~ C-terminal + ~~nef + MHC~~-I<br />		**[[3h85]] – rAP2μ1 C-terminal + PTDINSPKIγ peptide - rat<br />
	**[[2bp5]] – rAP2μ2 + purinoceptor peptide<br />		**[[2bp5]] – rAP2μ2 + purinoceptor peptide<br />
	**[[1bw8]], [[1i31]] – rAP2μ2 C-terminal + EGFR peptide<br />		**[[1bw8]], [[1i31]] – rAP2μ2 C-terminal + EGFR peptide<br />
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	**[[2jkr]], [[2jkt]] – mAP2α2 + AP2β1 + AP2μ1 + AP2σ1 + CD4 peptide<br />		**[[2jkr]], [[2jkt]] – mAP2α2 + AP2β1 + AP2μ1 + AP2σ1 + CD4 peptide<br />
	**[[2xa7]] – rAP2α2 + APβ + APμ + APσ + cargo peptide<br />		**[[2xa7]] – rAP2α2 + APβ + APμ + APσ + cargo peptide<br />
			**[[6qh5]] – rAPα + rAPβ + APμ-1 + APσ<br />
			**[[6owt]] – rAPα + rAPβ + APμ-1 + APσ + tetherin-NEF – Cryo EM <br />
			**[[6qh6]], [[6qh7]] – rAPα + rAPβ + APμ-1 + APσ + TGN38 peptide + CD4 peptide<br />

	*AP2β1 + AP2γ1 + AP2μ1 + AP2σ3		*AP2β1 + AP2γ1 + AP2μ1 + AP2σ3

Michal Harel at 06:18, 29 April 2020

2020-04-29T06:18:48Z

← Older revision		Revision as of 06:18, 29 April 2020
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	**[[1gyu]], [[2a7b]] – mAP2γ1 appendage domain <br />		**[[1gyu]], [[2a7b]] – mAP2γ1 appendage domain <br />
	**[[1gyv]], [[1gyw]], [[3zy7]] – mAP2γ1 appendage domain (mutant)<br />		**[[1gyv]], [[1gyw]], [[3zy7]] – mAP2γ1 appendage domain (mutant)<br />

	*AP2δ

	**[[4afi]] – hAP2δ1/vesicle-associated membrane protein 7<br />

	*AP2μ; Domain - C-terminal 158-433		*AP2μ; Domain - C-terminal 158-433

Michal Harel at 09:13, 28 April 2020

2020-04-28T09:13:09Z

Show changes

Michal Harel at 11:56, 27 April 2020

2020-04-27T11:56:41Z

← Older revision		Revision as of 11:56, 27 April 2020
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	{{#tree:id=OrganizedByTopic\|openlevels=0\|		{{#tree:id=OrganizedByTopic\|openlevels=0\|

	*~~AP-α-2~~		*AP1γ

	**[[1b9k]], [[1qts]] – ~~mAP~~ appendage domain ~~– mouse~~<br />		**[[1iu1]] – hAP1γ-1 appendage domain 662-785 – human<br />
			**[[4bcx]] – hAP1γ-2 appendage domain<br />
			**[[2e9g]] – hAP1γ-2 appendage domain - NMR<br />
			**[[2ymt]], [[3zhf]] – hAP1γ-2 appendage domain + peptide<br />
			**[[2a7b]] – mAP1γ-1 appendage domain – mouse <br />
			**[[1gyw]], [[1gyv]], [[1gyu]] – mAP1γ-1 appendage domain (mutant) <br />
			**[[3zy7]] – mAP1γ-1 appendage domain (mutant) - NMR<br />

			*AP1μ

			**[[4emz]], [[4en2]] – mAP1μ-1 sorting motif recognition domain 158-423 + NEF + MHC-I<br />

			*AP1β + AP1γ + AP1μ + AP1σ

			**[[6cm9]], [[6d84]] – hAPβ-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + NEF + GTP - Cryo EM<br />
			**[[6dff]], [[6cri]] – hAP1β-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + NEF + ARF1 + GTP - Cryo EM<br />
			**[[4p6z]] – mAP1β-1 + hAP1-γ-1 + mAP1μ-1 + hAP1σ-1 + VPU + bone marrow stromal antigen peptide<br />
			**[[4hmy]] – mAP1β-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + ARF1 + GTP <br />
			**[[1w63]] – rAP1β-1 + mAP1γ-1 + mAP1μ-1 + mAP1σ-3 - rat <br />

			*AP2-α-2 +

			**[[1b9k]], [[1qts]] – mAP2 appendage domain <br />
	**[[1qtp]] – mAP appendage domain (mutant)<br />		**[[1qtp]] – mAP appendage domain (mutant)<br />
	**[[1ky6]], [[1kyd]] – ~~mAP~~ appendage domain + epsin peptide<br />		**[[1ky6]], [[1kyd]] – mAP2 appendage domain + epsin peptide<br />
	**[[1ky7]] – mAP appendage domain + amphiphysin peptide<br />		**[[1ky7]] – mAP appendage domain + amphiphysin peptide<br />
	**[[1kyf]], [[1kyu]] – ~~mAP~~ appendage domain + eps15 peptide<br />		**[[1kyf]], [[1kyu]] – mAP2 appendage domain + eps15 peptide<br />
	**[[1w80]], [[2vj0]] – ~~mAP~~ appendage domain + synaptojanin peptide<br />		**[[1w80]], [[2vj0]] – mAP2 appendage domain + synaptojanin peptide<br />
	**[[3hs8]] – ~~mAP~~ appendage domain + intersectin peptide<br />		**[[3hs8]] – mAP2 appendage domain + intersectin peptide<br />

	*AP-β		*AP2-β

	**[[1e42]] – ~~hAP~~-1 appendage domain - human<br />		**[[1e42]] – hAP2-1 appendage domain - human<br />
	**[[2g30]] – ~~hAP~~-1 appendage domain + ARH peptide<br />		**[[2g30]] – hAP2-1 appendage domain + ARH peptide<br />
	**[[3h1z]] – ~~hAP~~-1 appendage domain + PTDINSPKI-γ peptide<br />		**[[3h1z]] – hAP2-1 appendage domain + PTDINSPKI-γ peptide<br />
	**[[3hs9]] – ~~hAP~~-1 appendage domain + intersectin peptide<br />		**[[3hs9]] – hAP2-1 appendage domain + intersectin peptide<br />
	**[[2iv9]] – ~~hAP~~-2 appendage domain + eps15 peptide<br />		**[[2iv9]] – hAP2-2 appendage domain + eps15 peptide<br />
	**[[2iv8]] – ~~hAP~~-2 appendage domain + B-arrestin peptide<br />		**[[2iv8]] – hAP2-2 appendage domain + B-arrestin peptide<br />
	**[[1mj7]] – hAP-4 appendage domain <br />		**[[1mj7]] – hAP-4 appendage domain <br />

Michal Harel at 09:38, 21 March 2019

2019-03-21T09:38:05Z

← Older revision		Revision as of 09:38, 21 March 2019
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	===3D structures of ~~adaptin~~===		===3D structures of [[Adaptin]]===

	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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	**[[4p6z]] – mAP-1 + VPU + bone marrow stromal antigen<br />		**[[4p6z]] – mAP-1 + VPU + bone marrow stromal antigen<br />
	}}		}}
			[[Category: Topic Page]]

Michal Harel: New page: ===3D structures of adaptin=== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *AP-α-2 **1b9k, 1qts – m...

2019-02-28T08:57:52Z

New page: ===3D structures of adaptin=== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *AP-α-2 **1b9k, 1qts – m...

New page

===3D structures of adaptin===

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

*AP-α-2

**[[1b9k]], [[1qts]] – mAP appendage domain – mouse 
**[[1qtp]] – mAP appendage domain (mutant) 
**[[1ky6]], [[1kyd]] – mAP appendage domain + epsin peptide 
**[[1ky7]] – mAP appendage domain + amphiphysin peptide 
**[[1kyf]], [[1kyu]] – mAP appendage domain + eps15 peptide 
**[[1w80]], [[2vj0]] – mAP appendage domain + synaptojanin peptide 
**[[3hs8]] – mAP appendage domain + intersectin peptide 

*AP-β

**[[1e42]] – hAP-1 appendage domain - human 
**[[2g30]] – hAP-1 appendage domain + ARH peptide 
**[[3h1z]] – hAP-1 appendage domain + PTDINSPKI-γ peptide 
**[[3hs9]] – hAP-1 appendage domain + intersectin peptide 
**[[2iv9]] – hAP-2 appendage domain + eps15 peptide 
**[[2iv8]] – hAP-2 appendage domain + B-arrestin peptide 
**[[1mj7]] – hAP-4 appendage domain 

*AP-γ

**[[1iu1]] – hAP-1 ear domain 
**[[1gyu]], [[2a7b]] – mAP-1 appendage domain 
**[[1gyv]], [[1gyw]], [[3zy7]] – mAP-1 appendage domain (mutant) 
**[[2e9g]], [[4bcx]] – hAP-2 ear domain 
**[[2ymt]] – hAP-2 ear domain + peptide 
**[[3zhf]] – hAP-2 ear domain + large envelope protein peptide 

*AP-δ-1

**[[4afi]] – hAP-1/vesicle-associated membrane protein 7 

*AP-μ

**[[3h85]] – rAP-1 appendage domain + PTDINSPKIγ peptide 
**[[4emz]], [[4en2]] – mAP-1 sorting motif recognition domain + nef + MHC-I 
**[[2bp5]] – rAP-2 + purinoceptor peptide 
**[[1bw8]], [[1i31]] – rAP-2 C-terminal + EGFR peptide 
**[[1bxx]] – rAP-2 C-terminal + TGN38 peptide 
**[[1hes]] – rAP-2 C-terminal + selectin peptide 
**[[5c7z]], [[5fpi]] – rAP-2 C terminal + integrin peptide 
**[[2pr9]] – rAP-2 C-terminal + GABA receptor peptide 
**[[5wrm]], [[5wrl]], [[5wrk]] – rAP-2 C-terminal + insulin receptor substrate peptide 
**[[4ikn]] – rAP-3 + TGN38 sorting peptide 
**[[3l81]], [[4mdr]] – hAP-4 + amyloid beta-A4 peptide 
**[[6bnt]] – hAP-2 C-terminal + insulin receptor substrate peptide 

*AP-α2 + AP-σ

**[[4nee]] – rAP-2 + HIV-1 NEF 

*AP-α2 + AP-β + AP-σ

**[[4uqi]] – rAP-2 + VPU 

*AP-α + AP-β + AP-μ + AP-σ

**[[2vgl]] – rAPα-2 + APβ-1 + APμ-1 + APσ-1 
**[[4uqi]] – rAPα-2 + APβ-2 + APμ-2 + APσ-1 
**[[2jkr]], [[2jkt]] – mAPα-2 + APβ-1 + APμ-1 + APσ-1 + CD4 peptide 
**[[2xa7]] – rAPα-2 + APβ + APμ + APσ + cargo peptide 

*AP-β-1 + AP-γ-1 + AP-μ-1 + AP-σ-3

**[[6dff]], [[6d84]], [[6d83]], [[6cri]], [[6cm9]] – hAPβ-1 + APμ-1 + APσ-3 + ARF1 + tetherin-NEF – Cryo EM 

*AP-γ + AP-β + AP-μ + AP-σ

**[[1w63]] – mAP-1 
**[[4hmy]] – mAP-1 + ADP-ribosylation factor 
**[[4p6z]] – mAP-1 + VPU + bone marrow stromal antigen 
}}

← Older revision		Revision as of 09:22, 11 September 2024
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	**[[2vgl]] – rAP2α2 + AP2β1 + AP2μ1 + AP2σ1 <br />		**[[2vgl]] – rAP2α2 + AP2β1 + AP2μ1 + AP2σ1 <br />
	**[[4uqi]] – rAP2α2 + AP2β2 + AP2μ2 + AP2σ1 <br />		**[[4uqi]] – rAP2α2 + AP2β2 + AP2μ2 + AP2σ1 <br />
	**[[2jkr]], [[2jkt]] – mAP2α2 + AP2β1 + AP2μ1 + AP2σ1 + CD4 peptide<br />
	**[[2xa7]] – rAP2α2 + APβ + APμ + APσ + cargo peptide<br />		**[[2xa7]] – rAP2α2 + APβ + APμ + APσ + cargo peptide<br />
	**[[6qh5]] – rAPα + rAPβ + APμ-1 + APσ<br />		**[[6qh5]] – rAPα + rAPβ + APμ-1 + APσ<br />
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	**[[6yah]], [[6yae]] – rAP2α2 + hAPβ + rAPμ + mAPσ – Cryo EM<br />		**[[6yah]], [[6yae]] – rAP2α2 + hAPβ + rAPμ + mAPσ – Cryo EM<br />
	**[[6yaf]] – rAPα2 + hAPβ + rAPμ + mAPσ + hTGN38 peptide – Cryo EM<br />		**[[6yaf]] – rAPα2 + hAPβ + rAPμ + mAPσ + hTGN38 peptide – Cryo EM<br />
			**[[2jkr]], [[2jkt]] – mAP2α2 + AP2β1 + AP2μ1 + AP2σ1 + CD4 peptide<br />
	**[[6owo]] – mAP2α2 + APβ + APμ + APσ + NECAP – Cryo EM<br />		**[[6owo]] – mAP2α2 + APβ + APμ + APσ + NECAP – Cryo EM<br />
	**[[6oxl]] – mAP2α2 + APβ + APμ + APσ + NECAP + DNA – Cryo EM<br />		**[[6oxl]] – mAP2α2 + APβ + APμ + APσ + NECAP + DNA – Cryo EM<br />
	**[[7rw8]], [[7rw9]], [[7rwb]] – mAP2α2 + APβ + APμ + APσ – Cryo EM<br />		**[[7rw8]], [[7rw9]], [[7rwb]] – mAP2α2 + APβ + APμ + APσ – Cryo EM<br />
	**[[7rwc]] – mAP2α2 + APβ + APμ + APσ + SGIP – Cryo EM<br />		**[[7rwc]] – mAP2α2 + APβ + APμ + APσ + SGIP – Cryo EM<br />
	**[[7rwa]] – mAP2α2 + APβ + APμ + APσ + Tgn38 peptide – Cryo EM<br />		**[[7rwa]], [[8t1o]] – mAP2α2 + APβ + APμ + APσ + Tgn38 peptide – Cryo EM<br />
	**[[7oho]], [[7z5c]] – rAP2α2 + hAPβ + rAPμ + mAPσ<br />		**[[7oho]], [[7z5c]] – rAP2α2 + hAPβ + rAPμ + mAPσ<br />
	**[[6owt]] – rAP2α2 + rAPβ + mAPμ + rAPσ + tetherin – Cryo EM<br />		**[[6owt]] – rAP2α2 + rAPβ + mAPμ + rAPσ + tetherin – Cryo EM<br />
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	**[[6dff]], [[6d84]], [[6d83]], [[6cri]], [[6cm9]] – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + tetherin-NEF – Cryo EM <br />		**[[6dff]], [[6d84]], [[6d83]], [[6cri]], [[6cm9]] – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + tetherin-NEF – Cryo EM <br />
			**[[7ux3]], [[8d4c]], [[8d4d]], [[8d4e]], [[8d4f]], [[8d4g]], [[8d9r]], [[8d9s]], [[8d9t]], [[8d9u]], [[8d9w]] – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + NEF + MHC-I – Cryo EM <br />
			**[[7r4h]] – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + HSTING – Cryo EM <br />


	*AP2γ1 + AP2β1 + AP2μ1 + AP2σ1		*AP2γ1 + AP2β1 + AP2μ1 + AP2σ1