Complement factor 3D structures - Revision history

Michal Harel at 11:24, 3 February 2025

2025-02-03T11:24:04Z

← Older revision		Revision as of 11:24, 3 February 2025
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	**[[6rur]] – hCFB + complement C3 α+β chains<br />		**[[6rur]] – hCFB + complement C3 α+β chains<br />
	**[[2xwj]] – hCFB (mutant) + complement C3 α+β chains<br />		**[[2xwj]] – hCFB (mutant) + complement C3 α+β chains<br />
	**[[~~2xwb~~]] – hCFB ~~(mutant)~~ + ~~hCFD (mutant)~~ + complement ~~C3 α~~+β chains<br />		**[[8enu]] – hCFB + complement C3B a+b chains + lufaxin – Cryo EM<br />
			**[[8uin]] – hCFB + complement C3B a+b chains + albicin – Cryo EM<br />
			**[[8eok]] – hCFB + complement C3B a+b chains + lufaxin + factor Xa – Cryo EM<br />
	**[[3hrz]], [[3hs0]] – hCFB (mutant) + cobra venom factor<br />		**[[3hrz]], [[3hs0]] – hCFB (mutant) + cobra venom factor<br />
	**[[7jtn]], [[7jtq]] – hCFB + DNA<br />		**[[7jtn]], [[7jtq]] – hCFB + DNA<br />
			**[[6qsw]], [[6qsx]], [[6rav]], [[6t8v]], [[6t8w]], [[6tbu]] – hCFB protease domain + inhibitor<br />

	*Complement factor D		*Complement factor D
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	**[[5o35]] – hCFH + complement C3 α chain <br />		**[[5o35]] – hCFH + complement C3 α chain <br />
	**[[7wki]] – hCFH + nanobody <br />		**[[7wki]] – hCFH + nanobody <br />
			**[[9f7i]] – hCFH + CRASP-2<br />
			**[[7zjm]] – hCFH + CSPZ<br />
			**[[6zh1]] – hCFH + CFH-binding protein<br />
	**[[6xz6]] – CFH + factor H receptor - bovine <br />		**[[6xz6]] – CFH + factor H receptor - bovine <br />

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	**[[6rur]] – hCFP + complement C3 + CFB + protein inhibitor<br />		**[[6rur]] – hCFP + complement C3 + CFB + protein inhibitor<br />
	**[[6ruv]] – hCFP + complement C3 + CFB + nanobody + protein inhibitor<br />		**[[6ruv]] – hCFP + complement C3 + CFB + nanobody + protein inhibitor<br />
			**[[7noz]] – hCFP + complement C3 + CFB + nanobody + properdin <br />

	}}		}}

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Michal Harel at 09:15, 29 November 2022

2022-11-29T09:15:57Z

← Older revision		Revision as of 09:15, 29 November 2022
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	**[[2g7i]] – hCFH 19-20 sushi domains <br />		**[[2g7i]] – hCFH 19-20 sushi domains <br />
	**[[3kxv]], [[3r62]] – hCFH 19-20 sushi domains (mutant) <br />		**[[3kxv]], [[3r62]] – hCFH 19-20 sushi domains (mutant) <br />
	**[[6xz6]] – CFH + factor H receptor - bovine <br />

	*Complement factor H complexes		*Complement factor H complexes
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	**[[5o32]] – hCFH + hCFI + complement C3 α+β chains <br />		**[[5o32]] – hCFH + hCFI + complement C3 α+β chains <br />
	**[[5o35]] – hCFH + complement C3 α chain <br />		**[[5o35]] – hCFH + complement C3 α chain <br />
			**[[7wki]] – hCFH + nanobody <br />
			**[[6xz6]] – CFH + factor H receptor - bovine <br />

	*Complement factor I		*Complement factor I

Michal Harel at 09:14, 29 November 2022

2022-11-29T09:14:46Z

← Older revision		Revision as of 09:14, 29 November 2022
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	*Complement factor D complexes		*Complement factor D complexes

	**[[1bio]], [[1dfp]], [[1dic]], [[5fbe]], [[5fbi]], [[5fck]], [[5fcr]], [[5mt0]], [[5mt4]], [[5nar]], [[5nat]], [[5naw]], [[5nb6]], [[5nb7]], [[5nba]], [[5tca]], [[5tcc]],[[6qmr]], [[6qmt]], [[6fut]], [[6fuj]], [[6fui]], [[6fuh]], [[6fug]], [[6ftz]], [[6fty]] – hCFD + inhibitor <br />		**[[1bio]], [[1dfp]], [[1dic]], [[5fbe]], [[5fbi]], [[5fck]], [[5fcr]], [[5mt0]], [[5mt4]], [[5nar]], [[5nat]], [[5naw]], [[5nb6]], [[5nb7]], [[5nba]], [[5tca]], [[5tcc]],[[6qmr]], [[6qmt]], [[6fut]], [[6fuj]], [[6fui]], [[6fuh]], [[6fug]], [[6ftz]], [[6fty]], [[8d95]], [[8dea]], [[8dg6]] – hCFD + inhibitor <br />
	**[[4d9r]], [[6vmj]], [[6vmk]] – hCFD + antibody<br />		**[[4d9r]], [[6vmj]], [[6vmk]] – hCFD + antibody<br />

Michal Harel at 08:02, 9 June 2021

2021-06-09T08:02:00Z

← Older revision		Revision as of 08:02, 9 June 2021
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	**[[2xwb]] – hCFB (mutant) + hCFD (mutant) + complement C3 α+β chains<br />		**[[2xwb]] – hCFB (mutant) + hCFD (mutant) + complement C3 α+β chains<br />
	**[[3hrz]], [[3hs0]] – hCFB (mutant) + cobra venom factor<br />		**[[3hrz]], [[3hs0]] – hCFB (mutant) + cobra venom factor<br />
			**[[7jtn]], [[7jtq]] – hCFB + DNA<br />

	*Complement factor D		*Complement factor D
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	**[[1bio]], [[1dfp]], [[1dic]], [[5fbe]], [[5fbi]], [[5fck]], [[5fcr]], [[5mt0]], [[5mt4]], [[5nar]], [[5nat]], [[5naw]], [[5nb6]], [[5nb7]], [[5nba]], [[5tca]], [[5tcc]],[[6qmr]], [[6qmt]], [[6fut]], [[6fuj]], [[6fui]], [[6fuh]], [[6fug]], [[6ftz]], [[6fty]] – hCFD + inhibitor <br />		**[[1bio]], [[1dfp]], [[1dic]], [[5fbe]], [[5fbi]], [[5fck]], [[5fcr]], [[5mt0]], [[5mt4]], [[5nar]], [[5nat]], [[5naw]], [[5nb6]], [[5nb7]], [[5nba]], [[5tca]], [[5tcc]],[[6qmr]], [[6qmt]], [[6fut]], [[6fuj]], [[6fui]], [[6fuh]], [[6fug]], [[6ftz]], [[6fty]] – hCFD + inhibitor <br />
	**[[4d9r]] – hCFD + antibody<br />		**[[4d9r]], [[6vmj]], [[6vmk]] – hCFD + antibody<br />

	*Complement factor H		*Complement factor H
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	**[[6rus]], [[6rv6]], [[6s08]], [[6s0a]], [[6sej]] – hCFP <br />		**[[6rus]], [[6rv6]], [[6s08]], [[6s0a]], [[6sej]] – hCFP <br />
	**[[6s0b]] – hCFP + complement C3 <br />		**[[6s0b]] – hCFP + complement C3 <br />
			**[[6rur]] – hCFP + complement C3 + CFB + protein inhibitor<br />
	**[[6ruv]] – hCFP + complement C3 + CFB + nanobody + protein inhibitor<br />		**[[6ruv]] – hCFP + complement C3 + CFB + nanobody + protein inhibitor<br />

Michal Harel at 07:45, 7 July 2020

2020-07-07T07:45:22Z

← Older revision		Revision as of 07:45, 7 July 2020
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	**[[2g7i]] – hCFH 19-20 sushi domains <br />		**[[2g7i]] – hCFH 19-20 sushi domains <br />
	**[[3kxv]], [[3r62]] – hCFH 19-20 sushi domains (mutant) <br />		**[[3kxv]], [[3r62]] – hCFH 19-20 sushi domains (mutant) <br />
			**[[6xz6]] – CFH + factor H receptor - bovine <br />

	*Complement factor H complexes		*Complement factor H complexes
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	**[[2xrc]] – hCFI <br />		**[[2xrc]] – hCFI <br />

			*Complement factor P or properdin

			**[[6rus]], [[6rv6]], [[6s08]], [[6s0a]], [[6sej]] – hCFP <br />
			**[[6s0b]] – hCFP + complement C3 <br />
			**[[6ruv]] – hCFP + complement C3 + CFB + nanobody + protein inhibitor<br />

	}}		}}

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Joel L. Sussman at 19:09, 21 August 2019

2019-08-21T19:09:46Z

← Older revision		Revision as of 19:09, 21 August 2019
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	**[[1rs0]] – hCFB BB fragment (mutant) + DIP<br />		**[[1rs0]] – hCFB BB fragment (mutant) + DIP<br />
	**[[1rtk]] – hCFB BB fragment (mutant) + guanidinobenzoate<br />		**[[1rtk]] – hCFB BB fragment (mutant) + guanidinobenzoate<br />
	**[[~~5m6w~~]] – hCFB + complement C3 α+β chains<br />		**[[6rur]] – hCFB + complement C3 α+β chains<br />
	**[[2xwj]] – hCFB (mutant) + complement C3 α+β chains<br />		**[[2xwj]] – hCFB (mutant) + complement C3 α+β chains<br />
	**[[2xwb]] – hCFB (mutant) + hCFD (mutant) + complement C3 α+β chains<br />		**[[2xwb]] – hCFB (mutant) + hCFD (mutant) + complement C3 α+β chains<br />

Michal Harel at 08:10, 15 May 2019

2019-05-15T08:10:40Z

← Older revision		Revision as of 08:10, 15 May 2019
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	*Complement factor B		*Complement factor B

	**[[2ok5]] – hCFB residues 26-764<br />		**[[2ok5]] – hCFB residues 26-764 - human<br />
	**[[1dle]] – hCFB serine protease domain residues 470-764<br />		**[[1dle]] – hCFB serine protease domain residues 470-764<br />
	**[[1q0p]] – hCFB residues 254-476 (mutant) <br />		**[[1q0p]] – hCFB residues 254-476 (mutant) <br />
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	*Complement factor H		*Complement factor H

	**[[1haq]], [[3gau]], [[3gav]], [[3gaw]] – hCFH ~~– human~~ - NMR<br />		**[[1haq]], [[3gau]], [[3gav]], [[3gaw]] – hCFH - NMR<br />
	**[[2rlp]] – hCFH 1-2 sushi domains - NMR <br />		**[[2rlp]] – hCFH 1-2 sushi domains - NMR <br />
	**[[2rlq]] – hCFH 2-3 sushi domains - NMR <br />		**[[2rlq]] – hCFH 2-3 sushi domains - NMR <br />

Michal Harel: New page: ==3D structures of complement factor== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Complement factor B **[[2o...

2019-05-15T08:07:43Z

New page: ==3D structures of complement factor== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Complement factor B **[[2o...

New page

==3D structures of complement factor==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

*Complement factor B

**[[2ok5]] – hCFB residues 26-764 
**[[1dle]] – hCFB serine protease domain residues 470-764 
**[[1q0p]] – hCFB residues 254-476 (mutant) 
**[[1rrk]] – hCFB BB fragment residues 243-764 (mutant) 

*Complement factor B complexes

**[[1rs0]] – hCFB BB fragment (mutant) + DIP 
**[[1rtk]] – hCFB BB fragment (mutant) + guanidinobenzoate 
**[[5m6w]] – hCFB + complement C3 α+β chains 
**[[2xwj]] – hCFB (mutant) + complement C3 α+β chains 
**[[2xwb]] – hCFB (mutant) + hCFD (mutant) + complement C3 α+β chains 
**[[3hrz]], [[3hs0]] – hCFB (mutant) + cobra venom factor 

*Complement factor D

**[[1dsu]], [[1hfd]] – hCFD 
**[[1dst]], [[2xw9]], [[2xwa]], [[4cbn]], [[4cbo]] – hCFD (mutant) 
**[[1fdp]] – hCFD proenzyme 

*Complement factor D complexes

**[[1bio]], [[1dfp]], [[1dic]], [[5fbe]], [[5fbi]], [[5fck]], [[5fcr]], [[5mt0]], [[5mt4]], [[5nar]], [[5nat]], [[5naw]], [[5nb6]], [[5nb7]], [[5nba]], [[5tca]], [[5tcc]],[[6qmr]], [[6qmt]], [[6fut]], [[6fuj]], [[6fui]], [[6fuh]], [[6fug]], [[6ftz]], [[6fty]] – hCFD + inhibitor 
**[[4d9r]] – hCFD + antibody 

*Complement factor H

**[[1haq]], [[3gau]], [[3gav]], [[3gaw]] – hCFH – human - NMR 
**[[2rlp]] – hCFH 1-2 sushi domains - NMR 
**[[2rlq]] – hCFH 2-3 sushi domains - NMR 
**[[2qfg]] – hCFH 1-5 sushi domains 
**[[2yby]] – mCFH 6-8 sushi domains (mutant) - mouse 
**[[2ic4]] – hCFH 6-8 sushi domains (mutant) 
**[[2jgw]] – hCFH 7 sushi domain – NMR 
**[[2jgx]] – hCFH 7 sushi domain (mutant) 
**[[4b2r]] – hCFH 10-11 sushi domains - NMR 
**[[4b2s]] – hCFH 11-12 sushi domains - NMR 
**[[2kms]] – hCFH 12-13 sushi domains – NMR 
**[[1hfi]] – hCFH 15 sushi domain – NMR 
**[[1hfh]] – hCFH 15-16 sushi domains – NMR 
**[[2qfh]] – hCFH 16-20 sushi domains - NMR 
**[[3sw0]] – hCFH 18-20 sushi domains 
**[[2bzm]] – hCFH 19-20 sushi domains – NMR 
**[[3kzj]] – hCFH 19-20 sushi domains (mutant) – NMR 
**[[2g7i]] – hCFH 19-20 sushi domains 
**[[3kxv]], [[3r62]] – hCFH 19-20 sushi domains (mutant) 

*Complement factor H complexes

**[[2wii]] – hCFH 1-4 sushi domains + complement C3 
**[[2w80]], [[2w81]], [[4ayd]], [[4aye]], [[4ayi]], [[4aym]] – hCFH 6-7 sushi domains + factor H binding protein 
**[[2uwn]], [[2v8e]] – hCFH 6-8 sushi domains + sucrose octasulfate 
**[[4k12]] – hCFH 9 sushi domain + choline binding protein A 
**[[3oxu]], [[4ont]], [[4zh1]] – hCFH 19-20 sushi domains + complement C3 
**[[2xqw]] – hCFH 19-20 sushi domains (mutant) + complement C3 
**[[4j38]] – hCFH 19-20 sushi domains (mutant) + outer surface protein E 
**[[4k12]] – hCFH 9 sushi domain + choline binding protein A 
**[[5nbq]] – hCFH + complement C3 α chain + outer surface protein 
**[[5o32]] – hCFH + hCFI + complement C3 α+β chains 
**[[5o35]] – hCFH + complement C3 α chain 

*Complement factor I

**[[2xrc]] – hCFI 

}}

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