Factor IX 3D structures - Revision history

Michal Harel at 09:26, 5 June 2025

2025-06-05T09:26:57Z

← Older revision		Revision as of 09:26, 5 June 2025
Line 14:		Line 14:
	*Factor IX protein complexes		*Factor IX protein complexes

	**[[7ahu]], [[7ahv]] - hIXa light+heavy chain + antibody<br />		**[[7ahu]], [[7ahv]], [[8ol9]] - hIXa light+heavy chain + antibody<br />
	**[[3kcg]] - hIXa light+heavy chains + antithrombin-III+ pentasaccharide<br />		**[[3kcg]] - hIXa light+heavy chains + antithrombin-III+ pentasaccharide<br />
	**[[1nl0]] – hIX GLA domain + anti-factor IX antibody<br />		**[[1nl0]] – hIX GLA domain + anti-factor IX antibody<br />

Michal Harel at 07:54, 22 July 2021

2021-07-22T07:54:29Z

← Older revision		Revision as of 07:54, 22 July 2021
Line 10:		Line 10:
	**[[1ixa]] - hIX EGF-like domain - NMR<br />		**[[1ixa]] - hIX EGF-like domain - NMR<br />
	**[[6mv4]] - hIXa light+heavy chain<br />		**[[6mv4]] - hIXa light+heavy chain<br />
			**[[1pfx]] – pIXa 8-147,183-409 - pig<br />

	*Factor IX complexes		*Factor IX protein complexes

	**[[~~3lc3~~]], [[~~3lc5]] – hIXa light+heavy chain + benzothiophene inhibitor<br />~~		**[[7ahu]], [[7ahv]] - hIXa light+heavy chain + antibody<br />
	**[[6x5j]], [[6x5l]] - hIXa light+heavy chain + pyrimidine derivative inhibitor<br />
	**[[6x5p]] - hIXa light+heavy chain ~~(mutant) + pyrimidine derivative inhibitor<br />~~
	**[[5vgy]] - hIXa EGF-like domain + ~~trisaccharide~~<br />
	**[[3kcg]] - hIXa light+heavy chains + antithrombin-III+ pentasaccharide<br />		**[[3kcg]] - hIXa light+heavy chains + antithrombin-III+ pentasaccharide<br />
	**[[2wph]], [[2wpi]], [[2wpj]], [[2wpk]], [[2wpl]] - hIXa light+heavy chains (mutant) + FPR-chloromethyl ketone<br />
	**[[2wpm]] - hIXa light+heavy chains (mutant) + EGR-chloromethyl ketone<br />
	**[[1nl0]] – hIX GLA domain + anti-factor IX antibody<br />		**[[1nl0]] – hIX GLA domain + anti-factor IX antibody<br />
	**[[1rfn]] - hIXa light+heavy chains EGF2-catalytic domain + inhibitor<br />
	**[[4yzu]], [[4z0k]], [[5tno]] – hIX peptidase S1 and EGF-like 2 domains + inhibitor <br />
	**[[4zae]], [[5egm]], [[5jb8]], [[5jb9]], [[5jba]], [[5jbb]], [[5jbc]], [[5tnt]] – hIX peptidase S1 and EGF-like 2 domains (mutant) + inhibitor <br />
	**[[4wm0]] – hIX EGF-like domain + xyloside gxylosyltransferase + glucopyranose derivative<br />		**[[4wm0]] – hIX EGF-like domain + xyloside gxylosyltransferase + glucopyranose derivative<br />
	**[[4wma]] – hIX EGF-like domain + xyloside gxylosyltransferase + UDP-glucose <br />		**[[4wma]] – hIX EGF-like domain + xyloside gxylosyltransferase + UDP-glucose <br />
Line 33:		Line 26:
	**[[5f85]] – hIX EGFlike domain + glucosyltransferase + UDP <br />		**[[5f85]] – hIX EGFlike domain + glucosyltransferase + UDP <br />
	**[[6rfk]] – hIX light+heavy chains + peptide - NMR <br />		**[[6rfk]] – hIX light+heavy chains + peptide - NMR <br />
	**[[1x7a]] - pIXa light+heavy chains + inhibitor – pig<br />
	**[[1pfx]] – pIXa +FPR<br />
	**[[1j34]], [[1j35]] - bIX GLA domain + IX-binding protein – bovine<br />		**[[1j34]], [[1j35]] - bIX GLA domain + IX-binding protein – bovine<br />
	**[[~~1pfx~~]] – pIXa +~~FPR~~<br />
			*Factor IX small molecule complexes

			**[[3lc3]], [[3lc5]] – hIXa light+heavy chain + benzothiophene inhibitor<br />
			**[[6x5j]], [[6x5l]] - hIXa light+heavy chain + pyrimidine derivative inhibitor<br />
			**[[6x5p]] - hIXa light+heavy chain (mutant) + pyrimidine derivative inhibitor<br />
			**[[5vgy]] - hIXa EGF-like domain + trisaccharide<br />
			**[[2wph]], [[2wpi]], [[2wpj]], [[2wpk]], [[2wpl]] - hIXa light+heavy chains (mutant) + FPR-chloromethyl ketone<br />
			**[[2wpm]] - hIXa light+heavy chains (mutant) + EGR-chloromethyl ketone<br />
			**[[1rfn]] - hIXa light+heavy chains EGF2-catalytic domain + inhibitor<br />
			**[[4yzu]], [[4z0k]], [[5tno]] – hIX peptidase S1 and EGF-like 2 domains + inhibitor <br />
			**[[4zae]], [[5egm]], [[5jb8]], [[5jb9]], [[5jba]], [[5jbb]], [[5jbc]], [[5tnt]] – hIX peptidase S1 and EGF-like 2 domains (mutant) + inhibitor <br />
			**[[1x7a]] - pIXa light+heavy chains + inhibitor <br />
	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 10:12, 10 February 2021

2021-02-10T10:12:07Z

← Older revision		Revision as of 10:12, 10 February 2021
Line 9:		Line 9:
	**[[1edm]], [[5vyg]] – hIX EGF-like domain<br />		**[[1edm]], [[5vyg]] – hIX EGF-like domain<br />
	**[[1ixa]] - hIX EGF-like domain - NMR<br />		**[[1ixa]] - hIX EGF-like domain - NMR<br />
	**[[6mv4]] - ~~hIX~~ light+heavy chain<br />		**[[6mv4]] - hIXa light+heavy chain<br />

	*Factor IX complexes		*Factor IX complexes

Michal Harel at 09:21, 26 July 2020

2020-07-26T09:21:18Z

← Older revision		Revision as of 09:21, 26 July 2020
Line 14:		Line 14:

	**[[3lc3]], [[3lc5]] – hIXa light+heavy chain + benzothiophene inhibitor<br />		**[[3lc3]], [[3lc5]] – hIXa light+heavy chain + benzothiophene inhibitor<br />
			**[[6x5j]], [[6x5l]] - hIXa light+heavy chain + pyrimidine derivative inhibitor<br />
			**[[6x5p]] - hIXa light+heavy chain (mutant) + pyrimidine derivative inhibitor<br />
	**[[5vgy]] - hIXa EGF-like domain + trisaccharide<br />		**[[5vgy]] - hIXa EGF-like domain + trisaccharide<br />
	**[[3kcg]] - hIXa light+heavy chains + antithrombin-III+ pentasaccharide<br />		**[[3kcg]] - hIXa light+heavy chains + antithrombin-III+ pentasaccharide<br />

Michal Harel: New page: ==3D structures of factor IX== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Factor IX; Domains – GLA 1-47; EG...

2019-06-26T06:48:52Z

New page: ==3D structures of factor IX== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Factor IX; Domains – GLA 1-47; EG...

New page

==3D structures of factor IX==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

*Factor IX; Domains – GLA 1-47; EGF-like 92-130; heavy 227-461; light 133-185

**[[1mgx]], [[1cfi]], [[1cfh]] - hIX GLA domain – human – NMR 
**[[1edm]], [[5vyg]] – hIX EGF-like domain 
**[[1ixa]] - hIX EGF-like domain - NMR 
**[[6mv4]] - hIX light+heavy chain 

*Factor IX complexes

**[[3lc3]], [[3lc5]] – hIXa light+heavy chain + benzothiophene inhibitor 
**[[5vgy]] - hIXa EGF-like domain + trisaccharide 
**[[3kcg]] - hIXa light+heavy chains + antithrombin-III+ pentasaccharide 
**[[2wph]], [[2wpi]], [[2wpj]], [[2wpk]], [[2wpl]] - hIXa light+heavy chains (mutant) + FPR-chloromethyl ketone 
**[[2wpm]] - hIXa light+heavy chains (mutant) + EGR-chloromethyl ketone 
**[[1nl0]] – hIX GLA domain + anti-factor IX antibody 
**[[1rfn]] - hIXa light+heavy chains EGF2-catalytic domain + inhibitor 
**[[4yzu]], [[4z0k]], [[5tno]] – hIX peptidase S1 and EGF-like 2 domains + inhibitor 
**[[4zae]], [[5egm]], [[5jb8]], [[5jb9]], [[5jba]], [[5jbb]], [[5jbc]], [[5tnt]] – hIX peptidase S1 and EGF-like 2 domains (mutant) + inhibitor 
**[[4wm0]] – hIX EGF-like domain + xyloside gxylosyltransferase + glucopyranose derivative 
**[[4wma]] – hIX EGF-like domain + xyloside gxylosyltransferase + UDP-glucose 
**[[4wnh]] – hIX EGF-like domain + xyloside gxylosyltransferase + UDP-xylose 
**[[4wmb]] – hIX EGF-like domain + xyloside gxylosyltransferase + UDP 
**[[4wmi]], [[4wmk]], [[4wn2]] – hIX EGF-like domain + xyloside gxylosyltransferase + glucopyranose derivative + UDP 
**[[5f86]] – hIX EGF-like domain + glucosyltransferase 
**[[5f84]] – hIX EGF-like domain + glucosyltransferase + UDP-glucose 
**[[5f85]] – hIX EGFlike domain + glucosyltransferase + UDP 
**[[6rfk]] – hIX light+heavy chains + peptide - NMR 
**[[1x7a]] - pIXa light+heavy chains + inhibitor – pig 
**[[1pfx]] – pIXa +FPR 
**[[1j34]], [[1j35]] - bIX GLA domain + IX-binding protein – bovine 
**[[1pfx]] – pIXa +FPR 
}}

[[Category:Topic Page]]