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[[Image:2pdo.gif|left|200px]]


{{Structure
==Crystal Structure of the Putative Acetyltransferase of GNAT Family from Shigella flexneri==
|PDB= 2pdo |SIZE=350|CAPTION= <scene name='initialview01'>2pdo</scene>, resolution 2.00&Aring;
<StructureSection load='2pdo' size='340' side='right'caption='[[2pdo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[2pdo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri_2a_str._2457t Shigella flexneri 2a str. 2457t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PDO FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|GENE= ypeA, SF2487, S_2635 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=42897 Shigella flexneri 2a])
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK03624 PRK03624]</span>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ypeA, SF2487, S_2635 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198215 Shigella flexneri 2a str. 2457T])</td></tr>
|RELATEDENTRY=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pdo OCA], [https://pdbe.org/2pdo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pdo RCSB], [https://www.ebi.ac.uk/pdbsum/2pdo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pdo ProSAT], [https://www.topsan.org/Proteins/MCSG/2pdo TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pdo OCA], [http://www.ebi.ac.uk/pdbsum/2pdo PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pdo RCSB]</span>
</table>
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal Structure of the Putative Acetyltransferase of GNAT Family from Shigella flexneri'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pd/2pdo_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
2PDO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri_2a Shigella flexneri 2a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PDO OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Shigella flexneri 2a]]
  </jmolCheckbox>
[[Category: Single protein]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pdo ConSurf].
[[Category: Holzle, D.]]
<div style="clear:both"></div>
[[Category: Joachimiak, A.]]
__TOC__
[[Category: Kim, Y.]]
</StructureSection>
[[Category: Li, H.]]
[[Category: Large Structures]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Shigella flexneri 2a str. 2457t]]
[[Category: alpha-beta-alpha sandwich]]
[[Category: Holzle, D]]
[[Category: mcsg]]
[[Category: Joachimiak, A]]
[[Category: midwest center for structural genomic]]
[[Category: Kim, Y]]
[[Category: protein structure initiative]]
[[Category: Li, H]]
[[Category: psi-2]]
[[Category: Structural genomic]]
[[Category: structural genomic]]
[[Category: Alpha-beta-alpha sandwich]]
 
[[Category: Mcsg]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:34:32 2008''
[[Category: PSI, Protein structure initiative]]
[[Category: Transferase]]