Constans - Revision history

Jaime Prilusky at 10:26, 23 June 2026

2026-06-23T10:26:41Z

← Older revision		Revision as of 10:26, 23 June 2026
Line 17:		Line 17:

	[[3D structures of constans]]		[[3D structures of constans]]
			</StructureSection>
	== References ==		== References ==
	<references/>		<references/>

Michal Harel at 08:00, 23 June 2026

2026-06-23T08:00:14Z

← Older revision		Revision as of 08:00, 23 June 2026
Line 1:		Line 1:

			<StructureSection load='7vsq' size='340' side='right' caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code [[7vsq]])' scene=''>
			__TOC__
	==Structural highlights: CONSTANS ==		==Structural highlights: CONSTANS ==
	~~<StructureSection load='7vsq' size='340' side='right' caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]])' scene=''>~~
	~~__TOC__~~
	'''Constans''' (CO) is is a Zinc finger containing a domain known as B-boxes. Cysteine and histidine coordinate zinc. Mutations identified within the residues resulted in late flowering which is disadvantageous to reproduction patterns, and suggests they are highly conserved. B-boxes are involved in protein-protein interactions. The C-terminal contains 40 main amino acids (C-terminal contains 70-80 in entirety). In arabidopsis, 32 B-box transcription proteins have been identified thus far. CO, which is considered a BBX1, activates the expression of FT by binding to the CORE1 and CORE2 of the FT promoter. Each B-box transcription protein serves to regulate flowering by stimulating or repressing FT hormone. BBX28 is known to decrease FT transcription, specifically in the late afternoons and dark periods. BBX28 is able to interact with CO through the N-terminus. This works by decreasing recruitment of CO to the FT locus. Constans-like genes (COLs) are very genetically related homologs to Constans (CO). Specifically, CO1 has a greater than 80% amino acid genetic similarity to CO. While identity is similar, function of CO1 varies among identified organisms.		'''Constans''' (CO) is is a Zinc finger containing a domain known as B-boxes. Cysteine and histidine coordinate zinc. Mutations identified within the residues resulted in late flowering which is disadvantageous to reproduction patterns, and suggests they are highly conserved. B-boxes are involved in protein-protein interactions. The C-terminal contains 40 main amino acids (C-terminal contains 70-80 in entirety). In arabidopsis, 32 B-box transcription proteins have been identified thus far. CO, which is considered a BBX1, activates the expression of FT by binding to the CORE1 and CORE2 of the FT promoter. Each B-box transcription protein serves to regulate flowering by stimulating or repressing FT hormone. BBX28 is known to decrease FT transcription, specifically in the late afternoons and dark periods. BBX28 is able to interact with CO through the N-terminus. This works by decreasing recruitment of CO to the FT locus. Constans-like genes (COLs) are very genetically related homologs to Constans (CO). Specifically, CO1 has a greater than 80% amino acid genetic similarity to CO. While identity is similar, function of CO1 varies among identified organisms.

Michal Harel at 07:57, 23 June 2026

2026-06-23T07:57:57Z

← Older revision		Revision as of 07:57, 23 June 2026
Line 1:		Line 1:
	==Structural highlights: CONSTANS ==		==Structural highlights: CONSTANS ==
	<StructureSection load='7vsq' size='340' side='right' caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]])~~, [[Resolution\|resolution]] 1.68Å~~' scene=''>		<StructureSection load='7vsq' size='340' side='right' caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]])' scene=''>
	__TOC__		__TOC__
	'''Constans''' (CO) is is a Zinc finger containing a domain known as B-boxes. Cysteine and histidine coordinate zinc. Mutations identified within the residues resulted in late flowering which is disadvantageous to reproduction patterns, and suggests they are highly conserved. B-boxes are involved in protein-protein interactions. The C-terminal contains 40 main amino acids (C-terminal contains 70-80 in entirety). In arabidopsis, 32 B-box transcription proteins have been identified thus far. CO, which is considered a BBX1, activates the expression of FT by binding to the CORE1 and CORE2 of the FT promoter. Each B-box transcription protein serves to regulate flowering by stimulating or repressing FT hormone. BBX28 is known to decrease FT transcription, specifically in the late afternoons and dark periods. BBX28 is able to interact with CO through the N-terminus. This works by decreasing recruitment of CO to the FT locus. Constans-like genes (COLs) are very genetically related homologs to Constans (CO). Specifically, CO1 has a greater than 80% amino acid genetic similarity to CO. While identity is similar, function of CO1 varies among identified organisms.		'''Constans''' (CO) is is a Zinc finger containing a domain known as B-boxes. Cysteine and histidine coordinate zinc. Mutations identified within the residues resulted in late flowering which is disadvantageous to reproduction patterns, and suggests they are highly conserved. B-boxes are involved in protein-protein interactions. The C-terminal contains 40 main amino acids (C-terminal contains 70-80 in entirety). In arabidopsis, 32 B-box transcription proteins have been identified thus far. CO, which is considered a BBX1, activates the expression of FT by binding to the CORE1 and CORE2 of the FT promoter. Each B-box transcription protein serves to regulate flowering by stimulating or repressing FT hormone. BBX28 is known to decrease FT transcription, specifically in the late afternoons and dark periods. BBX28 is able to interact with CO through the N-terminus. This works by decreasing recruitment of CO to the FT locus. Constans-like genes (COLs) are very genetically related homologs to Constans (CO). Specifically, CO1 has a greater than 80% amino acid genetic similarity to CO. While identity is similar, function of CO1 varies among identified organisms.

Michal Harel at 07:57, 23 June 2026

2026-06-23T07:57:18Z

← Older revision		Revision as of 07:57, 23 June 2026
Line 1:		Line 1:
	==Structural highlights: CONSTANS ==		==Structural highlights: CONSTANS ==
	<StructureSection load='7vsq ' size='340' side='right' caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]]), [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='7vsq' size='340' side='right' caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]]), [[Resolution\|resolution]] 1.68Å' scene=''>
	__TOC__		__TOC__
	'''Constans''' (CO) is is a Zinc finger containing a domain known as B-boxes. Cysteine and histidine coordinate zinc. Mutations identified within the residues resulted in late flowering which is disadvantageous to reproduction patterns, and suggests they are highly conserved. B-boxes are involved in protein-protein interactions. The C-terminal contains 40 main amino acids (C-terminal contains 70-80 in entirety). In arabidopsis, 32 B-box transcription proteins have been identified thus far. CO, which is considered a BBX1, activates the expression of FT by binding to the CORE1 and CORE2 of the FT promoter. Each B-box transcription protein serves to regulate flowering by stimulating or repressing FT hormone. BBX28 is known to decrease FT transcription, specifically in the late afternoons and dark periods. BBX28 is able to interact with CO through the N-terminus. This works by decreasing recruitment of CO to the FT locus. Constans-like genes (COLs) are very genetically related homologs to Constans (CO). Specifically, CO1 has a greater than 80% amino acid genetic similarity to CO. While identity is similar, function of CO1 varies among identified organisms.		'''Constans''' (CO) is is a Zinc finger containing a domain known as B-boxes. Cysteine and histidine coordinate zinc. Mutations identified within the residues resulted in late flowering which is disadvantageous to reproduction patterns, and suggests they are highly conserved. B-boxes are involved in protein-protein interactions. The C-terminal contains 40 main amino acids (C-terminal contains 70-80 in entirety). In arabidopsis, 32 B-box transcription proteins have been identified thus far. CO, which is considered a BBX1, activates the expression of FT by binding to the CORE1 and CORE2 of the FT promoter. Each B-box transcription protein serves to regulate flowering by stimulating or repressing FT hormone. BBX28 is known to decrease FT transcription, specifically in the late afternoons and dark periods. BBX28 is able to interact with CO through the N-terminus. This works by decreasing recruitment of CO to the FT locus. Constans-like genes (COLs) are very genetically related homologs to Constans (CO). Specifically, CO1 has a greater than 80% amino acid genetic similarity to CO. While identity is similar, function of CO1 varies among identified organisms.

Jaime Prilusky at 12:29, 6 February 2025

2025-02-06T12:29:38Z

← Older revision		Revision as of 12:29, 6 February 2025
Line 1:		Line 1:
	==Structural highlights: CONSTANS ==		==Structural highlights: CONSTANS ==
	<StructureSection load='7vsq ' size='340' side='right'caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]]', [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='7vsq ' size='340' side='right' caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]]), [[Resolution\|resolution]] 1.68Å' scene=''>
	__TOC__		__TOC__
	'''Constans''' (CO) is is a Zinc finger containing a domain known as B-boxes. Cysteine and histidine coordinate zinc. Mutations identified within the residues resulted in late flowering which is disadvantageous to reproduction patterns, and suggests they are highly conserved. B-boxes are involved in protein-protein interactions. The C-terminal contains 40 main amino acids (C-terminal contains 70-80 in entirety). In arabidopsis, 32 B-box transcription proteins have been identified thus far. CO, which is considered a BBX1, activates the expression of FT by binding to the CORE1 and CORE2 of the FT promoter. Each B-box transcription protein serves to regulate flowering by stimulating or repressing FT hormone. BBX28 is known to decrease FT transcription, specifically in the late afternoons and dark periods. BBX28 is able to interact with CO through the N-terminus. This works by decreasing recruitment of CO to the FT locus. Constans-like genes (COLs) are very genetically related homologs to Constans (CO). Specifically, CO1 has a greater than 80% amino acid genetic similarity to CO. While identity is similar, function of CO1 varies among identified organisms.		'''Constans''' (CO) is is a Zinc finger containing a domain known as B-boxes. Cysteine and histidine coordinate zinc. Mutations identified within the residues resulted in late flowering which is disadvantageous to reproduction patterns, and suggests they are highly conserved. B-boxes are involved in protein-protein interactions. The C-terminal contains 40 main amino acids (C-terminal contains 70-80 in entirety). In arabidopsis, 32 B-box transcription proteins have been identified thus far. CO, which is considered a BBX1, activates the expression of FT by binding to the CORE1 and CORE2 of the FT promoter. Each B-box transcription protein serves to regulate flowering by stimulating or repressing FT hormone. BBX28 is known to decrease FT transcription, specifically in the late afternoons and dark periods. BBX28 is able to interact with CO through the N-terminus. This works by decreasing recruitment of CO to the FT locus. Constans-like genes (COLs) are very genetically related homologs to Constans (CO). Specifically, CO1 has a greater than 80% amino acid genetic similarity to CO. While identity is similar, function of CO1 varies among identified organisms.

Michal Harel at 08:28, 9 January 2023

2023-01-09T08:28:02Z

← Older revision		Revision as of 08:28, 9 January 2023
Line 15:		Line 15:
	==CONSTANS 3D structures==		==CONSTANS 3D structures==

	[[3D structures of ~~constants~~]]		[[3D structures of constans]]

	== References ==		== References ==

Michal Harel at 08:27, 9 January 2023

2023-01-09T08:27:35Z

@@ Line 15: / Line 15: @@
 ==CONSTANS 3D structures==
-[[3D structures of constans]]
+[[3D structures of constants]]
 == References ==

Michal Harel at 08:25, 9 January 2023

2023-01-09T08:25:10Z

← Older revision		Revision as of 08:25, 9 January 2023
Line 14:		Line 14:

	==CONSTANS 3D structures==		==CONSTANS 3D structures==

			[[3D structures of constans]]

	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
	{{#tree:id=OrganizedByTopic\|openlevels=0\|		{{#tree:id=OrganizedByTopic\|openlevels=0\|

	* ~~CONSTANS~~		* Constans

	**[[7wsj]], [[7vsq]] – AtCON B-box domain 2-110 - ''Arabidopsis thaliana''<br />		**[[7wsj]], [[7vsq]] – AtCON B-box domain 2-110 - ''Arabidopsis thaliana''<br />
	**[[7cvo]], [[7cvq]] – AtCON 290-357 + nuclear transcription factor + DNA<br />		**[[7cvo]], [[7cvq]] – AtCON 290-357 + nuclear transcription factor + DNA<br />

	* ~~CONSTANS~~-like		* Constans-like

	**[[7vsp]] – AtCOL-2 B-box domain 1-120 <br />		**[[7vsp]] – AtCOL-2 B-box domain 1-120 <br />

Jaime Prilusky: Constans CO moved to Constans: requested by Editor

2023-01-08T14:09:02Z

Constans CO moved to Constans: requested by Editor

← Older revision	Revision as of 14:09, 8 January 2023
(No difference)

Michal Harel at 11:15, 8 January 2023

2023-01-08T11:15:25Z

← Older revision		Revision as of 11:15, 8 January 2023
Line 1:		Line 1:
	==Structural highlights: CONSTANS CO==		==Structural highlights: CONSTANS ==
	<StructureSection load='7vsq ' size='340' side='right'caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]]', [[Resolution\|resolution]] 1.68Å' scene=''>		<StructureSection load='7vsq ' size='340' side='right'caption='CONSTANS B-Box domains complex with Zn++ ions (PDB code[[7vsq]]', [[Resolution\|resolution]] 1.68Å' scene=''>
	__TOC__		__TOC__
Line 29:		Line 29:
	}}		}}

	~~</StructureSection>~~
	== References ==		== References ==
	<references/>		<references/>