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==Structural insights of isocitrate lyases from Magnaporthe oryzae==
==Structural insights of isocitrate lyases from Magnaporthe oryzae==
<StructureSection load='5e9f' size='340' side='right' caption='[[5e9f]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5e9f' size='340' side='right'caption='[[5e9f]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5e9f]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E9F FirstGlance]. <br>
<table><tr><td colspan='2'>[[5e9f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyricularia_oryzae_70-15 Pyricularia oryzae 70-15]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E9F FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5e9g|5e9g]], [[5e9h|5e9h]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e9f OCA], [http://pdbe.org/5e9f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e9f RCSB], [http://www.ebi.ac.uk/pdbsum/5e9f PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e9f OCA], [https://pdbe.org/5e9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e9f RCSB], [https://www.ebi.ac.uk/pdbsum/5e9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e9f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACEA_MAGO7 ACEA_MAGO7]] Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2-methylisocitrate (By similarity). plays an important role in plant pathogenicity.[UniProtKB:P28240]<ref>PMID:12622815</ref>
[https://www.uniprot.org/uniprot/ACEA_MAGO7 ACEA_MAGO7] Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2-methylisocitrate (By similarity). plays an important role in plant pathogenicity.[UniProtKB:P28240]<ref>PMID:12622815</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cho, Y]]
[[Category: Large Structures]]
[[Category: Lee, Y H]]
[[Category: Pyricularia oryzae 70-15]]
[[Category: Lee, Y W]]
[[Category: Cho Y]]
[[Category: Park, Y]]
[[Category: Lee Y-H]]
[[Category: Rhee, S]]
[[Category: Lee Y-W]]
[[Category: Lyase]]
[[Category: Park Y]]
[[Category: Lyase activity]]
[[Category: Rhee S]]
[[Category: Tim beta/alpha-barrel]]