Lambda repressor: Difference between revisions
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<StructureSection load=3bdn size=' | <StructureSection load=3bdn size='350' side='right' scene='Bacteriophage_Lambda_Repressor_cI/Homodimer_bound_to_dna/3' caption='Lambda repressor cI protein dimer complex with DNA (PDB code [[3bdn]])'> | ||
== Introduction == | == Introduction == | ||
'''cI''' is a transcription inhibitor of bacteriophage Lambda. Also known as '''Lambda Repressor''', cI is responsible for maintaining the lysogenic life cycle of phage Lambda. This is achieved when two repressor dimers bind cooperatively to adjacent operator sites on the DNA. The cooperative binding induces repression of the ''cro'' gene and simultaneous activation of the ''cI'' gene, which code for proteins Cro and cI, respectively (Stayrook et. al, 2008). | '''cI''' is a transcription inhibitor of bacteriophage Lambda. Also known as '''Lambda Repressor''', cI is responsible for maintaining the lysogenic life cycle of phage Lambda. This is achieved when two repressor dimers bind cooperatively to adjacent operator sites on the DNA. The cooperative binding induces repression of the ''cro'' gene and simultaneous activation of the ''cI'' gene, which code for proteins '''Cro''' and '''cI''', respectively (Stayrook et. al, 2008). | ||
==Structural Overview== | ==Structural Overview== | ||
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== 3D Structures of lambda repressor == | == 3D Structures of lambda repressor == | ||
See [[Bacteriophage repressor]] | |||
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==References== | ==References== | ||
