2n5r: Difference between revisions

<StructureSection load='2n5r' size='340' side='right'caption='[[2n5r]]' scene=''>

<table><tr><td colspan='2'>[[2n5r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N5R FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n5r OCA], [https://pdbe.org/2n5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n5r RCSB], [https://www.ebi.ac.uk/pdbsum/2n5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n5r ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/CFLAR_HUMAN CFLAR_HUMAN] Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.<ref>PMID:9880531</ref>  

[[Category: Panaitiu AE]]