Colicin Js: Difference between revisions
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New page: Colicin Js is a type of Colicin, a bacteriocin made by "E. Coli" which acts against other nearby "E. Coli" to kill them with its cytotoxic domain; its method of killing is as yet unide... |
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Colicin Js is a type of [[Colicin]], a bacteriocin made by | Colicin Js is a type of [[Colicin]], a bacteriocin made by ''E. coli'' which acts against other nearby ''E. coli'' to kill them with its cytotoxic domain; its method of killing is as yet unidentified. | ||
==Synthesis and release== | ==Synthesis and release== | ||
The operon for colicin B is encoded on a plasmid in the cytoplasm of the ''E. coli''. This operon also encodes its [[Colicin Immunity Protein]], [[Cji]], to protect the cell from the cytotoxic activities of the colicin, alongside a protein to aid the release of the colicin outside the cell. | |||
==Mechanism of uptake== | ==Mechanism of uptake== | ||
== | The receptor binding domain of the colicin binds to the outer membrane receptor CjrBC<ref> PMID: 12423780 </ref> on the target cell; it is a constitutively expressed protein parasitised by the colicin. The translocation domain then recruits proteins from the [[Ton]] system to translocate the protein across the membrane and into the cytoplasm. | ||
==References== | |||
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