Pyruvate dehydrogenase 3D structures - Revision history

Michal Harel at 09:46, 27 August 2026

2026-08-27T09:46:29Z

← Older revision		Revision as of 09:46, 27 August 2026
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	**[[8oqj]] - EcPDH E2 PSB <br />		**[[8oqj]] - EcPDH E2 PSB <br />
	**[[1w4i]], [[1w4j]], [[1w4k]] - PaPDH E2 PSB - NMR<br />		**[[1w4i]], [[1w4j]], [[1w4k]] - PaPDH E2 PSB - NMR<br />
	**[[1eaa]], [[1eab]], [[1eac]], [[1ead]], [[1eae]], [[1eaf]] – AvPDH E2 catalytic domain – Azotobacter vinelandii<br />		**[[1eaa]], [[1eab]], [[1eac]], [[1ead]], [[1eae]], [[1eaf]] – AvPDH E2 catalytic domain – ''Azotobacter vinelandii''<br />
	**[[1iyu]], [[1iyv]] – AvPDH E2 1-79 – NMR<br />		**[[1iyu]], [[1iyv]] – AvPDH E2 1-79 – NMR<br />
	**[[6zzi]], [[6zzm]] – CmPDH E2 catalytic domain – Corynebacterium mustelae<br />		**[[6zzi]], [[6zzm]] – CmPDH E2 catalytic domain – ''Corynebacterium mustelae''<br />
	**[[6zzj]] – CmPDH E2 catalytic domain + acetylCoA<br />		**[[6zzj]] – CmPDH E2 catalytic domain + acetylCoA<br />
	**[[6zzl]] – CgPDH E2 catalytic domain - Corynebacterium glutamicum<br />		**[[6zzl]] – CgPDH E2 catalytic domain - Corynebacterium glutamicum<br />

Michal Harel at 09:44, 27 August 2026

2026-08-27T09:44:48Z

← Older revision		Revision as of 09:44, 27 August 2026
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	**[[4qoy]] - EcPDH E1 + PDH E2<br />		**[[4qoy]] - EcPDH E1 + PDH E2<br />

	*Pyruvate dehydrogenase E2 ~~domain~~ see [[Dihydrolipoyl transacetylase]] and [[Dihydrolipoamide acetyltransferase]]		*Pyruvate dehydrogenase E2 see [[Dihydrolipoyl transacetylase]] and [[Dihydrolipoamide acetyltransferase]]; Domains – peripheral-subunit binding (PSB) 118-170; lipoyl 179-282; catalytic 395-697
	**[[7bgj]], [[7q5r]] – PDH E2 – ''Thermochaetoides thermophila'' – ~~Cryo EM<br />~~

	*~~Pyruvate dehydrogenase E1~~+E2 ~~domains~~		**[[3b8k]], [[6ct0]], [[8piu]] – hPDH E2 – Cryo EM<br />
			**[[7uom]] – hPDH E2 catalytic domain – Cryo EM<br />
			**[[8x03]] – PDH E2 – bovine - Cryo EM<br />
			**[[8x03]], [[9j1w]] – PDH E2 – pig - Cryo EM<br />
			**[[7bgj]], [[7ott]], [[7q5r]] – PDH E2 – ''Thermochaetoides thermophila'' – Cryo EM<br />
			**[[7b9k]], [[8orb]] – EcPDH E2 catalytic domain – Cryo EM<br />
			**[[4n72]], [[8osy]] – EcPDH E2 catalytic domain <br />
			**[[1fyc]], [[1qjo]], [[2k7v]] – EcPDH E2 lipoyl domain - NMR<br />
			**[[8oqj]] - EcPDH E2 PSB <br />
			**[[1w4i]], [[1w4j]], [[1w4k]] - PaPDH E2 PSB - NMR<br />
			**[[1eaa]], [[1eab]], [[1eac]], [[1ead]], [[1eae]], [[1eaf]] – AvPDH E2 catalytic domain – Azotobacter vinelandii<br />
			**[[1iyu]], [[1iyv]] – AvPDH E2 1-79 – NMR<br />
			**[[6zzi]], [[6zzm]] – CmPDH E2 catalytic domain – Corynebacterium mustelae<br />
			**[[6zzj]] – CmPDH E2 catalytic domain + acetylCoA<br />
			**[[6zzl]] – CgPDH E2 catalytic domain - Corynebacterium glutamicum<br />
			**[[6zzk]] – CgPDH E2 catalytic domain + acetylCoA + dihydropolyamide <br />
			**[[9y6t]], [[9y72]] – MtPDH E2 catalytic domain – Mycobacterium tuberculosis – Cryo EM<br />
			**[[9y7v]] – MtPDH E2 catalytic domain + acetylCoA – Cryo EM<br />
			**[[9ukz]] - BsPDH E2 catalytic domain – ''Bacillus stearothermophilus'' – Cryo EM<br />
			**[[1w3d]], [[2pdd]], [[2pde]] - BsPDH E2 PSB - NMR<br />
			**[[1lab]], [[1lac]] – BsPDH E2 lipoyl domain - NMR<br />

	**[[1w85]], [[1w88]] - BsPDH E1 α + β subunits + PDH E2 peripheral-subunit binding domain ~~– ''Bacillus stearothermophilus''~~<br />		*Pyruvate dehydrogenase E1+E2

			**[[1w85]], [[1w88]] - BsPDH E1 α + β subunits + PDH E2 peripheral-subunit binding domain <br />
	**[[3duf]], [[3dv0]] - BsPDH E1 α + β subunits + PDH E2<br />		**[[3duf]], [[3dv0]] - BsPDH E1 α + β subunits + PDH E2<br />
	**[[3dva]] - BsPDH E1 α (mutant) + β subunits + PDH E2<br />		**[[3dva]] - BsPDH E1 α (mutant) + β subunits + PDH E2<br />
			**[[9h1n]] - EcPDH E1 2-50 + PDH E2 315-380<br />

	*Pyruvate dehydrogenase E3 ~~domain~~		*Pyruvate dehydrogenase E3 or dihydrolipoyl dehydrogenase

	**[[6h60]] – hPDH protein X – Cryo EM<br />		**[[6h60]] – hPDH protein X – Cryo EM<br />
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	**[[2g25]] - hPDH protein X + phosphonolactylthiamin diphosphate<BR />		**[[2g25]] - hPDH protein X + phosphonolactylthiamin diphosphate<BR />
	**[[2g28]] - hPDH protein X (mutant) + phosphonolactylthiamin diphosphate<br />		**[[2g28]] - hPDH protein X (mutant) + phosphonolactylthiamin diphosphate<br />
	**[[~~2eq6~~]] – TtPDH E3 – ''Thermus thermophilus''<BR />		**[[2eq8]] – TtPDH E3 – ''Thermus thermophilus''<BR />
	**[[4jdr]] – EcPDH E3<br />		**[[4jdr]], [[4jq9]] – EcPDH E3<br />
	**[[1gjx]] – PDH E3 lipoyl domain – ''Neisseria meningitis'' – NMR<br />		**[[1gjx]] – PDH E3 lipoyl domain – ''Neisseria meningitis'' – NMR<br />
	**[[6zlm]] – ~~PDH~~ protein X ~~in PDH complex~~ – ''Neurospora crassa'' - Cryo EM<br />		**[[6zlm]], [[6zlo]], [[7r5m]], [[8ohs]] – NcPDH protein X + E2 – ''Neurospora crassa'' - Cryo EM<br />

			*Pyruvate dehydrogenase E2+E3

			**[[9h2i]] - EcPDH E2 catalytic domain + PDH E3 <br />
	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 09:13, 4 October 2023

2023-10-04T09:13:55Z

← Older revision		Revision as of 09:13, 4 October 2023
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	*Pyruvate dehydrogenase E2 domain see [[Dihydrolipoyl transacetylase]] and [[Dihydrolipoamide acetyltransferase]]		*Pyruvate dehydrogenase E2 domain see [[Dihydrolipoyl transacetylase]] and [[Dihydrolipoamide acetyltransferase]]
			**[[7bgj]], [[7q5r]] – PDH E2 – ''Thermochaetoides thermophila'' – Cryo EM<br />

	*Pyruvate dehydrogenase E1+E2 domains		*Pyruvate dehydrogenase E1+E2 domains

Michal Harel at 08:16, 9 February 2022

2022-02-09T08:16:55Z

← Older revision		Revision as of 08:16, 9 February 2022
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	**[[6h60]] – hPDH protein X – Cryo EM<br />		**[[6h60]] – hPDH protein X – Cryo EM<br />
	**[[1zy8]] – hPDH protein X + dihydrolipoyl dehydrogenase<BR />		**[[1zy8]] – hPDH protein X + dihydrolipoyl dehydrogenase<BR />
	**[[6zlm]] – hPDH protein X + dihydrolipoyl dehydrogenase - Cryo EM<BR />
	**[[2f5z]] - hPDH protein X (mutant) + dihydrolipoyl dehydrogenase<BR />		**[[2f5z]] - hPDH protein X (mutant) + dihydrolipoyl dehydrogenase<BR />
	**[[2f60]] - hPDH protein X (mutant) <BR />		**[[2f60]] - hPDH protein X (mutant) <BR />
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	**[[4jdr]] – EcPDH E3<br />		**[[4jdr]] – EcPDH E3<br />
	**[[1gjx]] – PDH E3 lipoyl domain – ''Neisseria meningitis'' – NMR<br />		**[[1gjx]] – PDH E3 lipoyl domain – ''Neisseria meningitis'' – NMR<br />
			**[[6zlm]] – PDH protein X in PDH complex – ''Neurospora crassa'' - Cryo EM<br />

	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 07:15, 14 October 2020

2020-10-14T07:15:47Z

Michal Harel: New page: ==3D structures of pyruvate dehydrogenase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Pyruvate dehydrogenase...

2019-12-05T11:19:12Z

New page: ==3D structures of pyruvate dehydrogenase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Pyruvate dehydrogenase...

New page

==3D structures of pyruvate dehydrogenase==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

*Pyruvate dehydrogenase E1 domain

**[[3exe]] - hPDH E1 α + β subunits - human 
**[[1ni4]], [[6cfo]] – hPDH E1 α + β (mutant) subunits 
**[[2ozl]], [[3exg]], [[3exh]], [[3exi]], [[6cer]] - hPDH E1 α (mutant) + β subunits 
**[[1ik6]] – PaPDH E1 β subunit – ''Pyrobaculum aerophilum'' 
**[[1l8a]], [[2g25]], [[2g67]], [[2iea]] – EcPDH E1 – ''Escherichia coli'' 
**[[3ey9]], [[3eya]] – EcPDH (cytochrome) 
**[[2qta]], [[3lpl]], [[3lq2]], [[3lq4]] - EcPDH E1 (mutant) 
**[[2qtc]] - EcPDH E1 (mutant) + phosphonolactylthiamin diphosphate 
**[[1rp7]] - EcPDH E1 + inhibitor 
**[[4qoy]] - EcPDH E1 + PDH E2 
**[[3exf]] - hPDH E1 α (mutant) + β subunits + TDP

*Pyruvate dehydrogenase E2 domain see [[Dihydrolipoyl transacetylase]] and [[Dihydrolipoamide acetyltransferase]]

*Pyruvate dehydrogenase E1+E2 domains

**[[1w85]], [[1w88]] - BsPDH E1 α + β subunits + PDH E2 peripheral-subunit binding domain – ''Bacillus stearothermophilus'' 
**[[3duf]], [[3dv0]] - BsPDH E1 α + β subunits + PDH E2 
**[[3dva]] - BsPDH E1 α (mutant) + β subunits + PDH E2 

*Pyruvate dehydrogenase E3 domain

**[[6h60]] – hPDH protein X – Cryo EM 
**[[1zy8]] – hPDH protein X + dihydrolipoyl dehydrogenase 
**[[2f5z]] - hPDH protein X (mutant) + dihydrolipoyl dehydrogenase 
**[[2f60]] - hPDH protein X (mutant) 
**[[2dnc]], [[2dne]] - hPDH protein X N terminal - NMR 
**[[2g25]] - hPDH protein X + phosphonolactylthiamin diphosphate 
**[[2g28]] - hPDH protein X (mutant) + phosphonolactylthiamin diphosphate 
**[[2eq6]] – TtPDH E3 – ''Thermus thermophilus'' 
**[[4jdr]] – EcPDH E3 
**[[1gjx]] – PDH E3 lipoyl domain – ''Neisseria meningitis'' – NMR 

}}

[[Category:Topic Page]]

← Older revision		Revision as of 07:15, 14 October 2020
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	**[[1ni4]], [[6cfo]] – hPDH E1 α + β (mutant) subunits <BR />		**[[1ni4]], [[6cfo]] – hPDH E1 α + β (mutant) subunits <BR />
	**[[2ozl]], [[3exg]], [[3exh]], [[3exi]], [[6cer]] - hPDH E1 α (mutant) + β subunits<BR />		**[[2ozl]], [[3exg]], [[3exh]], [[3exi]], [[6cer]] - hPDH E1 α (mutant) + β subunits<BR />
			**[[3exf]] - hPDH E1 α (mutant) + β subunits + TDP<br />
	**[[1ik6]] – PaPDH E1 β subunit – ''Pyrobaculum aerophilum''<BR />		**[[1ik6]] – PaPDH E1 β subunit – ''Pyrobaculum aerophilum''<BR />
	**[[1l8a]], [[2g25]], [[2g67]], [[2iea]] – EcPDH E1 – ''Escherichia coli''<BR />		**[[1l8a]], [[2g25]], [[2g67]], [[2iea]] – EcPDH E1 – ''Escherichia coli''<BR />
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	**[[1rp7]] - EcPDH E1 + inhibitor<BR />		**[[1rp7]] - EcPDH E1 + inhibitor<BR />
	**[[4qoy]] - EcPDH E1 + PDH E2<br />		**[[4qoy]] - EcPDH E1 + PDH E2<br />
	**[[3exf]] - hPDH E1 α (mutant) + β subunits + TDP

	*Pyruvate dehydrogenase E2 domain see [[Dihydrolipoyl transacetylase]] and [[Dihydrolipoamide acetyltransferase]]		*Pyruvate dehydrogenase E2 domain see [[Dihydrolipoyl transacetylase]] and [[Dihydrolipoamide acetyltransferase]]
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	**[[6h60]] – hPDH protein X – Cryo EM<br />		**[[6h60]] – hPDH protein X – Cryo EM<br />
	**[[1zy8]] – hPDH protein X + dihydrolipoyl dehydrogenase<BR />		**[[1zy8]] – hPDH protein X + dihydrolipoyl dehydrogenase<BR />
			**[[6zlm]] – hPDH protein X + dihydrolipoyl dehydrogenase - Cryo EM<BR />
	**[[2f5z]] - hPDH protein X (mutant) + dihydrolipoyl dehydrogenase<BR />		**[[2f5z]] - hPDH protein X (mutant) + dihydrolipoyl dehydrogenase<BR />
	**[[2f60]] - hPDH protein X (mutant) <BR />		**[[2f60]] - hPDH protein X (mutant) <BR />