Thrombin 3D Structures - Revision history

Michal Harel at 08:30, 19 August 2024

2024-08-19T08:30:18Z

← Older revision		Revision as of 08:30, 19 August 2024
Line 25:		Line 25:
	**[[2h9t]] - hThr HC + LC + suramin + PPACK<BR />		**[[2h9t]] - hThr HC + LC + suramin + PPACK<BR />
	**[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />		**[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />
	**[[1b7x]], [[1sfq]], [[1shh]], [[1thp]], [[2thf]], [[4rko]] - hThr HC (mutant) + LC + PPACK<BR />		**[[1b7x]], [[1sfq]], [[1shh]], [[1thp]], [[2thf]], [[2pgq]],[[4rko]] - hThr HC (mutant) + LC + PPACK<BR />
	**[[1ook]], [[6v64]] - hThr HC + LC + PPACK<BR />		**[[1ook]], [[6v64]] - hThr HC + LC + PPACK<BR />
			**[[6gwe]], [[6t7h]] - hThr HC + LC + macrocycle<br />
			**[[5cmx]], [[5ew1]], [[5ew2]] - hThr HC + LC + DNA<br />
			**[[5do4]] - hThr HC + LC + RNA<br />
	**[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />		**[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />
	**[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />		**[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />
Line 42:		Line 45:
	**[[1eoj]], [[1eol]], [[1g37]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br />		**[[1eoj]], [[1eol]], [[1g37]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br />
	**[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br />		**[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br />
			**[[3qdz]] - hThr HC (mutant) + LC + PAR4 peptide<br />
	**[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide <br />		**[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide <br />
	**[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor<br />		**[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor<br />
Line 82:		Line 86:
	**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />		**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />
	**[[3b23]] - hThr HC + LC + variegin<br />		**[[3b23]] - hThr HC + LC + variegin<br />
			**[[1id5]] - hThr HC + LC + ecotin<br />
	**[[6tkh]], [[6tki]], [[6tkj]] - hThr HC + LC + tsetse Thr inhibitor<br />		**[[6tkh]], [[6tki]], [[6tkj]] - hThr HC + LC + tsetse Thr inhibitor<br />
	**[[5e8e]] - hThr HC + LC + antibody<br />		**[[5e8e]] - hThr HC + LC + antibody<br />
Line 92:		Line 97:
	*'''Prothrombin'''		*'''Prothrombin'''

	**[[2afq~~]], [[3e6p~~]], [[3u69~~]], [[6v5t~~]] - hPThr HC + LC<br />		**[[2afq]], [[3u69]] - hPThr HC + LC<br />
	**[[3s7h]], [[3s7k]], [[6p9u]] – hPThr HC + LC (mutant) <br />		**[[3s7h]], [[3s7k]], [[6p9u]] – hPThr HC + LC (mutant) <br />
	**[[1rd3]], [[1tq0]], [[2gp9]], [[2pgb]], [[3bei]], [[4h6s]], [[4h6t]], [[4hzh]], [[6bjr]], [[6c2w]] - hPThr HC (mutant) + LC<br />		**[[1rd3]], [[1tq0]], [[2gp9]], [[2pgb]], [[3bei]], [[4h6s]], [[4h6t]], [[4hzh]], [[6bjr]], [[6c2w]] - hPThr HC (mutant) + LC<br />
Line 101:		Line 106:

	**[[6cym]] - hPThr HC + LC + inhibitor<br />		**[[6cym]] - hPThr HC + LC + inhibitor<br />
	**[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />
	**[[3bef]], [[3lu9]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />		**[[3bef]], [[3lu9]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
	**[[1sr5]] - hPThr HC + LC + antithrombin III<br />		**[[1sr5]] - hPThr HC + LC + antithrombin III<br />
	**[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br />
	**[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />		**[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />
	**[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br />		**[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br />
	**[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br />		**[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br />
	**[[1tq7~~]], [[2pgq~~]] - hPThr HC (mutant) + LC + PPACK<BR />		**[[1tq7]] - hPThr HC (mutant) + LC + PPACK<BR />
	**[[6gwe]], [[6t7h]] - hPThr HC + LC + macrocycle<br />		**[[1g30]], [[1g32]], [[1k21]], [[1k22]], [[1o5g]], [[1sb1]], [[1t4u]], [[1t4v]], [[3tu7]], [[4lxb]], [[5jfd]], [[5jzy]], [[5lce]], [[6eo8]], [[6eo9]] [[6fjt]], [[6gbw]], [[6hsx]], [[6i51]], [[6rot]], [[6t3m]], [[6t3q]], [[6t4a]], [[6t52]], [[6t53]], [[6t54]], [[6t55]], [[6t56]], [[6t57]], [[6t89]], [[6t8a]], [[6tdt]], [[6y02]], [[6y9h]], [[6yb6]], [[6yhg]], [[6yhj]], [[6ymp]], [[6yn3]], [[6yqv]], [[6ysj]], [[6ysx]], [[6zug]], [[6zuh]], [[6zun]], [[6zuu]], [[6zuw]], [[6zux]], [[6zv7]], [[6zv8]] - hPThr HC + LC + hirudin peptide + inhibitor<br />
	**[[1g30]], [[1g32]], [[1k21]], [[1k22]], [[1o5g]], [[1sb1]], [[1t4u]], [[1t4v~~]], [[2cno~~]], [[3tu7]], [[4lxb]], [[5jfd]], [[5jzy]], [[5lce]], [[6eo8]], [[6eo9]] [[6fjt]], [[6gbw]], [[6hsx]], [[6i51]], [[6rot]], [[6t3m]], [[6t3q]], [[6t4a]], [[6t52]], [[6t53]], [[6t54]], [[6t55]], [[6t56]], [[6t57]], [[6t89]], [[6t8a]], [[6tdt]], [[6y02]], [[6y9h]], [[6yb6]], [[6yhg]], [[6yhj]], [[6ymp]], [[6yn3]], [[6yqv]], [[6ysj]], [[6ysx]], [[6zug]], [[6zuh]], [[6zun]], [[6zuu]], [[6zuw]], [[6zux]], [[6zv7]], [[6zv8]] - hPThr HC + LC + hirudin peptide + inhibitor<br />
	**[[4ax9]] - hPThr HC + LC + hirudin peptide<br />		**[[4ax9]] - hPThr HC + LC + hirudin peptide<br />
	**[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />		**[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />
	**[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />		**[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />
	**[[4dii]], [[4i7y~~]], [[5ew1]], [[5ew2]], [[5cmx~~]], [[6eo6]], [[6eo7]], [[6evv]], [[6gn7]], [[6z8v]] - hPThr HC + LC + aptamer~~<br />~~		**[[4dii]], [[4i7y]], [[6eo6]], [[6eo7]], [[6evv]], [[6gn7]], [[6z8v]] - hPThr HC + LC + DNA aptamer<br />
	**[[5do4]] - hPThr HC + LC + RNA<br />
	**[[7a0d]], [[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br />		**[[7a0d]], [[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br />

	*Prothrombin complex with protein		*Prothrombin complex with protein

	**[[1id5]] - hPThr HC + LC + ecotin<br />
	**[[1p8v]] - hPThr HC + LC + platelet glycoprotein IB α chain<br />		**[[1p8v]] - hPThr HC + LC + platelet glycoprotein IB α chain<br />
	**[[3gis]] - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin<br />		**[[3gis]] - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin<br />
Line 129:		Line 129:
	**[[6tkg]], [[6tkl]] - hPThr HC + LC + tsetse Thr inhibitor<br />		**[[6tkg]], [[6tkl]] - hPThr HC + LC + tsetse Thr inhibitor<br />

	*'''Prethrombin-1'''		*'''Prethrombin-1 residues 199-622'''

	**[[3nxp]] - hThr ~~residues 199-622~~		**[[3nxp]] - hThr

	*'''Prethrombin-2'''		*'''Prethrombin-2 residues 328-622'''

			**[[6v5t]] – hThr<br />
	**[[1nu9]] – hThr + staphylocoagulase<br />		**[[1nu9]] – hThr + staphylocoagulase<br />
	**[[1mkw]], [[1mkx]] – hThr + bThr HC + LC<br />		**[[1mkw]], [[1mkx]] – hThr + bThr HC + LC<br />
	**[[1hag]], [[1hah]] – hThr + hirudin peptide<br />		**[[1hag]], [[1hah]] – hThr + hirudin peptide<br />
	**[[1hai]] – hThr + inhibitor<br />		**[[1hai]] – hThr + inhibitor<br />
	**[[3sqe]], [[3sqh]] - hThr (mutant)		**[[3sqe]], [[3sqh]] - hThr (mutant)<br />
			**[[3k65]] - hThr HC residues 315-622 (mutant) + LC residues 199-314<br />

	*'''Meizothrombin'''		*'''Meizothrombin'''

	**[[1a0h]] – bMThr		**[[3e6p]] – hMthr HC 364-622 + LC 206-363
			**[[1a0h]] – bMThr HC 367-625 + LC 208-366

	*'''Saxthrombin'''		*'''Saxthrombin'''

	**[[3s69]] – Thr – ''Gloydis saxatilis''<br />		**[[3s69]] – Thr – Gloydis saxatilis<br />
	}}		}}

	[[Category:Topic Page]]		[[Category:Topic Page]]

Michal Harel at 11:00, 24 December 2023

2023-12-24T11:00:01Z

Show changes

Michal Harel at 10:25, 21 April 2022

2022-04-21T10:25:53Z

← Older revision		Revision as of 10:25, 21 April 2022
Line 8:		Line 8:
	**[[3r3g]], [[3gic]] - hThr HC + LC - human<br />		**[[3r3g]], [[3gic]] - hThr HC + LC - human<br />
	**[[3jz1]], [[3jz2]], [[2od3]], [[6pxq]], [[6pxj]] - hThr HC + LC (mutant) <br />		**[[3jz1]], [[3jz2]], [[2od3]], [[6pxq]], [[6pxj]] - hThr HC + LC (mutant) <br />
			**[[7sr9]] - hThr HC (mutant) + LC (mutant)<br />
	**[[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj]], [[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />		**[[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj]], [[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />
	**[[2hnt]]– hThr-γ HC + LC<br />		**[[2hnt]]– hThr-γ HC + LC<br />
Line 35:		Line 36:
	**[[5gim]] - hPThr HC + LC + peptide<br />		**[[5gim]] - hPThr HC + LC + peptide<br />
	**[[3hkj]] - hThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br />		**[[3hkj]] - hThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br />
			**[[1de7]] - hThr HC + LC + factor XIII activation peptide<br />
	**[[1fph]] - hThr HC + LC + fibrinogen peptide<br />		**[[1fph]] - hThr HC + LC + fibrinogen peptide<br />
	**[[3bv9]] - hThr HC (mutant) + LC + peptide inhibitor<br />		**[[3bv9]] - hThr HC (mutant) + LC + peptide inhibitor<br />
Line 53:		Line 55:

	**[[3c27]], [[2zc9]], [[2zda]], [[2zdv]], [[3egk]], [[2r2m]], [[2v3h]], [[2v3o]], [[2pks]], [[3eq0]], [[3dt0]], [[3dux]], [[3da9]], [[3dhk]], [[2znk]], [[2zo3]], [[3d49]], [[2zhe]], [[2zhf]], [[2zhw]], [[2zg0]], [[2zfq]], [[2zfr]], [[2zhq]], [[2zi2]], [[2ziq]], [[2zff]], [[2zfp]], [[2zgb]], [[2zgx]], [[2zf0]], [[3biu]], [[3biv]], [[2uuj]], [[2uuk]], [[2jh0]], [[2jh5]], [[2jh6]], [[2gde]], [[2bxt]], [[2bxu]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bdy]], [[2feq]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2anm]], [[2w7g]], [[2fes]], [[1ype]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[1vzq]], [[1way]], [[1wbg]], [[1riw]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1oyt]], [[1o2g]], [[1gj4]], [[1gj5]], [[1kts]], [[1ktt]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1c5n]], [[1c5o]], [[1c4y]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1c4u]], [[1c4v]], [[1c1u]], [[1c1v]], [[1c1w]], [[1qj1]], [[1qj6]], [[1qj7]], [[1qhr]], [[1qur]], [[1d4p]], [[1ba8]], [[1bb0]], [[1ca8]], [[1awf]], [[1awh]], [[1bcu]], [[1a61]], [[1a3b]], [[1a3e]], [[1a46]], [[1a5g]], [[1b5g]], [[1tbz]], [[1a4w]], [[1ay6]], [[1ae8]], [[1afe]], [[1ad8]], [[1ai8]], [[1aix]], [[1bmm]], [[1bmn]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1uma]], [[1aht]], [[1fpc]], [[1w7g]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qx5]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]], [[3t5f]], [[3sv2]], [[3si3]], [[3si4]], [[3sha]], [[3shc]], [[3u98]], [[3u9a]], [[3uwj]], [[4e7r]], [[6eo8]], [[6eo9]], [[4loy]] - hThr HC + LC + hirudin peptide + inhibitor<br />		**[[3c27]], [[2zc9]], [[2zda]], [[2zdv]], [[3egk]], [[2r2m]], [[2v3h]], [[2v3o]], [[2pks]], [[3eq0]], [[3dt0]], [[3dux]], [[3da9]], [[3dhk]], [[2znk]], [[2zo3]], [[3d49]], [[2zhe]], [[2zhf]], [[2zhw]], [[2zg0]], [[2zfq]], [[2zfr]], [[2zhq]], [[2zi2]], [[2ziq]], [[2zff]], [[2zfp]], [[2zgb]], [[2zgx]], [[2zf0]], [[3biu]], [[3biv]], [[2uuj]], [[2uuk]], [[2jh0]], [[2jh5]], [[2jh6]], [[2gde]], [[2bxt]], [[2bxu]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bdy]], [[2feq]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2anm]], [[2w7g]], [[2fes]], [[1ype]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[1vzq]], [[1way]], [[1wbg]], [[1riw]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1oyt]], [[1o2g]], [[1gj4]], [[1gj5]], [[1kts]], [[1ktt]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1c5n]], [[1c5o]], [[1c4y]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1c4u]], [[1c4v]], [[1c1u]], [[1c1v]], [[1c1w]], [[1qj1]], [[1qj6]], [[1qj7]], [[1qhr]], [[1qur]], [[1d4p]], [[1ba8]], [[1bb0]], [[1ca8]], [[1awf]], [[1awh]], [[1bcu]], [[1a61]], [[1a3b]], [[1a3e]], [[1a46]], [[1a5g]], [[1b5g]], [[1tbz]], [[1a4w]], [[1ay6]], [[1ae8]], [[1afe]], [[1ad8]], [[1ai8]], [[1aix]], [[1bmm]], [[1bmn]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1uma]], [[1aht]], [[1fpc]], [[1w7g]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qx5]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]], [[3t5f]], [[3sv2]], [[3si3]], [[3si4]], [[3sha]], [[3shc]], [[3u98]], [[3u9a]], [[3uwj]], [[4e7r]], [[6eo8]], [[6eo9]], [[4loy]] - hThr HC + LC + hirudin peptide + inhibitor<br />
			**[[7kme]] – hThr-a HC + LC + hirudin peptide + protein inhibitor<br />
			**[[7ac9]] – hThr HC + LC + hirudin peptide + Arg<br />
	**[[1zgi]], [[1zgv]], [[1zrb]], [[1z71]], [[1xm1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1nm6]], [[1nt1]], [[1doj]], [[1d9i]], [[1d6w]], [[1qbv]], [[1tmu]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]], [[4baq]], [[4bao]], [[4ban]], [[4bak]], [[4bam]], [[4bah]], [[5lpd]], [[5ahg]], [[5afz]], [[5afy]], [[5af9]], [[5a2m]], [[4yes]], [[4ufg]], [[4uff]], [[4ufe]], [[4ufd]], [[4ueh]], [[4ue7]], [[4udw]], [[4ud9]] - hThr HC + hirudin peptide + inhibitor<br />		**[[1zgi]], [[1zgv]], [[1zrb]], [[1z71]], [[1xm1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1nm6]], [[1nt1]], [[1doj]], [[1d9i]], [[1d6w]], [[1qbv]], [[1tmu]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]], [[4baq]], [[4bao]], [[4ban]], [[4bak]], [[4bam]], [[4bah]], [[5lpd]], [[5ahg]], [[5afz]], [[5afy]], [[5af9]], [[5a2m]], [[4yes]], [[4ufg]], [[4uff]], [[4ufe]], [[4ufd]], [[4ueh]], [[4ue7]], [[4udw]], [[4ud9]] - hThr HC + hirudin peptide + inhibitor<br />
	**[[1ny2]], [[8kme]], [[7kme]], [[1a2c]], [[1tom]], [[1hdt]], [[1tmt]], [[1tmb]], [[3u8o]], [[3u8r]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br />		**[[1ny2]], [[8kme]], [[7kme]], [[1a2c]], [[1tom]], [[1hdt]], [[1tmt]], [[1tmb]], [[3u8o]], [[3u8r]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br />
Line 75:		Line 79:
	**[[1dx5]] - hThr HC + LC + thrombomodulin<br />		**[[1dx5]] - hThr HC + LC + thrombomodulin<br />
	**[[3p6z]], [[3p70]] - hThr HC + LC + coagulation factor V<br />		**[[3p6z]], [[3p70]] - hThr HC + LC + coagulation factor V<br />
	**[[~~1de7~~]] - hThr HC + LC + ~~factor XIII activation peptide~~<br />		**[[7mj5]] - hThr HC + LC + XC-43<br />
			**[[7phx]] - hThr HC + LC + tsetse coagulation inhibitor<br />
	**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />		**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />
	**[[3b23]] - hThr HC + LC + variegin<br />		**[[3b23]] - hThr HC + LC + variegin<br />
Line 112:		Line 117:
	**[[4i7y]], [[5ew2]], [[5ew1]], [[5cmx]], [[6eo7]], [[6eo6]], [[6gn7]], [[6evv]] - hPThr HC + LC + DNA<br />		**[[4i7y]], [[5ew2]], [[5ew1]], [[5cmx]], [[6eo7]], [[6eo6]], [[6gn7]], [[6evv]] - hPThr HC + LC + DNA<br />
	**[[5do4]] - hPThr HC + LC + RNA<br />		**[[5do4]] - hPThr HC + LC + RNA<br />
			**[[7a0e]], [[7a0f]] - bPThr + hirudin peptide<br />

	*Prothrombin complex with protein		*Prothrombin complex with protein

Michal Harel at 11:19, 29 November 2020

2020-11-29T11:19:58Z

← Older revision		Revision as of 11:19, 29 November 2020
Line 7:		Line 7:

	**[[3r3g]], [[3gic]] - hThr HC + LC - human<br />		**[[3r3g]], [[3gic]] - hThr HC + LC - human<br />
	**[[3jz1]], [[3jz2]], [[2od3]] - hThr HC + LC (mutant) <br />		**[[3jz1]], [[3jz2]], [[2od3]], [[6pxq]], [[6pxj]] - hThr HC + LC (mutant) <br />
	**[[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj]], [[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />		**[[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj]], [[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />
	**[[2hnt]]– hThr-γ HC + LC<br />		**[[2hnt]]– hThr-γ HC + LC<br />
Line 25:		Line 25:
	**[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />		**[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />
	**[[1sfq]], [[1shh]], [[2thf]], [[1thp]], [[1b7x]], [[4rko]] - hThr HC (mutant) + LC + PPACK<BR />		**[[1sfq]], [[1shh]], [[2thf]], [[1thp]], [[1b7x]], [[4rko]] - hThr HC (mutant) + LC + PPACK<BR />
	**[[1ook]] - hThr HC + LC + PPACK<BR />		**[[1ook]], [[6v64]] - hThr HC + LC + PPACK<BR />
	**[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />		**[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />
	**[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />		**[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />
Line 78:		Line 78:
	**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />		**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />
	**[[3b23]] - hThr HC + LC + variegin<br />		**[[3b23]] - hThr HC + LC + variegin<br />
			**[[6tkj]], [[6tki]], [[6tkh]] - hThr HC + LC + tsetse Thr inhibitor<br />
	**[[5e8e]] - hThr HC + LC + antibody<br />		**[[5e8e]] - hThr HC + LC + antibody<br />
	**[[2a1d]], [[1nu7]] – bThr HC + LC + staphylocoagulase<br />		**[[2a1d]], [[1nu7]] – bThr HC + LC + staphylocoagulase<br />
Line 87:		Line 88:
	*'''Prothrombin'''		*'''Prothrombin'''

	**[[3e6p]], [[2afq]], [[3u69]] - hPThr HC + LC<br />		**[[3e6p]], [[2afq]], [[3u69]], [[6v5t]] - hPThr HC + LC<br />
	**[[3s7h]], [[3s7k]]– hPThr HC + LC (mutant) <br />		**[[3s7h]], [[3s7k]], [[6p9u]] – hPThr HC + LC (mutant) <br />
	**[[3bei]], [[2pgb]], [[2gp9]], [[1tq0]], [[1rd3]], [[4hzh]], [[4h6t]], [[4h6s]] - hPThr HC (mutant) + LC<br />		**[[3bei]], [[2pgb]], [[2gp9]], [[1tq0]], [[1rd3]], [[4hzh]], [[4h6t]], [[4h6s]], [[6bjr]], [[6c2w]] - hPThr HC (mutant) + LC<br />
	**[[1mh0]], [[4nzq]], [[4o03]] - hPThr HC (mutant) <br />		**[[1mh0]], [[4nzq]], [[4o03]] - hPThr HC (mutant) <br />
	**[[1nl1]], [[1nl2]], [[2spt]], [[2pf1]], [[2pf2]] – bPThr residues 1-156		**[[1nl1]], [[1nl2]], [[2spt]], [[2pf1]], [[2pf2]] – bPThr residues 1-156
Line 95:		Line 96:
	*Prothrombin complexes		*Prothrombin complexes

			**[[6cym]] - hPThr HC + LC + inhibitor<br />
	**[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />		**[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />
	**[[3lu9]], [[3bef]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />		**[[3lu9]], [[3bef]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
Line 103:		Line 105:
	**[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br />		**[[4hfp]] - hPThr HC (mutant) + LC + inhibitor<br />
	**[[2pgq]], [[1tq7]] - hPThr HC (mutant) + LC + PPACK<BR />		**[[2pgq]], [[1tq7]] - hPThr HC (mutant) + LC + PPACK<BR />
	**[[2cn0]], [[1t4u]], [[1t4v]], [[1sb1]], [[1k21]], [[1k22]], [[1g30]], [[1g32]], [[1o5g]], [[3tu7]], [[4lxb]], [[5lce]] - hPThr HC + LC + hirudin peptide + inhibitor<br />		**[[6gwe]], [[6t7h]] - hPThr HC + LC + macrocycle<br />
			**[[2cn0]], [[1t4u]], [[1t4v]], [[1sb1]], [[1k21]], [[1k22]], [[1g30]], [[1g32]], [[1o5g]], [[3tu7]], [[4lxb]], [[5lce]], [[6tdt]], [[6eo9]], [[6eo8]], [[6zun]], [[6zuh]], [[6zug]], [[6zv7]], [[6zuu]], [[6zux]], [[6zuw]], [[6zv8]], [[6i51]], [[6t3q]], [[6t4a]], [[6hsx]], [[6t3m]], [[6t52]], [[6t57]], [[6t89]], [[6t8a]], [[6fjt]], [[6t54]], [[6t53]] - hPThr HC + LC + hirudin peptide + inhibitor<br />
	**[[4ax9]] - hPThr HC + LC + hirudin peptide<br />		**[[4ax9]] - hPThr HC + LC + hirudin peptide<br />
	**[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />		**[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />
	**[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />		**[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />
	**[[4i7y]], [[5ew2]], [[5ew1]], [[5cmx]] - hPThr HC + LC + DNA<br />		**[[4i7y]], [[5ew2]], [[5ew1]], [[5cmx]], [[6eo7]], [[6eo6]], [[6gn7]], [[6evv]] - hPThr HC + LC + DNA<br />
	**[[5do4]] - hPThr HC + LC + RNA<br />		**[[5do4]] - hPThr HC + LC + RNA<br />

Line 119:		Line 122:
	**[[5nhu]] - hPThr HC + LC + CE5 anticoagulant<br />		**[[5nhu]] - hPThr HC + LC + CE5 anticoagulant<br />
	**[[5l6n]] - hPThr HC + LC + madanin<br />		**[[5l6n]] - hPThr HC + LC + madanin<br />
			**[[6tkg]], [[6tkl]] - hPThr HC + LC + tsetse Thr inhibitor<br />

	*'''Prethrombin-1'''		*'''Prethrombin-1'''

Michal Harel at 10:20, 29 November 2020

2020-11-29T10:20:03Z

← Older revision		Revision as of 10:20, 29 November 2020
Line 1:		Line 1:
	== 3D Structures of thrombin==		== 3D Structures of thrombin==

	Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}		Updated on {{REVISIONDAY2}}-{{MONTHNAME\|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Thrombin]]
	{{#tree:id=OrganizedByTopic\|openlevels=0\|		{{#tree:id=OrganizedByTopic\|openlevels=0\|

Michal Harel at 10:16, 23 February 2020

2020-02-23T10:16:48Z

← Older revision		Revision as of 10:16, 23 February 2020
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	**[[3r3g]], [[3gic]] - hThr HC + LC - human<br />		**[[3r3g]], [[3gic]] - hThr HC + LC - human<br />
	**[[3jz1]], [[3jz2]], [[2od3]] - hThr HC + LC (mutant) <br />		**[[3jz1]], [[3jz2]], [[2od3]] - hThr HC + LC (mutant) <br />
	**[[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj], [[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />		**[[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj]], [[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />
	**[[2hnt]]– hThr-γ HC + LC<br />		**[[2hnt]]– hThr-γ HC + LC<br />
	**[[3pmb]] - bThr HC + LC – bovine<br />		**[[3pmb]] - bThr HC + LC – bovine<br />

Michal Harel: New page: == 3D Structures of thrombin== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *'''Thrombin''' **3r3g, [[3gic]...

2020-02-23T10:16:27Z

New page: == 3D Structures of thrombin== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *'''Thrombin''' **3r3g, [[3gic]...

New page

== 3D Structures of thrombin==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|

*'''Thrombin'''

**[[3r3g]], [[3gic]] - hThr HC + LC - human 
**[[3jz1]], [[3jz2]], [[2od3]] - hThr HC + LC (mutant) 
**[[3qgn]], [[4rkj]], [[5jdu]], [[6pxq]], [[6pxj], [[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC 
**[[2hnt]]– hThr-γ HC + LC 
**[[3pmb]] - bThr HC + LC – bovine 
**[[2ocv]] - mThr HC + LC - mouse 
**[[3edx]], [[3hk3]], [[3hk6]] - mThr HC (mutant) + LC 

*Thrombin complexes with small molecule

**[[1bhx]], [[1abj]], [[1ppb]] - hThr HC + LC + inhibitor 
**[[4rn6]] - hThr HC (mutant) + inhibitor 
**[[3dd2]] - hThr HC + LC + RNA 
**[[1hao]], [[1hap]], [[1hut]] - hThr HC + LC + DNA 
**[[3bf6]] - hThr HC + LC + suramin 
**[[1xmn]] - hThr HC + LC + heparin 
**[[2h9t]] - hThr HC + LC + suramin + PPACK 
**[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK 
**[[1sfq]], [[1shh]], [[2thf]], [[1thp]], [[1b7x]], [[4rko]] - hThr HC (mutant) + LC + PPACK 
**[[1ook]] - hThr HC + LC + PPACK 
**[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK 
**[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate 
**[[1uvs]], [[1uvt]], [[1uvu]] - bThr HC + LC + inhibitor 
**[[1etr]], [[1ets]], [[1ett]] – bThr-ε HC + LC + inhibitor 

*Thrombin complexes with peptide

**[[5gim]] - hPThr HC + LC + peptide 
**[[3hkj]] - hThr HC (mutant) + LC + proteinase-activated receptor 1 peptide 
**[[1fph]] - hThr HC + LC + fibrinogen peptide 
**[[3bv9]] - hThr HC (mutant) + LC + peptide inhibitor 
**[[2a2x]], [[1eb1]], [[1h8i]], [[1h8d]], [[1dit]], [[1hbt]], [[3u8t]] - hThr HC + LC + peptide inhibitor 
**[[1g37]], [[1eoj]], [[1eol]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor 
**[[1hlt]] - hThr HC + LC + thrombomodulin peptide 
**[[4ch2]], [[4ch8]] - hThr HC + LC + platelet glycoprotein IB α chain peptide 
**[[2ank]], [[3po1]] - hThr HC + LC + peptide + inhibitor 
**[[1dlk]] - bThr HC + LC + peptide inhibitor 
**[[1ycp]], [[1bbr]] – bThr-ε HC + LC + fibrinogen peptide 
**[[1ucy]] - bThr HC + LC + fibrinogen peptide 
**[[3hki]] - mThr HC (mutant) + LC + proteinase-activated receptor 1 peptide 
**[[2pux]] - mThr HC + LC + proteinase-activated receptor 3 peptide 
**[[2pv9]] - mThr HC (mutant) + LC + proteinase-activated receptor 4 peptide 
**[[1dm4]] - mThr HC (mutant) + LC + fibrinogen peptide 

*Thrombin complexes containing hirudin

**[[3c27]], [[2zc9]], [[2zda]], [[2zdv]], [[3egk]], [[2r2m]], [[2v3h]], [[2v3o]], [[2pks]], [[3eq0]], [[3dt0]], [[3dux]], [[3da9]], [[3dhk]], [[2znk]], [[2zo3]], [[3d49]], [[2zhe]], [[2zhf]], [[2zhw]], [[2zg0]], [[2zfq]], [[2zfr]], [[2zhq]], [[2zi2]], [[2ziq]], [[2zff]], [[2zfp]], [[2zgb]], [[2zgx]], [[2zf0]], [[3biu]], [[3biv]], [[2uuj]], [[2uuk]], [[2jh0]], [[2jh5]], [[2jh6]], [[2gde]], [[2bxt]], [[2bxu]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bdy]], [[2feq]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2anm]], [[2w7g]], [[2fes]], [[1ype]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[1vzq]], [[1way]], [[1wbg]], [[1riw]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1oyt]], [[1o2g]], [[1gj4]], [[1gj5]], [[1kts]], [[1ktt]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1c5n]], [[1c5o]], [[1c4y]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1c4u]], [[1c4v]], [[1c1u]], [[1c1v]], [[1c1w]], [[1qj1]], [[1qj6]], [[1qj7]], [[1qhr]], [[1qur]], [[1d4p]], [[1ba8]], [[1bb0]], [[1ca8]], [[1awf]], [[1awh]], [[1bcu]], [[1a61]], [[1a3b]], [[1a3e]], [[1a46]], [[1a5g]], [[1b5g]], [[1tbz]], [[1a4w]], [[1ay6]], [[1ae8]], [[1afe]], [[1ad8]], [[1ai8]], [[1aix]], [[1bmm]], [[1bmn]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1uma]], [[1aht]], [[1fpc]], [[1w7g]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qx5]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]], [[3t5f]], [[3sv2]], [[3si3]], [[3si4]], [[3sha]], [[3shc]], [[3u98]], [[3u9a]], [[3uwj]], [[4e7r]], [[6eo8]], [[6eo9]], [[4loy]] - hThr HC + LC + hirudin peptide + inhibitor 
**[[1zgi]], [[1zgv]], [[1zrb]], [[1z71]], [[1xm1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1nm6]], [[1nt1]], [[1doj]], [[1d9i]], [[1d6w]], [[1qbv]], [[1tmu]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]], [[4baq]], [[4bao]], [[4ban]], [[4bak]], [[4bam]], [[4bah]], [[5lpd]], [[5ahg]], [[5afz]], [[5afy]], [[5af9]], [[5a2m]], [[4yes]], [[4ufg]], [[4uff]], [[4ufe]], [[4ufd]], [[4ueh]], [[4ue7]], [[4udw]], [[4ud9]] - hThr HC + hirudin peptide + inhibitor 
**[[1ny2]], [[8kme]], [[7kme]], [[1a2c]], [[1tom]], [[1hdt]], [[1tmt]], [[1tmb]], [[3u8o]], [[3u8r]] - hThr HC + LC + hirudin peptide + peptide inhibitor 
**[[3hat]] - hThr HC + LC + hirudin peptide + fibrinogen peptide 
**[[2uuf]], [[2pw8]], [[1no9]], [[1c5l]], [[1vr1]], [[4thn]], [[5gds]], [[1hxf]], [[1hxe]], [[1abi]], [[1hgt]], [[1ihs]], [[1iht]], [[1thr]], [[1ths]], [[2hgt]], [[3utu]], [[4ayv]], [[4ayy]], [[4az2]], [[3htc]], [[4htc]] - hThr HC + LC + hirudin peptide 
**[[3vxe]], [[3vxf]] - hThr HC + LC + bivalirudin peptide 
**[[4mlf]] - hThr HC (mutant) + LC + hirudin peptide 
**[[5mm6]], [[5mls]], [[5mjt]] - hThr HC (mutant) + LC + hirudin peptide + inhibitor 
**[[1vit]], [[1hrt]] - bThr HC + LC + hirudin peptide 

*Thrombin complex with protein

**[[2a45]] - hThr HC + LC + fibrinogen α, β, γ chains 
**[[1tb6]] - hThr HC + LC (mutant) + antithrombin 
**[[2b5t]] - hThr HC (mutant) + LC + antithrombin III (mutant) 
**[[4dt7]] - hThr HC (mutant) + LC + vitamin K-dependent protein C peptide 
**[[1jmo]] - hThr HC (mutant) + LC + heparin cofactor II 
**[[4dy7]] - hThr HC (mutant) + LC + glia-derived nexin 
**[[1e0f]] - hThr HC + LC + haemadin 
**[[4boh]] - hThr HC + LC + madanin 
**[[4e05]], [[4e06]] - hThr HC + LC + anophelin 
**[[1dx5]] - hThr HC + LC + thrombomodulin 
**[[3p6z]], [[3p70]] - hThr HC + LC + coagulation factor V 
**[[1de7]] - hThr HC + LC + factor XIII activation peptide 
**[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain 
**[[3b23]] - hThr HC + LC + variegin 
**[[5e8e]] - hThr HC + LC + antibody 
**[[2a1d]], [[1nu7]] – bThr HC + LC + staphylocoagulase 
**[[1avg]] - bThr HC + LC + triabin 
**[[1bth]] - bThr HC (mutant) + LC (mutant) + BPTI 
**[[1toc]] - bThr HC + LC + ornithodorin 
**[[1tbq]], [[1tbr]] - bThr HC + LC + rhodniin 

*'''Prothrombin'''

**[[3e6p]], [[2afq]], [[3u69]] - hPThr HC + LC 
**[[3s7h]], [[3s7k]]– hPThr HC + LC (mutant) 
**[[3bei]], [[2pgb]], [[2gp9]], [[1tq0]], [[1rd3]], [[4hzh]], [[4h6t]], [[4h6s]] - hPThr HC (mutant) + LC 
**[[1mh0]], [[4nzq]], [[4o03]] - hPThr HC (mutant) 
**[[1nl1]], [[1nl2]], [[2spt]], [[2pf1]], [[2pf2]] – bPThr residues 1-156

*Prothrombin complexes

**[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide 
**[[3lu9]], [[3bef]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide 
**[[1sr5]] - hPThr HC + LC + antithrombin III 
**[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314 
**[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide 
**[[1jwt]], [[3c1k]] - hPThr HC + inhibitor 
**[[4hfp]] - hPThr HC (mutant) + LC + inhibitor 
**[[2pgq]], [[1tq7]] - hPThr HC (mutant) + LC + PPACK 
**[[2cn0]], [[1t4u]], [[1t4v]], [[1sb1]], [[1k21]], [[1k22]], [[1g30]], [[1g32]], [[1o5g]], [[3tu7]], [[4lxb]], [[5lce]] - hPThr HC + LC + hirudin peptide + inhibitor 
**[[4ax9]] - hPThr HC + LC + hirudin peptide 
**[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide 
**[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide 
**[[4i7y]], [[5ew2]], [[5ew1]], [[5cmx]] - hPThr HC + LC + DNA 
**[[5do4]] - hPThr HC + LC + RNA 

*Prothrombin complex with protein

**[[1id5]] - hPThr HC + LC + ecotin 
**[[1p8v]] - hPThr HC + LC + platelet glycoprotein IB α chain 
**[[3gis]] - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin 
**[[3b9f]] - hPThr HC (mutant) + LC + protein C inhibitor 
**[[2ody]] - hPThr HC + LC + boophilin 
**[[5nhu]] - hPThr HC + LC + CE5 anticoagulant 
**[[5l6n]] - hPThr HC + LC + madanin 

*'''Prethrombin-1'''

**[[3nxp]] - hThr residues 199-622

*'''Prethrombin-2'''

**[[1nu9]] – hThr + staphylocoagulase 
**[[1mkw]], [[1mkx]] – hThr + bThr HC + LC 
**[[1hag]], [[1hah]] – hThr + hirudin peptide 
**[[1hai]] – hThr + inhibitor 
**[[3sqe]], [[3sqh]] - hThr (mutant)

*'''Meizothrombin'''

**[[1a0h]] - bMThr
}}

[[Category:Topic Page]]