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==Crystal structure of lincosamide antibiotic adenylyltransferase LnuA, apo==
==Crystal structure of lincosamide antibiotic adenylyltransferase LnuA, apo==
<StructureSection load='4fo1' size='340' side='right' caption='[[4fo1]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='4fo1' size='340' side='right'caption='[[4fo1]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
[[4fo1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29970 Atcc 29970]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4e8i 4e8i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FO1 OCA]. <br>
<table><tr><td colspan='2'>[[4fo1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4e8i 4e8i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FO1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FO1 FirstGlance]. <br>
<b>[[Ligand|Ligands:]]</b> <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<b>[[Non-Standard_Residue|NonStd Res:]]</b> <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene><br>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fo1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fo1 OCA], [https://pdbe.org/4fo1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fo1 RCSB], [https://www.ebi.ac.uk/pdbsum/4fo1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fo1 ProSAT]</span></td></tr>
<b>[[Related_structure|Related:]]</b> [[4e8j|4e8j]]<br>
</table>
<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
== Function ==
<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fo1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fo1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fo1 RCSB], [http://www.ebi.ac.uk/pdbsum/4fo1 PDBsum]</span><br>
[https://www.uniprot.org/uniprot/LINA_STAHA LINA_STAHA]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 29970]]
[[Category: Large Structures]]
[[Category: Anderson, W F.]]
[[Category: Staphylococcus haemolyticus]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Anderson WF]]
[[Category: Courvalin, P.]]
[[Category: Courvalin P]]
[[Category: Egorova, O.]]
[[Category: Egorova O]]
[[Category: Evdokimova, E.]]
[[Category: Evdokimova E]]
[[Category: Kudritska, M]]
[[Category: Kudritska M]]
[[Category: Minasov, G.]]
[[Category: Minasov G]]
[[Category: Savchenko, A.]]
[[Category: Savchenko A]]
[[Category: Stogios, P J.]]
[[Category: Stogios PJ]]
[[Category: Wawrzak, Z.]]
[[Category: Wawrzak Z]]
[[Category: Yim, V.]]
[[Category: Yim V]]
[[Category: Adenosine triphosphate]]
[[Category: Alpha+beta structure]]
[[Category: Aminoglycoside-2''-adenylyltransferase superfamily]]
[[Category: Antibiotic resistance]]
[[Category: Clindamycin]]
[[Category: Intracellular]]
[[Category: Lincomycin]]
[[Category: Lincosamide adenylyltransferase]]
[[Category: Lincosamide antibiotic]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Nucleotidyltransferase superfamily]]
[[Category: Structural genomic]]
[[Category: Transferase]]

Latest revision as of 20:02, 19 October 2022

Crystal structure of lincosamide antibiotic adenylyltransferase LnuA, apo

4fo1, resolution 2.15Å

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