https://proteopedia.org/index.php?action=history&feed=atom&title=P53_3D_structures P53 3D structures - Revision history 2026-10-03T17:20:08Z Revision history for this page on the wiki MediaWiki 1.43.8 https://proteopedia.org/index.php?title=P53_3D_structures&diff=4441508&oldid=prev Jaime Prilusky at 17:14, 22 April 2026 2026-04-22T17:14:02Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:14, 22 April 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5">Line 5:</td> <td colspan="2" class="diff-lineno">Line 5:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2ocj]], [[2xwr]], [[2ybg<del style="font-weight: bold; text-decoration: none;">]], [[8f2i</del>]] – h-p53 DBD – human&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2ocj]], [[2xwr]], [[2ybg]] – h-p53 DBD – human&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1uol]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2pcx]], [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]], [[7eax]], [[7eeu]], [[7v97]], [[8cg7]], [[8e7a]], [[8e7b]], [[8qwk]], [[8qwl]], [[8qwm]], [[8qwn]], [[8qwo]], [[8qwp]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1uol]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2pcx]], [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]], [[7eax]], [[7eeu]], [[7v97]], [[8cg7]], [[8e7a]], [[8e7b]], [[8qwk]], [[8qwl]], [[8qwm]], [[8qwn]], [[8qwo]], [[8qwp]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td></tr> </table> Jaime Prilusky https://proteopedia.org/index.php?title=P53_3D_structures&diff=4437438&oldid=prev Michal Harel at 07:45, 15 April 2026 2026-04-15T07:45:36Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:45, 15 April 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>(Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}) <del style="font-weight: bold; text-decoration: none;">==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>(Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}})  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{#tree:id=OrganizedByTopic|openlevels=0|</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{#tree:id=OrganizedByTopic|openlevels=0|</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> </table> Michal Harel https://proteopedia.org/index.php?title=P53_3D_structures&diff=4437437&oldid=prev Michal Harel at 07:45, 15 April 2026 2026-04-15T07:45:04Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:45, 15 April 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">(Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}) ==</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{#tree:id=OrganizedByTopic|openlevels=0|</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> </table> Michal Harel https://proteopedia.org/index.php?title=P53_3D_structures&diff=4437436&oldid=prev Michal Harel at 07:40, 15 April 2026 2026-04-15T07:40:33Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:40, 15 April 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l17">Line 17:</td> <td colspan="2" class="diff-lineno">Line 17:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain complex with small molecule</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain complex with small molecule</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2x0u]], [[2x0v]], [[2x0w]], [[4agl]], [[4agm]], [[4agn]], [[4ago]], [[4agp]], [[4agq]], [[<del style="font-weight: bold; text-decoration: none;">5aolj</del>], [[5aol]] – h-p53 DBD (mutant) + benzene derivative&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2x0u]], [[2x0v]], [[2x0w]], [[4agl]], [[4agm]], [[4agn]], [[4ago]], [[4agp]], [[4agq]], [[<ins style="font-weight: bold; text-decoration: none;">5aoj]</ins>], [[5aol]] – h-p53 DBD (mutant) + benzene derivative&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3zme]], [[8a92]], [[8rbc]], [[9g5h]], [[9g5u]], [[9g6t]] - h-p53 DBD (mutant) + pyrazol derivative&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3zme]], [[8a92]], [[8rbc]], [[9g5h]], [[9g5u]], [[9g6t]] - h-p53 DBD (mutant) + pyrazol derivative&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[8rba]], [[8rbb]] - h-p53 DBD (mutant) + pyridine derivative&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[8rba]], [[8rbb]] - h-p53 DBD (mutant) + pyridine derivative&lt;br /&gt;</div></td></tr> </table> Michal Harel https://proteopedia.org/index.php?title=P53_3D_structures&diff=4437435&oldid=prev Michal Harel at 07:39, 15 April 2026 2026-04-15T07:39:17Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:39, 15 April 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">==3D structures of p53 </del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"> </ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> </table> Michal Harel https://proteopedia.org/index.php?title=P53_3D_structures&diff=4437434&oldid=prev Michal Harel at 07:36, 15 April 2026 2026-04-15T07:36:29Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:36, 15 April 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l2">Line 2:</td> <td colspan="2" class="diff-lineno">Line 2:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2ocj]], [[2xwr]], [[2ybg]], [8f2i]] – h-p53 DBD – human&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2ocj]], [[2xwr]], [[2ybg]], <ins style="font-weight: bold; text-decoration: none;">[</ins>[8f2i]] – h-p53 DBD – human&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1uol]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2pcx]], [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]], [[7eax]], [[7eeu]], [[7v97]], [[8cg7]], [[8e7a]], [[8e7b]], [[8qwk]], [[8qwl]], [[8qwm]], [[8qwn]], [[8qwo]], [[8qwp]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1uol]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2pcx]], [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]], [[7eax]], [[7eeu]], [[7v97]], [[8cg7]], [[8e7a]], [[8e7b]], [[8qwk]], [[8qwl]], [[8qwm]], [[8qwn]], [[8qwo]], [[8qwp]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td></tr> </table> Michal Harel https://proteopedia.org/index.php?title=P53_3D_structures&diff=4437433&oldid=prev Michal Harel at 07:35, 15 April 2026 2026-04-15T07:35:50Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:35, 15 April 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>==3D structures of p53 <del style="font-weight: bold; text-decoration: none;">(Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}) ==</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>==3D structures of p53  </div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">{{#tree:id=OrganizedByTopic|openlevels=0|</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[<del style="font-weight: bold; text-decoration: none;">2xwr</del>]], [[<del style="font-weight: bold; text-decoration: none;">2ocj</del>]], [[2ybg]], [8f2i]] – h-p53 DBD – human&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[<ins style="font-weight: bold; text-decoration: none;">2ocj</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2xwr</ins>]], [[2ybg]], [8f2i]] – h-p53 DBD – human&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[<del style="font-weight: bold; text-decoration: none;">2wgx</del>]], [[<del style="font-weight: bold; text-decoration: none;">3d05</del>]], [[<del style="font-weight: bold; text-decoration: none;">3d06</del>]], [[<del style="font-weight: bold; text-decoration: none;">3d07</del>]], [[<del style="font-weight: bold; text-decoration: none;">3d08</del>]], [[<del style="font-weight: bold; text-decoration: none;">3d09]], [[2pcx</del>]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[<del style="font-weight: bold; text-decoration: none;">2bim</del>]], [[<del style="font-weight: bold; text-decoration: none;">2bin</del>]], [[<del style="font-weight: bold; text-decoration: none;">2bio</del>]], [[<del style="font-weight: bold; text-decoration: none;">2bip</del>]], [[<del style="font-weight: bold; text-decoration: none;">2biq</del>]], [[<del style="font-weight: bold; text-decoration: none;">1uol</del>]], [[<del style="font-weight: bold; text-decoration: none;">4kvp</del>]], [[<del style="font-weight: bold; text-decoration: none;">4lo9</del>]], [[<del style="font-weight: bold; text-decoration: none;">4loe</del>]], [[<del style="font-weight: bold; text-decoration: none;">4lof</del>]], [[<del style="font-weight: bold; text-decoration: none;">4ibq</del>]], [[<del style="font-weight: bold; text-decoration: none;">4ibs</del>]], [[<del style="font-weight: bold; text-decoration: none;">4ibt</del>]], [[<del style="font-weight: bold; text-decoration: none;">4iby</del>]], [[<del style="font-weight: bold; text-decoration: none;">4ibz</del>]], [[<del style="font-weight: bold; text-decoration: none;">4ijt</del>]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]], [[7eax]], [[7eeu]], [[7v97]], [[8e7a]], [[8e7b]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[<ins style="font-weight: bold; text-decoration: none;">1uol</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2bim</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2bin</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2bio</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2bip</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2biq</ins>]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[<ins style="font-weight: bold; text-decoration: none;">2pcx]], [[2wgx</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3d05</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3d06</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3d07</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3d08</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3d09</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4ibq</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4ibs</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4ibt</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4iby</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4ibz</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4ijt</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4kvp</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4lo9</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4loe</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4lof</ins>]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]], [[7eax]], [[7eeu]], [[7v97<ins style="font-weight: bold; text-decoration: none;">]], [[8cg7</ins>]], [[8e7a]], [[8e7b<ins style="font-weight: bold; text-decoration: none;">]], [[8qwk]], [[8qwl]], [[8qwm]], [[8qwn]], [[8qwo]], [[8qwp</ins>]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[<del style="font-weight: bold; text-decoration: none;">2ioi</del>]], [[<del style="font-weight: bold; text-decoration: none;">2ioo</del>]], [[<del style="font-weight: bold; text-decoration: none;">1hu8</del>]] – m-p53 DBD – mouse&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[<ins style="font-weight: bold; text-decoration: none;">1hu8</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2ioi</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2ioo</ins>]] – m-p53 DBD – mouse&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1t4w]] – p53-like DBD – &#039;&#039;Caenoharbditis elegans&#039;&#039;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1t4w]] – p53-like DBD – &#039;&#039;Caenoharbditis elegans&#039;&#039;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain complex with DNA</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain complex with DNA</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[<del style="font-weight: bold; text-decoration: none;">3igk</del>]], [[<del style="font-weight: bold; text-decoration: none;">3igl</del>]], [[<del style="font-weight: bold; text-decoration: none;">3kz8</del>]], [[<del style="font-weight: bold; text-decoration: none;">3kmd</del>]], [[<del style="font-weight: bold; text-decoration: none;">2ac0</del>]], [[<del style="font-weight: bold; text-decoration: none;">2ady</del>]], [[<del style="font-weight: bold; text-decoration: none;">2ahi</del>]], [[<del style="font-weight: bold; text-decoration: none;">2ata</del>]], [[<del style="font-weight: bold; text-decoration: none;">1tsr</del>]], [[<del style="font-weight: bold; text-decoration: none;">1tup</del>]], [[4hje]], [[5bua]], [[<del style="font-weight: bold; text-decoration: none;">6fj5</del>]], [[<del style="font-weight: bold; text-decoration: none;">5mg7</del>]], [[<del style="font-weight: bold; text-decoration: none;">5mf7</del>]], [[<del style="font-weight: bold; text-decoration: none;">5mcw</del>]], [[<del style="font-weight: bold; text-decoration: none;">5mcu</del>]], [[<del style="font-weight: bold; text-decoration: none;">5mct</del>]], [[<del style="font-weight: bold; text-decoration: none;">5lgy</del>]] – h-p53 DBD + DNA&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[<ins style="font-weight: bold; text-decoration: none;">1tsr</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">1tup</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2ac0</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2ady</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2ahi</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2ata</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3igk</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3igl</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3kmd</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3kz8</ins>]], [[4hje]], [[5bua]], [[<ins style="font-weight: bold; text-decoration: none;">5mct</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5mcu</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5mcw</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5lgy</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5mf7</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5mg7</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">6fj5</ins>]] – h-p53 DBD + DNA&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[3d0a]], [[3ts8]], [[4ibu]], [[4ibv]], [[4ibw]], [[7b47]], [[7b48]], [[7b49]], [[7b4a]], [[7b4b]], [[7b4c]], [[7b4d]], [[7b4e]], [[7b4f]], [[7b4h]], [[7b4n]], [[7eds]] - h-p53 DBD (mutant) + DNA&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[3d0a]], [[3ts8]], [[4ibu]], [[4ibv]], [[4ibw<ins style="font-weight: bold; text-decoration: none;">]], [[7b46</ins>]], [[7b47]], [[7b48]], [[7b49]], [[7b4a]], [[7b4b]], [[7b4c]], [[7b4d]], [[7b4e]], [[7b4f]], [[7b4h]], [[7b4n]], [[7eds]] - h-p53 DBD (mutant) + DNA&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3q05]], [[3q06]] - h-p53 DBD + TD + DNA&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3q05]], [[3q06]] - h-p53 DBD + TD + DNA&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[<del style="font-weight: bold; text-decoration: none;">3exj</del>]], [[<del style="font-weight: bold; text-decoration: none;">3exl</del>]], [[<del style="font-weight: bold; text-decoration: none;">2p52</del>]], [[<del style="font-weight: bold; text-decoration: none;">2geq</del>]] – m-p53 DBD + DNA</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[<ins style="font-weight: bold; text-decoration: none;">2geq</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2p52</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3exj</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3exl</ins>]] – m-p53 DBD + DNA</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain complex with small molecule</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain complex with small molecule</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2x0u]], [[2x0v]], [[2x0w]], [[4agl]], [[4agm]], [[4agn]], [[4ago]], [[4agp]], [[4agq]], [[<del style="font-weight: bold; text-decoration: none;">5aol]</del>], [[<del style="font-weight: bold; text-decoration: none;">5aoj</del>]] – h-p53 DBD (mutant) + benzene derivative&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2x0u]], [[2x0v]], [[2x0w]], [[4agl]], [[4agm]], [[4agn]], [[4ago]], [[4agp]], [[4agq]], [[<ins style="font-weight: bold; text-decoration: none;">5aolj</ins>], [[<ins style="font-weight: bold; text-decoration: none;">5aol</ins>]] – h-p53 DBD (mutant) + benzene derivative&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[3zme]], [[8a92]] - h-p53 DBD (mutant) + pyrazol derivative&lt;br /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[3zme]], [[8a92<ins style="font-weight: bold; text-decoration: none;">]], [[8rbc]], [[9g5h]], [[9g5u]], [[9g6t</ins>]] - h-p53 DBD (mutant) + pyrazol <ins style="font-weight: bold; text-decoration: none;">derivative&lt;br /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8rba]], [[8rbb]] - h-p53 DBD (mutant) + pyridine </ins>derivative&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[8dc4]] - h-p53 DBD (mutant) + carbazole&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[8dc4]] - h-p53 DBD (mutant) + carbazole&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>**[[<del style="font-weight: bold; text-decoration: none;">5aoi</del>]], [[<del style="font-weight: bold; text-decoration: none;">5ab9</del>]], [[8dc6]], [[8dc7]], [[8dc8]] - h-p53 DBD (mutant) + indole derivative&lt;br /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[<ins style="font-weight: bold; text-decoration: none;">5ab9</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5aoi</ins>]], [[8dc6]], [[8dc7]], [[8dc8]] - h-p53 DBD (mutant) + indole derivative&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2vuk]] - h-p53 DBD + drug&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2vuk]] - h-p53 DBD + drug&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>**[[<del style="font-weight: bold; text-decoration: none;">5g4o</del>]], [[<del style="font-weight: bold; text-decoration: none;">5g4n</del>]], [[<del style="font-weight: bold; text-decoration: none;">5g4m</del>]], [[5aom]], [[<del style="font-weight: bold; text-decoration: none;">5aok</del>]], [[<del style="font-weight: bold; text-decoration: none;">5aba</del>]], [[<del style="font-weight: bold; text-decoration: none;">5a7b</del>]], [[<del style="font-weight: bold; text-decoration: none;">5o1i</del>]], [[<del style="font-weight: bold; text-decoration: none;">5o1h</del>]], [[<del style="font-weight: bold; text-decoration: none;">5o1g</del>]], [[<del style="font-weight: bold; text-decoration: none;">5o1f</del>]], [[5o1e]], [[<del style="font-weight: bold; text-decoration: none;">5o1a</del>]], [[<del style="font-weight: bold; text-decoration: none;">5o1b</del>]], [[<del style="font-weight: bold; text-decoration: none;">5o1c</del>]], [[<del style="font-weight: bold; text-decoration: none;">5o1d</del>]] - h-p53 DBD (mutant) + drug&lt;br /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[<ins style="font-weight: bold; text-decoration: none;">5a7b</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5aba</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5aok</ins>]], [[5aom]], [[<ins style="font-weight: bold; text-decoration: none;">5g4m</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5g4n</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5g4o</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5o1a</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5o1b</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5o1c</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5o1d</ins>]], [[5o1e]], [[<ins style="font-weight: bold; text-decoration: none;">5o1f</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5o1g</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5o1h</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">5o1i</ins>]] - h-p53 DBD (mutant) + drug&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>**[[6gff]], [[<del style="font-weight: bold; text-decoration: none;">6gge</del>]], [[<del style="font-weight: bold; text-decoration: none;">6ggd</del>]], [[6ggc]], [[<del style="font-weight: bold; text-decoration: none;">6ggb</del>]], [[<del style="font-weight: bold; text-decoration: none;">6gga</del>]], [[6si3]], [[6si4]], [[8a31]], [[8a32]] - h-p53 DBD (mutant) + stabilizer&lt;br /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[6gff]], [[<ins style="font-weight: bold; text-decoration: none;">6gga</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">6ggb</ins>]], [[6ggc]], [[<ins style="font-weight: bold; text-decoration: none;">6ggd</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">6gge</ins>]], [[6si3]], [[6si4]], [[8a31]], [[8a32]] - h-p53 DBD (mutant) + stabilizer&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2iom]] - m-p53 DBD + propanol</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2iom]] - m-p53 DBD + propanol</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l39">Line 39:</td> <td colspan="2" class="diff-lineno">Line 39:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[8hll]], [[8hlm]], [[8hln]] - h-p53 DBD + Bcl-2&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[8hll]], [[8hlm]], [[8hln]] - h-p53 DBD + Bcl-2&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[7ygi]] - h-p53 DBD + azurin&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[7ygi]] - h-p53 DBD + azurin&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8fzb]], [[8rci]] - h-p53 DBD + darpin&lt;br /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8j8n]] - h-p53 DBD + zinc finger protein – Cryo EM&lt;br /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 transactivation domain (residues 15-29)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 transactivation domain (residues 15-29)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l47">Line 47:</td> <td colspan="2" class="diff-lineno">Line 48:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2gs0]] – h-p53 TAD + RNA polymerase II transcription factor&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2gs0]] – h-p53 TAD + RNA polymerase II transcription factor&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[7nmi]] - h-p53 TAD + S110P/ANXA2&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[7nmi]] - h-p53 TAD + S110P/ANXA2&lt;br /&gt;</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 tetramerization domain (residues 326-356)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 tetramerization domain (residues 326-356)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[<del style="font-weight: bold; text-decoration: none;">2j0z</del>]], [[<del style="font-weight: bold; text-decoration: none;">3sak</del>]], [[<del style="font-weight: bold; text-decoration: none;">1sae</del>]], [[<del style="font-weight: bold; text-decoration: none;">1saf</del>]], [[<del style="font-weight: bold; text-decoration: none;">1sak</del>]], [[<del style="font-weight: bold; text-decoration: none;">1sal</del>]], [[<del style="font-weight: bold; text-decoration: none;">1olh</del>]], [[<del style="font-weight: bold; text-decoration: none;">1pes</del>]], [[<del style="font-weight: bold; text-decoration: none;">1pet</del>]], [[<del style="font-weight: bold; text-decoration: none;">1olg]], [[1hs5</del>]]– h-p53 TD – NMR&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[<ins style="font-weight: bold; text-decoration: none;">1hs5</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">1olg</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">1pes</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">1pet</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">1sae</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">1saf</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">1sak</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">1sal</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2j0z</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">3sak</ins>]] – h-p53 TD – NMR&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[1c26]], [[<del style="font-weight: bold; text-decoration: none;">1aie</del>]] - h-p53 TD&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** <ins style="font-weight: bold; text-decoration: none;">[[1aie]], </ins>[[1c26]], [[<ins style="font-weight: bold; text-decoration: none;">8uqr</ins>]] - h-p53 TD&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[<del style="font-weight: bold; text-decoration: none;">2j10</del>]], [[<del style="font-weight: bold; text-decoration: none;">2j11</del>]], [[<del style="font-weight: bold; text-decoration: none;">1a1u</del>]] - h-p53 TD (mutant) – NMR&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[<ins style="font-weight: bold; text-decoration: none;">1a1u</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2j10</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">2j11</ins>]] - h-p53 TD (mutant) – NMR&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[7bwn]] - h-p53 TD + GFP&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[7bwn]] - h-p53 TD + GFP&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8uqs]] - p53 TD - opossum&lt;BR /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8uqt]] - p53 TD - shrew&lt;BR /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 tetramerization+DBD domains</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 tetramerization+DBD domains</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[<del style="font-weight: bold; text-decoration: none;">4mzr</del>]], [[<del style="font-weight: bold; text-decoration: none;">3q01</del>]] – h-p53 + DNA&lt;br /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[<ins style="font-weight: bold; text-decoration: none;">3q01</ins>]], [[<ins style="font-weight: bold; text-decoration: none;">4mzr</ins>]] – h-p53 + DNA&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[5xzc]] – h-p53 + P300 – Cryo EM&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[5xzc]] – h-p53 + P300 – Cryo EM&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*p53 full (residues 1-393)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*p53 full (residues 1-393)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8wd2]], [[8xcb]], [[8xce]] – h-p53 &lt;br /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[9s9r]] – h-p53 (mutant) &lt;br /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[6xre]] – h-p53 + RNA polymerase II – Cryo EM&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[6xre]] – h-p53 + RNA polymerase II – Cryo EM&lt;br /&gt;</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8r1f]], [[8r1g]] , [[8zzn]]– h-p53 + ubiquitin protein ligase E3A + E6 – Cryo EM&lt;br /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[9br3]], [[9br4]] – h-p53 + drug&lt;br /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[9s9l]], [[9s9m]], [[9s9n]], [[9s9o]], [[9s9p]], [[9s9q]] – h-p53 (mutant) + drug&lt;br /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Topic Page]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Topic Page]]</div></td></tr> </table> Michal Harel https://proteopedia.org/index.php?title=P53_3D_structures&diff=4278435&oldid=prev Jaime Prilusky at 11:46, 21 November 2024 2024-11-21T11:46:46Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:46, 21 November 2024</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l3">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2xwr]], [[2ocj]], [[2ybg<del style="font-weight: bold; text-decoration: none;">]], [[8f2h</del>]], [8f2i]] – h-p53 DBD – human&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2xwr]], [[2ocj]], [[2ybg]], [8f2i]] – h-p53 DBD – human&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[2pcx]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[1uol]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]], [[7eax]], [[7eeu]], [[7v97]], [[8e7a]], [[8e7b]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[2pcx]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[1uol]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]], [[7eax]], [[7eeu]], [[7v97]], [[8e7a]], [[8e7b]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td></tr> </table> Jaime Prilusky https://proteopedia.org/index.php?title=P53_3D_structures&diff=3835184&oldid=prev Michal Harel at 07:31, 21 August 2023 2023-08-21T07:31:44Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:31, 21 August 2023</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l3">Line 3:</td> <td colspan="2" class="diff-lineno">Line 3:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 DNA-binding domain (residues 94-292)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2xwr]], [[2ocj]], [[2ybg]] – h-p53 DBD – human&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2xwr]], [[2ocj]], [[2ybg<ins style="font-weight: bold; text-decoration: none;">]], [[8f2h]], [8f2i</ins>]] – h-p53 DBD – human&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[2pcx]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[1uol]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[2pcx]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[1uol]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]], [[7dhy]], [[7dhz<ins style="font-weight: bold; text-decoration: none;">]], [[7eax]], [[7eeu]], [[7v97]], [[8e7a]], [[8e7b</ins>]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2ioi]], [[2ioo]], [[1hu8]] – m-p53 DBD – mouse&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2ioi]], [[2ioo]], [[1hu8]] – m-p53 DBD – mouse&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1t4w]] – p53-like DBD – &#039;&#039;Caenoharbditis elegans&#039;&#039;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1t4w]] – p53-like DBD – &#039;&#039;Caenoharbditis elegans&#039;&#039;</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l12">Line 12:</td> <td colspan="2" class="diff-lineno">Line 12:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3igk]], [[3igl]], [[3kz8]], [[3kmd]], [[2ac0]], [[2ady]], [[2ahi]], [[2ata]], [[1tsr]], [[1tup]], [[4hje]], [[5bua]], [[6fj5]], [[5mg7]], [[5mf7]], [[5mcw]], [[5mcu]], [[5mct]], [[5lgy]] – h-p53 DBD + DNA&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3igk]], [[3igl]], [[3kz8]], [[3kmd]], [[2ac0]], [[2ady]], [[2ahi]], [[2ata]], [[1tsr]], [[1tup]], [[4hje]], [[5bua]], [[6fj5]], [[5mg7]], [[5mf7]], [[5mcw]], [[5mcu]], [[5mct]], [[5lgy]] – h-p53 DBD + DNA&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[3d0a]], [[3ts8]], [[4ibu]], [[4ibv]], [[4ibw]] - h-p53 DBD (mutant) + DNA&lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[3d0a]], [[3ts8]], [[4ibu]], [[4ibv]], [[4ibw<ins style="font-weight: bold; text-decoration: none;">]], [[7b47]], [[7b48]], [[7b49]], [[7b4a]], [[7b4b]], [[7b4c]], [[7b4d]], [[7b4e]], [[7b4f]], [[7b4h]], [[7b4n]], [[7eds</ins>]] - h-p53 DBD (mutant) + DNA&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3q05]], [[3q06]] - h-p53 DBD + TD + DNA&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3q05]], [[3q06]] - h-p53 DBD + TD + DNA&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3exj]], [[3exl]], [[2p52]], [[2geq]] – m-p53 DBD + DNA</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[3exj]], [[3exl]], [[2p52]], [[2geq]] – m-p53 DBD + DNA</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l19">Line 19:</td> <td colspan="2" class="diff-lineno">Line 19:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2x0u]], [[2x0v]], [[2x0w]], [[4agl]], [[4agm]], [[4agn]], [[4ago]], [[4agp]], [[4agq]], [[5aol]], [[5aoj]] – h-p53 DBD (mutant) + benzene derivative&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2x0u]], [[2x0v]], [[2x0w]], [[4agl]], [[4agm]], [[4agn]], [[4ago]], [[4agp]], [[4agq]], [[5aol]], [[5aoj]] – h-p53 DBD (mutant) + benzene derivative&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[3zme]] - h-p53 DBD (mutant) + pyrazol derivative&lt;br /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[3zme<ins style="font-weight: bold; text-decoration: none;">]], [[8a92</ins>]] - h-p53 DBD (mutant) + pyrazol derivative<ins style="font-weight: bold; text-decoration: none;">&lt;br /&gt;</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>**[[5aoi]], [[5ab9]] - h-p53 DBD (mutant) + indole derivative&lt;br /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8dc4]] - h-p53 DBD (mutant) + carbazole</ins>&lt;br /&gt;</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[5aoi]], [[5ab9<ins style="font-weight: bold; text-decoration: none;">]], [[8dc6]], [[8dc7]], [[8dc8</ins>]] - h-p53 DBD (mutant) + indole derivative&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2vuk]] - h-p53 DBD + drug&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2vuk]] - h-p53 DBD + drug&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[5g4o]], [[5g4n]], [[5g4m]], [[5aom]], [[5aok]], [[5aba]], [[5a7b]], [[5o1i]], [[5o1h]], [[5o1g]], [[5o1f]], [[5o1e]], [[5o1a]], [[5o1b]], [[5o1c]], [[5o1d]] - h-p53 DBD (mutant) + drug&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[5g4o]], [[5g4n]], [[5g4m]], [[5aom]], [[5aok]], [[5aba]], [[5a7b]], [[5o1i]], [[5o1h]], [[5o1g]], [[5o1f]], [[5o1e]], [[5o1a]], [[5o1b]], [[5o1c]], [[5o1d]] - h-p53 DBD (mutant) + drug&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>**[[6gff]], [[6gge]], [[6ggd]], [[6ggc]], [[6ggb]], [[6gga]], [[6si3]], [[6si4]] - h-p53 DBD (mutant) + stabilizer&lt;br /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**[[6gff]], [[6gge]], [[6ggd]], [[6ggc]], [[6ggb]], [[6gga]], [[6si3]], [[6si4<ins style="font-weight: bold; text-decoration: none;">]], [[8a31]], [[8a32</ins>]] - h-p53 DBD (mutant) + stabilizer&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2iom]] - m-p53 DBD + propanol</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2iom]] - m-p53 DBD + propanol</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l36">Line 36:</td> <td colspan="2" class="diff-lineno">Line 37:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[6rz3]] - h-p53 DBD + IASPP&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[6rz3]] - h-p53 DBD + IASPP&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[7dvd]] - h-p53 DBD + PUMA&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[7dvd]] - h-p53 DBD + PUMA&lt;br /&gt;</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[8hll]], [[8hlm]], [[8hln]] - h-p53 DBD + Bcl-2&lt;br /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[7ygi]] - h-p53 DBD + azurin&lt;br /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 transactivation domain (residues 15-29)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 transactivation domain (residues 15-29)</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l42">Line 42:</td> <td colspan="2" class="diff-lineno">Line 45:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1ycq]], [[1ycr]] - h-p53 TAD + MDM2 protein&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1ycq]], [[1ycr]] - h-p53 TAD + MDM2 protein&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2l14]] – h-p53 TAD + CREB-binding protein&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2l14]] – h-p53 TAD + CREB-binding protein&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2gs0]] – h-p53 TAD + RNA polymerase II transcription factor</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2gs0]] – h-p53 TAD + RNA polymerase II transcription factor<ins style="font-weight: bold; text-decoration: none;">&lt;br /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[7nmi]] - h-p53 TAD + S110P/ANXA2&lt;br /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 tetramerization domain (residues 326-356)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 tetramerization domain (residues 326-356)</div></td></tr> </table> Michal Harel https://proteopedia.org/index.php?title=P53_3D_structures&diff=3485201&oldid=prev Michal Harel at 09:40, 2 December 2021 2021-12-02T09:40:16Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 09:40, 2 December 2021</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5">Line 5:</td> <td colspan="2" class="diff-lineno">Line 5:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2xwr]], [[2ocj]], [[2ybg]] – h-p53 DBD – human&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2xwr]], [[2ocj]], [[2ybg]] – h-p53 DBD – human&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2fej]] - h-p53 DBD - NMR&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[2pcx]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[1uol]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>** [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[2pcx]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[1uol]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4mzi]], [[5lap]], [[6ff9]], [[6shz]], [[6si0]], [[6si1]], [[6sl6<ins style="font-weight: bold; text-decoration: none;">]], [[7dhy]], [[7dhz</ins>]] - h-p53 DBD (mutant) &lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2ioi]], [[2ioo]], [[1hu8]] – m-p53 DBD – mouse&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2ioi]], [[2ioo]], [[1hu8]] – m-p53 DBD – mouse&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1t4w]] – p53-like DBD – &#039;&#039;Caenoharbditis elegans&#039;&#039;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1t4w]] – p53-like DBD – &#039;&#039;Caenoharbditis elegans&#039;&#039;</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l35">Line 35:</td> <td colspan="2" class="diff-lineno">Line 35:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[4qo1]] - h-p53 DBD + nanobody&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[4qo1]] - h-p53 DBD + nanobody&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[6rz3]] - h-p53 DBD + IASPP&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[6rz3]] - h-p53 DBD + IASPP&lt;br /&gt;</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[7dvd]] - h-p53 DBD + PUMA&lt;br /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 transactivation domain (residues 15-29)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 transactivation domain (residues 15-29)</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l48">Line 48:</td> <td colspan="2" class="diff-lineno">Line 49:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1c26]], [[1aie]] - h-p53 TD&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[1c26]], [[1aie]] - h-p53 TD&lt;BR /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2j10]], [[2j11]], [[1a1u]] - h-p53 TD (mutant) – NMR&lt;BR /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[2j10]], [[2j11]], [[1a1u]] - h-p53 TD (mutant) – NMR&lt;BR /&gt;</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[7bwn]] - h-p53 TD + GFP&lt;br /&gt;</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 tetramerization+DBD domains</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* p53 tetramerization+DBD domains</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l53">Line 53:</td> <td colspan="2" class="diff-lineno">Line 55:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[4mzr]], [[3q01]] – h-p53 + DNA&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>** [[4mzr]], [[3q01]] – h-p53 + DNA&lt;br /&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[5xzc]] – h-p53 + P300 – Cryo EM&lt;br /&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>**[[5xzc]] – h-p53 + P300 – Cryo EM&lt;br /&gt;</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">*p53 full (residues 1-393)</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">**[[6xre]] – h-p53 + RNA polymerase II – Cryo EM&lt;br /&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Topic Page]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Topic Page]]</div></td></tr> </table> Michal Harel