Structural genomics: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) No edit summary |
Eric Martz (talk | contribs) No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 3: | Line 3: | ||
Structural genomics is a large, international project, started around 2001, that aims to determine new protein structures using high throughput techniques, and to develop faster techniques for [[X-ray crystallography]] and [[NMR]]. | Structural genomics is a large, international project, started around 2001, that aims to determine new protein structures using high throughput techniques, and to develop faster techniques for [[X-ray crystallography]] and [[NMR]]. | ||
Protein sequences are often selected for structure determination because they represent a sequence-family for which no member's structure is known. These are called ''target sequences''. Determination of the structure of such a sequence enables the structures of other sequence-related proteins to be predicted by [[homology modeling]]. Many of the institutions participating in structural genomics report their target sequences, and their progress in determining their structures, in | Protein sequences are often selected for structure determination because they represent a sequence-family for which no member's structure is known. These are called ''target sequences''. Determination of the structure of such a sequence enables the structures of other sequence-related proteins to be predicted by [[homology modeling]]. Many of the institutions participating in structural genomics report their target sequences, and their progress in determining their structures, in [http://sbkb.org/tt/ TargetTrack, the Structural Biology Target Registration Database]. | ||
==Fold Space== | ==Fold Space== | ||
| Line 13: | Line 13: | ||
==See Also== | ==See Also== | ||
*[[Structural Genomics Consortium]] | *[[Structural Genomics Consortium]] | ||
* [http://www.nigms.nih.gov/Research/FeaturedPrograms/PSI/ Protein Structure Initiative (PSI)] | |||
* [http://en.wikipedia.org/wiki/Structural_genomics Structural Genomics] at Wikipedia. | * [http://en.wikipedia.org/wiki/Structural_genomics Structural Genomics] at Wikipedia. | ||
* The impact of extremophiles on structural genomics (and vice versa)<ref>PMID: 17563834</ref>. | * The impact of extremophiles on structural genomics (and vice versa)<ref>PMID: 17563834</ref>. | ||
