Polycomb complex proteins 3D structures - Revision history

Michal Harel at 09:29, 2 June 2026

2026-06-02T09:29:20Z

← Older revision		Revision as of 09:29, 2 June 2026
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	*BMI-1 or Polycomb group ring finger protein 4 or Pcgf4		*BMI-1 or Polycomb group ring finger protein 4 or Pcgf4

	**[[5fr6]] – hBMI1 residues 121-235 <br />		**[[5fr6]] – hBMI1 residues 121-235 <br />
	**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />		**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />

Michal Harel at 09:28, 2 June 2026

2026-06-02T09:28:21Z

← Older revision		Revision as of 09:28, 2 June 2026
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	{{#tree:id=OrganizedByTopic\|openlevels=0\|		{{#tree:id=OrganizedByTopic\|openlevels=0\|

	* Polycomb group ring finger protein 1 or Pcgf1		*Polycomb group ring finger protein 1 or Pcgf1

	**[[4hpm]] – hPcgf1 167-255 + BCORL1 - human<br />		**[[4hpm]] – hPcgf1 167-255 + BCORL1 - human<br />
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	**[[5jh5]] – hPcgf1 + lysine-specific demethylase + S-phase kinase associated protein 1<br />		**[[5jh5]] – hPcgf1 + lysine-specific demethylase + S-phase kinase associated protein 1<br />

	* BMI-1 or Polycomb group ring finger protein 4 or Pcgf4		*BMI-1 or Polycomb group ring finger protein 4 or Pcgf4

	**[[5fr6]] – hBMI1 residues 121-235 <br />		**[[5fr6]] – hBMI1 residues 121-235 <br />
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	**[[8h1t]] – DmAsXL1 + BAP1 + chromatosome – Cryo EM<br />		**[[8h1t]] – DmAsXL1 + BAP1 + chromatosome – Cryo EM<br />

	*Polycomb-like protein 1 or PHD finger protein 1 or HPCL1 or		*Polycomb-like protein 1 or PHD finger protein 1 or HPCL1

	**[[6wat]] – hPcL1 <br />		**[[6wat]] – hPcL1 <br />

Michal Harel at 09:24, 2 June 2026

2026-06-02T09:24:33Z

← Older revision		Revision as of 09:24, 2 June 2026
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	**[[7lky]] – hPcL1 TUDOR domain + peptide inhibitor<br />		**[[7lky]] – hPcL1 TUDOR domain + peptide inhibitor<br />
	**[[5oqd]] – DmPcL WINGED-HELIX domain 491-694<br />		**[[5oqd]] – DmPcL WINGED-HELIX domain 491-694<br />
			}}
	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 09:23, 2 June 2026

2026-06-02T09:23:20Z

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Michal Harel at 09:35, 4 September 2023

2023-09-04T09:35:59Z

← Older revision		Revision as of 09:35, 4 September 2023
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	**[[5fr6]] – hBMI1 residues 121-235 <br />		**[[5fr6]] – hBMI1 residues 121-235 <br />
	**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />		**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />
	**[[6wi7]], [[~~6wi8~~]] – hBMI1 ring domain 1-108/Ring1B <br />		**[[6wi7]], [[8wi8]] – hBMI1 ring domain 1-108/Ring1B <br />
	**[[7nd1]] – hBMI1 ring domain + Ring1B - NMR<br />		**[[7nd1]] – hBMI1 ring domain + Ring1B - NMR<br />
	**[[3rpg]] – hBMI1 ring domain + Ring1B + Ubch5C<br />		**[[3rpg]] – hBMI1 ring domain + Ring1B + Ubch5C<br />
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	*Polycomb EED		*Polycomb EED

	**[[~~5wf7~~]], [[~~5bjs~~]], [[~~5vk3~~]] - ~~CtPcG + EZH2/PcG SUZ12 - ''Chaetomium thermophilum''~~<br />		**[[3jpx]], [[3iiw]], [[3iiy]], [[3ij0]], [[3ij1]], [[3jzg]], [[3jzh]], [[3jzn]], [[5fr6]], [[7kxt]] - hPcG <br />
	**[[~~5wfd~~]] - ~~CtPcG + zinc finger containing protein~~ + inhibitor<br />		**[[5u69]], [[5u6d]], [[5u8a]], [[5k0m]], [[5h13]], [[5u5h]], [[5u5k]], [[5u8f]], [[6sfb]], [[6sfc]], [[6w7f]], [[6w7g]], [[6yvi]], [[6yvj]], [[7msb]], [[7msd]], [[7p3c]], [[7p3g]], [[7p3j]], [[7qjg]], [[7qju]], [[7qk4]], [[7si4]], [[7si5]] - hPcG + inhibitor <br />
	**[[~~5wfc~~]] - ~~CtPcG~~ (mutant) + ~~EZH2~~/~~PcG SUZ12~~ + histone peptide ~~+ inhibitor~~<br />		**[[3ijc]] - hPcG (mutant) + inhibitor <br />
	**[[~~5tqr~~]] - ~~CtPcGCP~~ + ~~EZH2~~/~~PCP SUZ12~~ + ~~SAM~~<br />		**[[6v3x]], [[6v3y]] - hPcG + PALI1 peptide<br />
	**[[~~3jzn~~]] - hPcG <br />		**[[3k26]], [[3k27]] - hPcG + histone peptide<br />
	**[[5wg6]] - hPcG + EZH2 <br />		**[[5wp3]] - hPcG + EB22 <br />
			**[[5ttw]] - hPcG + UNC4859 <br />
			**[[5h14]], [[5h15]], [[5h17]], [[5h19]], [[5u5t]], [[5u62]], [[5h25]], [[5gsa]], [[5h24]], [[5wuk]], [[6lo2]] - hPcG + EZH2 peptide + inhibitor <br />
			**[[5wg6]], [[6u4y]] - hPcG + EZH2 <br />
	**[[5ij7]], [[5ij8]], [[4w2r]], [[6b3w]] - hPcG + EZH2 + PcG SUZ12 + inhibitor<br />		**[[5ij7]], [[5ij8]], [[4w2r]], [[6b3w]] - hPcG + EZH2 + PcG SUZ12 + inhibitor<br />
	**[[5ij8]] - hPcG + EZH2 + PcG SUZ12 + inhibitor<br />		**[[5ij8]] - hPcG + EZH2 + PcG SUZ12 + inhibitor<br />
	**[[5ls6]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 K116me3 <br />		**[[5ls6]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 K116me3 <br />
	**[[5hyn]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 K116me3 + histone peptide<br />		**[[5hyn]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 K116me3 + histone peptide<br />
	**[[6c23]], [[6c24]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 substrate + Jumonji + SUZ12 + RBBP4 - Cryo EM<br />		**[[7ktp]] - hPcG + ENX-2 + PcG SUZ12 + RBBP4 - Cryo EM<br />
			**[[7td5]] - hPcG + ENX-2 + PcG SUZ12 + peptide<br />
			**[[6c23]], [[6c24]], [[7kso]], [[7ksr]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 substrate + Jumonji + SUZ12 + RBBP4 - Cryo EM<br />
			**[[6wkr]], [[7at8]] - hPcG in nucleosome complex - Cryo EM<br />
	**[[4x3e]] - hPcG + Jarid2 peptide <br />		**[[4x3e]] - hPcG + Jarid2 peptide <br />
	**[[3jpx]], [[3iiw]], [[3iiy]], [[3ij0]], [[3ij1]], [[3jzg]], [[3jzh]], [[3k26]],[[5fr6]] - hPcG <br />
	**[[5u69]], [[5u6d]], [[5u8a]], [[5k0m]], [[5h13]], [[5u5h]], [[5u5k]], [[5u8f]] - hPcG + inhibitor <br />
	**[[3ijc]] - hPcG (mutant) + inhibitor <br />
	**[[5wp3]] - hPcG + EB22 <br />
	**[[5ttw]] - hPcG + UNC4859 <br />
	**[[5h14]], [[5h15]], [[5h17]], [[5h19]], [[5u5t]], [[5u62]], [[5h25]], [[5gsa]], [[5h24]], [[5wuk]] - hPcG + EZH2 + inhibitor <br />
	**[[1pdq]], [[1pfb]] - DmPcG chromodomain + histone peptide - ''Drosophila melanogaster''<br />		**[[1pdq]], [[1pfb]] - DmPcG chromodomain + histone peptide - ''Drosophila melanogaster''<br />
			**[[5wf7]], [[5bjs]], [[5vk3]] - CtPcG + EZH2/PcG SUZ12 - ''Chaetomium thermophilum''<br />
			**[[5wfd]] - CtPcG + zinc finger containing protein + inhibitor<br />
			**[[5wfc]] - CtPcG (mutant) + EZH2/PcG SUZ12 + histone peptide + inhibitor<br />
			**[[5tqr]] - CtPcGCP + EZH2/PCP SUZ12 + SAM<br />

	*Polycomb SUZ12		*Polycomb SUZ12
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	**[[5wak]] - hPcG + RBBP4 <br />		**[[5wak]] - hPcG + RBBP4 <br />
	**[[5wai]] - hPcG + RBBP4 + Jarid2 + AEPB2 <br />		**[[5wai]] - hPcG + RBBP4 + Jarid2 + AEPB2 <br />
			**[[6nq3]] - hPcG + RBBP4 + Jumonji + Phd finger protein <br />
	**[[2yb8]] - DmPcG + CAF1<br />		**[[2yb8]] - DmPcG + CAF1<br />

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	**[[2r58]], [[2r5a]] - DmPcG (mutant) + methyl-lysine<br />		**[[2r58]], [[2r5a]] - DmPcG (mutant) + methyl-lysine<br />
	**[[2r5m]] - DmPcG (mutant) + peptide <br />		**[[2r5m]] - DmPcG (mutant) + peptide <br />

			*Polycomb ASX

			**[[6cga]], [[6hgc]] - DmPcG 207-340 + calypso <br />

	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 08:42, 9 January 2023

2023-01-09T08:42:36Z

← Older revision		Revision as of 08:42, 9 January 2023
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	**[[2r58]], [[2r5a]] - DmPcG (mutant) + methyl-lysine<br />		**[[2r58]], [[2r5a]] - DmPcG (mutant) + methyl-lysine<br />
	**[[2r5m]] - DmPcG (mutant) + peptide <br />		**[[2r5m]] - DmPcG (mutant) + peptide <br />
			}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 08:41, 9 January 2023

2023-01-09T08:41:31Z

← Older revision		Revision as of 08:41, 9 January 2023
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	==3D structures of polycomb complex proteins==		==3D structures of polycomb complex proteins==

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	**[[5fr6]] – hBMI1 residues 121-235 <br />		**[[5fr6]] – hBMI1 residues 121-235 <br />
	**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />		**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />
	**[[6wi7]], [[~~8wi8~~]] – hBMI1 ring domain 1-108/Ring1B <br />		**[[6wi7]], [[6wi8]] – hBMI1 ring domain 1-108/Ring1B <br />
	**[[7nd1]] – hBMI1 ring domain + Ring1B - NMR<br />		**[[7nd1]] – hBMI1 ring domain + Ring1B - NMR<br />
	**[[3rpg]] – hBMI1 ring domain + Ring1B + Ubch5C<br />		**[[3rpg]] – hBMI1 ring domain + Ring1B + Ubch5C<br />

Michal Harel: New page: ==3D structures of polycomb complex proteins== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| * Polycomb group ri...

2023-01-09T08:41:03Z

New page: ==3D structures of polycomb complex proteins== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| * Polycomb group ri...

New page

==3D structures of polycomb complex proteins==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

* Polycomb group ring finger protein 1 or Pcgf1

**[[4hpm]] – hPcgf1 167-255 + BCORL1 - human 
**[[4hpl]] – hPcgf1 167-255 + BCOR 

* BMI-1 or Polycomb group ring finger protein 4 or Pcgf4

**[[5fr6]] – hBMI1 residues 121-235 
**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR 
**[[6wi7]], [[8wi8]] – hBMI1 ring domain 1-108/Ring1B 
**[[7nd1]] – hBMI1 ring domain + Ring1B - NMR 
**[[3rpg]] – hBMI1 ring domain + Ring1B + Ubch5C 
**[[2ckl]] – mBMI1 ring domain + Ring1B - mouse 
**[[4r8p]] – BMI1 ring domain + Ring1B + Ubch5C + DNA - frog 

* Polycomb group ring finger protein 5 or Pcgf5

**[[4s3o]] – hPcgf5 ring domain 1-108 + Ring1B + Ubch5C 

* Polycomb group ring finger protein 6 or Pcgf

**[[2djb]] – hPcgf6 ring domain - NMR 

*Polycomb EED

**[[5wf7]], [[5bjs]], [[5vk3]] - CtPcG + EZH2/PcG SUZ12 - ''Chaetomium thermophilum'' 
**[[5wfd]] - CtPcG + zinc finger containing protein + inhibitor 
**[[5wfc]] - CtPcG (mutant) + EZH2/PcG SUZ12 + histone peptide + inhibitor 
**[[5tqr]] - CtPcGCP + EZH2/PCP SUZ12 + SAM 
**[[3jzn]] - hPcG 
**[[5wg6]] - hPcG + EZH2 
**[[5ij7]], [[5ij8]], [[4w2r]], [[6b3w]] - hPcG + EZH2 + PcG SUZ12 + inhibitor 
**[[5ij8]] - hPcG + EZH2 + PcG SUZ12 + inhibitor 
**[[5ls6]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 K116me3 
**[[5hyn]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 K116me3 + histone peptide 
**[[6c23]], [[6c24]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 substrate + Jumonji + SUZ12 + RBBP4 - Cryo EM 
**[[4x3e]] - hPcG + Jarid2 peptide 
**[[3jpx]], [[3iiw]], [[3iiy]], [[3ij0]], [[3ij1]], [[3jzg]], [[3jzh]], [[3k26]],[[5fr6]] - hPcG 
**[[5u69]], [[5u6d]], [[5u8a]], [[5k0m]], [[5h13]], [[5u5h]], [[5u5k]], [[5u8f]] - hPcG + inhibitor 
**[[3ijc]] - hPcG (mutant) + inhibitor 
**[[5wp3]] - hPcG + EB22 
**[[5ttw]] - hPcG + UNC4859 
**[[5h14]], [[5h15]], [[5h17]], [[5h19]], [[5u5t]], [[5u62]], [[5h25]], [[5gsa]], [[5h24]], [[5wuk]] - hPcG + EZH2 + inhibitor 
**[[1pdq]], [[1pfb]] - DmPcG chromodomain + histone peptide - ''Drosophila melanogaster'' 

*Polycomb SUZ12

**[[5wak]] - hPcG + RBBP4 
**[[5wai]] - hPcG + RBBP4 + Jarid2 + AEPB2 
**[[2yb8]] - DmPcG + CAF1 

*Polycomb SCMH1

**[[2p0k]] - hPcG 

*Polycomb SFMBT

**[[4c5e]], [[4c5g]], [[4c5h]] - DmPcG + PcG PHO 
**[[5j8y]] - DmPcG + PcG SCM 
**[[3h6z]] - DmPcG + histone peptide 

*Polycomb PCL

**[[2xk0]] - DmPcG tudor domain - NMR 
**[[5oqd]] - DmPcG Phd2 and winged-helix domain 

*Polycomb SCM

**[[2r57]] - DmPcG (mutant) 
**[[2r58]], [[2r5a]] - DmPcG (mutant) + methyl-lysine 
**[[2r5m]] - DmPcG (mutant) + peptide 

[[Category:Topic Page]]

← Older revision		Revision as of 09:41, 29 March 2026
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	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
	{{#tree:id=OrganizedByTopic\|openlevels=0\|		{{#tree:id=OrganizedByTopic\|openlevels=0\|

	* Polycomb group ring finger protein 1 or Pcgf1		* Polycomb group ring finger protein 1 or Pcgf1

	**[[4hpm]] – hPcgf1 167-255 + BCORL1 - human<br />		**[[4hpm]] – hPcgf1 167-255 + BCORL1 - human<br />
	**[[4hpl]] – hPcgf1 167-255 + BCOR<br />		**[[4hpl]] – hPcgf1 167-255 + BCOR<br />

	* BMI-1 or Polycomb group ring finger protein 4 or Pcgf4		* BMI-1 or Polycomb group ring finger protein 4 or Pcgf4

	**[[5fr6]] – hBMI1 residues 121-235 <br />		**[[5fr6]] – hBMI1 residues 121-235 <br />
	**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />		**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />
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	**[[2ckl]] – mBMI1 ring domain + Ring1B - mouse<br />		**[[2ckl]] – mBMI1 ring domain + Ring1B - mouse<br />
	**[[4r8p]] – BMI1 ring domain + Ring1B + Ubch5C + DNA - frog<br />		**[[4r8p]] – BMI1 ring domain + Ring1B + Ubch5C + DNA - frog<br />

	* Polycomb group ring finger protein 5 or Pcgf5		* Polycomb group ring finger protein 5 or Pcgf5

	**[[4s3o]] – hPcgf5 ring domain 1-108 + Ring1B + Ubch5C<br />		**[[4s3o]] – hPcgf5 ring domain 1-108 + Ring1B + Ubch5C<br />

	* Polycomb group ring finger protein 6 or Pcgf		* Polycomb group ring finger protein 6 or Pcgf

	**[[2djb]] – hPcgf6 ring domain - NMR<br />		**[[2djb]] – hPcgf6 ring domain - NMR<br />

	*Polycomb EED		*Polycomb EED

	**[[3jpx]], [[3iiw]], [[3iiy]], [[3ij0]], [[3ij1]], [[3jzg]], [[3jzh]], [[3jzn]], [[5fr6]], [[7kxt]] - hPcG <br />		**[[3jpx]], [[3iiw]], [[3iiy]], [[3ij0]], [[3ij1]], [[3jzg]], [[3jzh]], [[3jzn]], [[5fr6]], [[7kxt]] - hPcG <br />
	**[[5u69]], [[5u6d]], [[5u8a]], [[5k0m]], [[5h13]], [[5u5h]], [[5u5k]], [[5u8f]], [[6sfb]], [[6sfc]], [[6w7f]], [[6w7g]], [[6yvi]], [[6yvj]], [[7msb]], [[7msd]], [[7p3c]], [[7p3g]], [[7p3j]], [[7qjg]], [[7qju]], [[7qk4]], [[7si4]], [[7si5]] - hPcG + inhibitor <br />		**[[5u69]], [[5u6d]], [[5u8a]], [[5k0m]], [[5h13]], [[5u5h]], [[5u5k]], [[5u8f]], [[6sfb]], [[6sfc]], [[6w7f]], [[6w7g]], [[6yvi]], [[6yvj]], [[7msb]], [[7msd]], [[7p3c]], [[7p3g]], [[7p3j]], [[7qjg]], [[7qju]], [[7qk4]], [[7si4]], [[7si5]] - hPcG + inhibitor <br />
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	**[[5wfc]] - CtPcG (mutant) + EZH2/PcG SUZ12 + histone peptide + inhibitor<br />		**[[5wfc]] - CtPcG (mutant) + EZH2/PcG SUZ12 + histone peptide + inhibitor<br />
	**[[5tqr]] - CtPcGCP + EZH2/PCP SUZ12 + SAM<br />		**[[5tqr]] - CtPcGCP + EZH2/PCP SUZ12 + SAM<br />

	*Polycomb SUZ12		*Polycomb SUZ12

	**[[5wak]] - hPcG + RBBP4 <br />		**[[5wak]] - hPcG + RBBP4 <br />
	**[[5wai]] - hPcG + RBBP4 + Jarid2 + AEPB2 <br />		**[[5wai]] - hPcG + RBBP4 + Jarid2 + AEPB2 <br />
	**[[6nq3]] - hPcG + RBBP4 + Jumonji + Phd finger protein <br />		**[[6nq3]] - hPcG + RBBP4 + Jumonji + Phd finger protein <br />
	**[[2yb8]] - DmPcG + CAF1<br />		**[[2yb8]] - DmPcG + CAF1<br />

	*Polycomb SCMH1		*Polycomb SCMH1

	**[[2p0k]] - hPcG <br />		**[[2p0k]] - hPcG <br />

	*Polycomb SFMBT		*Polycomb SFMBT

	**[[4c5e]], [[4c5g]], [[4c5h]] - DmPcG + PcG PHO <br />		**[[4c5e]], [[4c5g]], [[4c5h]] - DmPcG + PcG PHO <br />
	**[[5j8y]] - DmPcG + PcG SCM <br />		**[[5j8y]] - DmPcG + PcG SCM <br />
	**[[3h6z]] - DmPcG + histone peptide <br />		**[[3h6z]] - DmPcG + histone peptide <br />

	*Polycomb PCL		*Polycomb PCL

	**[[2xk0]] - DmPcG tudor domain - NMR <br />		**[[2xk0]] - DmPcG tudor domain - NMR <br />
	**[[5oqd]] - DmPcG Phd2 and winged-helix domain <br />		**[[5oqd]] - DmPcG Phd2 and winged-helix domain <br />

	*Polycomb SCM		*Polycomb SCM

	**[[2r57]] - DmPcG (mutant) <br />		**[[2r57]] - DmPcG (mutant) <br />
	**[[2r58]], [[2r5a]] - DmPcG (mutant) + methyl-lysine<br />		**[[2r58]], [[2r5a]] - DmPcG (mutant) + methyl-lysine<br />
	**[[2r5m]] - DmPcG (mutant) + peptide <br />		**[[2r5m]] - DmPcG (mutant) + peptide <br />

	*Polycomb ASX		*Polycomb ASX

	**[[6cga]], [[6hgc]] - DmPcG 207-340 + calypso <br />		**[[6cga]], [[6hgc]] - DmPcG 207-340 + calypso <br />