2ph5: Difference between revisions

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New page: left|200px<br /><applet load="2ph5" size="350" color="white" frame="true" align="right" spinBox="true" caption="2ph5, resolution 2.50Å" /> '''Crystal structure of...
 
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[[Image:2ph5.gif|left|200px]]<br /><applet load="2ph5" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2ph5, resolution 2.50&Aring;" />
'''Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54'''<br />


==About this Structure==
==Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54==
2PH5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila Legionella pneumophila subsp. pneumophila] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Homospermidine_synthase Homospermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.44 2.5.1.44] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH5 OCA].  
<StructureSection load='2ph5' size='340' side='right'caption='[[2ph5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ph5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legph Legph]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PH5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hss, lpg2495 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272624 LEGPH])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Homospermidine_synthase Homospermidine synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.44 2.5.1.44] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ph5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ph5 OCA], [https://pdbe.org/2ph5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ph5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ph5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ph5 ProSAT], [https://www.topsan.org/Proteins/NESGC/2ph5 TOPSAN]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2ph5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ph5 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homospermidine synthase]]
[[Category: Homospermidine synthase]]
[[Category: Legionella pneumophila subsp. pneumophila]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Legph]]
[[Category: Acton, T.B.]]
[[Category: Acton, T B]]
[[Category: Baran, M.C.]]
[[Category: Baran, M C]]
[[Category: Cunningham, K.]]
[[Category: Cunningham, K]]
[[Category: Fang, Y.]]
[[Category: Fang, Y]]
[[Category: Forouhar, F.]]
[[Category: Forouhar, F]]
[[Category: Hunt, J.F.]]
[[Category: Hunt, J F]]
[[Category: Hussain, M.]]
[[Category: Hussain, M]]
[[Category: Janjua, H.]]
[[Category: Janjua, H]]
[[Category: Liu, J.]]
[[Category: Liu, J]]
[[Category: Ma, L-C.]]
[[Category: Ma, L C]]
[[Category: Montelione, G.T.]]
[[Category: Montelione, G T]]
[[Category: NESG, Northeast.Structural.Genomics.Consortium.]]
[[Category: Structural genomic]]
[[Category: Owens, L.]]
[[Category: Owens, L]]
[[Category: Seetharaman, J.]]
[[Category: Seetharaman, J]]
[[Category: Tong, L.]]
[[Category: Tong, L]]
[[Category: Xiao, R.]]
[[Category: Xiao, R]]
[[Category: NAD]]
[[Category: Alpha-beta protein]]
[[Category: SO4]]
[[Category: Nesg]]
[[Category: alpha-beta protein]]
[[Category: PSI, Protein structure initiative]]
[[Category: nesg]]
[[Category: Transferase]]
[[Category: northeast structural genomics consortium]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 15:17:29 2008''

Latest revision as of 15:24, 17 June 2021

Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54

2ph5, resolution 2.50Å

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