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| {{STRUCTURE_2axi| PDB=2axi | SIZE=400| SCENE= |right|CAPTION=Human MDM2 (grey) complex with β-hairpin peptide (green), sulfate and morpholino-propane sulfonic acid [[1ycq]] }}
| | <StructureSection load='2axi' size='350' side='right' scene='' caption='Human MDM2 (grey) complex with β-hairpin peptide (green), sulfate and morpholino-propane sulfonic acid [[1ycq]]'> |
| | __TOC__ |
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| ==Function== | | ==Function== |
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| ==3D structures of MDM2== | | ==3D structures of MDM2== |
| | [[MDM2 3D structures]] |
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| | </StructureSection> |
| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *'''MDM2'''
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| **[[4ipf]], [[4j74]] – fMDM2 p53-binding domain (mutant) - frog<br />
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| **[[1z1m]] – hMDM2 N terminal – human - NMR<br />
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| **[[2c6a]], [[2c6b]], [[2cr8]] – hMDM2 C4 Zinc-finger domain – NMR<br />
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| **[[2hdp]] - hMDM2 C4 ring-finger domain – NMR<br />
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| *MDM2 complex with small molecule
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| **[[1rv1]], [[1t4e]], [[3lbk]], [[4dij]], [[3vzv]], [[3w69]], [[3lkb]], [[4lwt]], [[4lwu]], [[4lwv]], [[4oq3]] – hMDM2 (mutant) p53-binding domain + inhibitor<br />
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| **[[3jzk]], [[3lbl]], [[3tu1]], [[4ere]], [[4erf]], [[3tj2]], [[4hbm]], [[4jv7]], [[4jv9]], [[4jve]], [[4jvr]], [[4jwr]], [[4mdn]], [[4mdq]], [[4oas]], [[4oba]], [[4occ]], [[4ode]], [[4odf]], [[4ogn]], [[4ogt]], [[4ogv]], [[4qo4]], [[4hg7]], [[4wt2]] - hMDM2 p53-binding domain + inhibitor<br />
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| **[[2lzg]] - hMDM2 p53-binding domain + inhibitor – NMR<br />
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| **[[3vbg]] - hMDM2 p53-binding domain + indolyl hydantoin<br />
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| **[[1ttv]] - fMDM2 (mutant) p53-binding domain + inhibitor – NMR
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| **[[4j3e]], [[4j7d]], [[4j7e]], [[4jrg]], [[4jsc]] - fMDM2 p53-binding domain (mutant) + inhibitor<br />
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| *MDM2 complex with peptide
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| **[[1ycq]], [[1ycr]] – fMDM2 + p53 peptide <br />
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| **[[1t4f]], [[4hfz]] - hMDM2 (mutant) p53-binding domain + p53 peptide<br />
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| **[[3v3b]] - hMDM2 p53-binding domain + p53 peptide<br />
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| **[[3jzr]] - hMDM2 p53-binding domain + pDI6W peptide<br />
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| **[[4umn]] - hMDM2 p53-binding domain + M06 peptide<br />
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| **[[3jzs]] - hMDM2 p53-binding domain + pDIQ peptide<br />
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| **[[3tpx]] - hMDM2 p53-binding domain + D-peptide inhibitor<br />
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| **[[2axi]], [[2gv2]], [[3eqs]], [[3g03]], [[3iux]], [[3lnj]], [[3lnz]], [[3iwy]] - hMDM2 p53-binding domain + peptide<br />
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| **[[2m86]] - hMDM2 p53-binding domain + cyclotide - NMR<br />
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| **[[2vje]], [[2vjf]] - hMDM2 ring domain + MDM4 peptide<br />
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| }}
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| ==Additional Resources== | | ==Additional Resources== |
