Fibrin: Difference between revisions

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<StructureSection load='1n73' size='350' side='right' scene='Fibrin/Cv/2' caption='Fibrin α1 subunit (red, yellow), β subunit (Green, blue), γ subunit (orange, magenta) from Petromyzon marinus (PDB entry [[1n73]]'>
<StructureSection load='1n73' size='350' side='right' scene='41/417472/Cv/3' caption='Fibrin α1 subunit (red, yellow), β subunit (cyan, blue), γ subunit (orange, magenta) from Petromyzon marinus (PDB entry [[1n73]])'>


== Function ==
== Function ==
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Overexpression of FIa can cause thrombosis.
Overexpression of FIa can cause thrombosis.
== Structural highlights ==
<scene name='41/417472/Cv/6'>Ca coordination site in β subunit</scene>.
<scene name='41/417472/Cv/7'>Ca coordination site in γ subunit</scene> (PDB entry [[1n73]]).
</StructureSection>
</StructureSection>
== 3D Structures of Fibrin ==
== 3D Structures of Fibrin ==
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[[2hlo]], [[1n86]] - hFIa α, β, γ chains + peptide<br />
[[2hlo]], [[1n86]] - hFIa α, β, γ chains + peptide<br />
[[1n8e]] - hFIa α, β, γ chains <br />
[[1n8e]] - hFIa α, β, γ chains <br />
[[2a45]] - hFIa α, β, γ chains + thrombin<br />
[[1fzc]] – hDDFIa+peptide<br />
[[1n73]] - FIa α, β, γ chains + peptide – Sea lamprey<br />
[[1n73]] - FIa α, β, γ chains + peptide – Sea lamprey<br />
[[1fzc]] – hDDFIa+peptide<br />


== References ==
== References ==