5fve: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:


==Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide==
==Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide==
<StructureSection load='5fve' size='340' side='right' caption='[[5fve]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
<StructureSection load='5fve' size='340' side='right'caption='[[5fve]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fve]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FVE FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fve]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FVE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2HO:3,4-DIFLUOROBENZAMIDE'>2HO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2HO:3,4-DIFLUOROBENZAMIDE'>2HO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fve OCA], [http://pdbe.org/5fve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fve RCSB], [http://www.ebi.ac.uk/pdbsum/5fve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fve ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fve OCA], [https://pdbe.org/5fve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fve RCSB], [https://www.ebi.ac.uk/pdbsum/5fve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fve ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPO3B_HELPY DPO3B_HELPY]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity).  
[https://www.uniprot.org/uniprot/DPO3B_HELPY DPO3B_HELPY] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 21:


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Campylobacter pylori]]
[[Category: Helicobacter pylori 26695]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Gourinath, S]]
[[Category: Gourinath S]]
[[Category: Pandey, P]]
[[Category: Pandey P]]
[[Category: Dna clamp]]
[[Category: Sliding clamp]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/5fve"