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==Crystal Structure of BAZ2B bromodomain in complex with acetylindole compound UZH47==
==Crystal Structure of BAZ2B bromodomain in complex with acetylindole compound UZH47==
<StructureSection load='5e73' size='340' side='right' caption='[[5e73]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
<StructureSection load='5e73' size='340' side='right'caption='[[5e73]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5e73]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E73 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5e73]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E73 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E73 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UO1:N-(1-ACETYL-1H-INDOL-3-YL)-N-(5-HYDROXY-2-METHYLPHENYL)ACETAMIDE'>UO1</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e73 OCA], [http://pdbe.org/5e73 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e73 RCSB], [http://www.ebi.ac.uk/pdbsum/5e73 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e73 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UO1:N-(1-ACETYL-1H-INDOL-3-YL)-N-(5-HYDROXY-2-METHYLPHENYL)ACETAMIDE'>UO1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e73 OCA], [https://pdbe.org/5e73 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e73 RCSB], [https://www.ebi.ac.uk/pdbsum/5e73 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e73 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.  
[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5e73" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5e73" style="background-color:#fffaf0;"></div>
==See Also==
*[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Caflisch, A]]
[[Category: Homo sapiens]]
[[Category: Lolli, G]]
[[Category: Large Structures]]
[[Category: Nevado, C]]
[[Category: Caflisch A]]
[[Category: Spiliotopoulos, D]]
[[Category: Lolli G]]
[[Category: Unzue, A]]
[[Category: Nevado C]]
[[Category: Four helical bundle]]
[[Category: Spiliotopoulos D]]
[[Category: Transcription]]
[[Category: Unzue A]]

Latest revision as of 06:15, 5 July 2023

Crystal Structure of BAZ2B bromodomain in complex with acetylindole compound UZH47

5e73, resolution 1.71Å

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