Colony-stimulating factor - Revision history

Alexander Berchansky at 14:01, 11 May 2021

2021-05-11T14:01:55Z

← Older revision		Revision as of 14:01, 11 May 2021
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	== Structural highlights ==		== Structural highlights ==

	The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are <scene name='80/801266/Cv/5'>two binding sites between the molecules designated site I and site II</scene><ref>PMID:26235028</ref>. <scene name='80/801266/Cv/4'>All interactions</scene>.		The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are <scene name='80/801266/Cv/5'>two binding sites between the molecules designated site I and site II</scene><ref>PMID:26235028</ref>. <scene name='80/801266/Cv/4'>All interactions</scene>. See also [[Colony-stimulating factor receptor]]

	==3D structures of colony-stimulating factor==		==3D structures of colony-stimulating factor==

Michal Harel at 09:56, 14 May 2019

2019-05-14T09:56:59Z

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 </StructureSection>
 == References ==
 <references/>
 [[Category:Topic Page]]

Michal Harel at 09:55, 14 May 2019

2019-05-14T09:55:47Z

← Older revision		Revision as of 09:55, 14 May 2019
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	The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are <scene name='80/801266/Cv/5'>two binding sites between the molecules designated site I and site II</scene><ref>PMID:26235028</ref>. <scene name='80/801266/Cv/4'>All interactions</scene>.		The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are <scene name='80/801266/Cv/5'>two binding sites between the molecules designated site I and site II</scene><ref>PMID:26235028</ref>. <scene name='80/801266/Cv/4'>All interactions</scene>.

			==3D structures of colony-stimulating factor==
			[[Colony-stimulating factor 3D structures]]

	</StructureSection>		</StructureSection>

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	**[[2gmf]], [[3uf2]] - hM-CSF - human<br />		**[[2gmf]], [[3uf2]] - hM-CSF - human<br />
	**[[5lxf]] - hM-CSF (mutant)<br />		**[[5lxf]] - hM-CSF (mutant)<br />
	**[[4adq]], [[4adf]] - hM-CSF + BARF1<br />		**[[4adq]], [[4adf]], [[4fa8]] - hM-CSF + BARF1<br />
	**[[3uez]] - hM-CSF (mutant) + BARF1<br />		**[[3uez]] - hM-CSF (mutant) + BARF1<br />
	**[[4wrm]], [[4wrl]] - hM-CSF + CSF receptor<br />		**[[4wrm]], [[4wrl]] - hM-CSF + CSF receptor<br />
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	*Granulocyte colony stimulating factor		*Granulocyte colony stimulating factor

	**[[1bgc]] - G-CSF - bovine<br />
	**[[1bgd]], [[1bge]] - G-CSF - dog<br />
	**[[1rhg]] - hG-CSF <br />		**[[1rhg]] - hG-CSF <br />
	**[[1gnc]] - hG-CSF - NMR<br />		**[[1gnc]] - hG-CSF - NMR<br />
	**[[5gw9]] - hG-CSF (mutant)<br />		**[[5gw9]], [[5zo6]] - hG-CSF (mutant)<br />
	**[[2d9q]], [[1pgr]], [[1cd9]] - hG-CSF + CSF receptor<br />		**[[2d9q]], [[1pgr]], [[1cd9]] - hG-CSF + CSF receptor<br />
			**[[1bgc]] - G-CSF - bovine<br />
			**[[1bgd]], [[1bge]] - G-CSF - dog<br />
	**[[1gcf]], [[1cto]] - mG-CSF C-terminal of LBD - NMR<br />		**[[1gcf]], [[1cto]] - mG-CSF C-terminal of LBD - NMR<br />
	}}		}}

Alexander Berchansky at 12:26, 19 November 2018

2018-11-19T12:26:17Z

← Older revision		Revision as of 12:26, 19 November 2018
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	== Structural highlights ==		== Structural highlights ==

	The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are two binding sites between the molecules designated site I and site II<ref>PMID:26235028</ref>.		The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are <scene name='80/801266/Cv/5'>two binding sites between the molecules designated site I and site II</scene><ref>PMID:26235028</ref>. <scene name='80/801266/Cv/4'>All interactions</scene>.
	</StructureSection>		</StructureSection>

Alexander Berchansky at 12:13, 19 November 2018

2018-11-19T12:13:28Z

← Older revision		Revision as of 12:13, 19 November 2018
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	== Structural highlights ==		== Structural highlights ==

	The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/2'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are two binding sites between the molecules designated site I and site II<ref>PMID:26235028</ref>.		The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/3'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are two binding sites between the molecules designated site I and site II<ref>PMID:26235028</ref>.
	</StructureSection>		</StructureSection>

Alexander Berchansky at 12:02, 19 November 2018

2018-11-19T12:02:07Z

← Older revision		Revision as of 12:02, 19 November 2018
Line 15:		Line 15:
	== Structural highlights ==		== Structural highlights ==

	The structure of the complex between M-CSF and its receptor shows that a dimer of M-CSF binds to 2 molecules of the receptor. There are two binding sites between the molecules designated site I and site II<ref>PMID:26235028</ref>.		The structure of the complex between M-CSF and its receptor shows that a <scene name='80/801266/Cv/2'>dimer of M-CSF binds to 2 molecules of the receptor</scene>. There are two binding sites between the molecules designated site I and site II<ref>PMID:26235028</ref>.
	</StructureSection>		</StructureSection>

Alexander Berchansky at 11:51, 19 November 2018

2018-11-19T11:51:57Z

← Older revision		Revision as of 11:51, 19 November 2018
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	<StructureSection load='4wrl' size='340' side='right' caption='Glycosylated human macrophage colony-stimulating factor (~~pink~~ and ~~yellow~~) complex with macrophage colony-stimulating factor 1 receptor (~~grey~~ and green) (PDB code [[4wrl]])' scene=''>		<StructureSection load='4wrl' size='340' side='right' caption='Glycosylated human macrophage colony-stimulating factor (deeppink and salmon) complex with macrophage colony-stimulating factor 1 receptor (deepskyblue and green) (PDB code [[4wrl]])' scene='80/801266/Cv/1'>

	== Function ==		== Function ==

Michal Harel at 09:08, 15 November 2018

2018-11-15T09:08:37Z

← Older revision		Revision as of 09:08, 15 November 2018
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	**[[4adq]], [[4adf]] - hM-CSF + BARF1<br />		**[[4adq]], [[4adf]] - hM-CSF + BARF1<br />
	**[[3uez]] - hM-CSF (mutant) + BARF1<br />		**[[3uez]] - hM-CSF (mutant) + BARF1<br />
	**[[4wrm]], [[4wrl]] - hG-CSF + CSF receptor<br />		**[[4wrm]], [[4wrl]] - hM-CSF + CSF receptor<br />
	**[[3uf5]] - mM-CSF - mouse<br />		**[[3uf5]] - mM-CSF - mouse<br />
	**[[3ejj]] - mM-CSF + CSF receptor<br />		**[[3ejj]] - mM-CSF + CSF receptor<br />

Michal Harel at 08:28, 14 November 2018

2018-11-14T08:28:53Z

← Older revision		Revision as of 08:28, 14 November 2018
Line 15:		Line 15:
	== Structural highlights ==		== Structural highlights ==

			The structure of the complex between M-CSF and its receptor shows that a dimer of M-CSF binds to 2 molecules of the receptor. There are two binding sites between the molecules designated site I and site II<ref>PMID:26235028</ref>.
	</StructureSection>		</StructureSection>

Michal Harel at 07:48, 14 November 2018

2018-11-14T07:48:17Z

← Older revision		Revision as of 07:48, 14 November 2018
Line 1:		Line 1:
	<StructureSection load='4wrl' size='340' side='right' caption='Glycosylated human macrophage colony-stimulating factor (~~green~~ and yellow) complex with macrophage colony-stimulating factor 1 receptor (grey and ~~pink~~) (PDB code [[4wrl]])' scene=''>		<StructureSection load='4wrl' size='340' side='right' caption='Glycosylated human macrophage colony-stimulating factor (pink and yellow) complex with macrophage colony-stimulating factor 1 receptor (grey and green) (PDB code [[4wrl]])' scene=''>

	== Function ==		== Function ==