1f2k: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 3: | Line 3: | ||
<StructureSection load='1f2k' size='340' side='right'caption='[[1f2k]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='1f2k' size='340' side='right'caption='[[1f2k]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1f2k]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F2K OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[1f2k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_castellanii Acanthamoeba castellanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F2K FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f2k OCA], [https://pdbe.org/1f2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f2k RCSB], [https://www.ebi.ac.uk/pdbsum/1f2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f2k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PROF2_ACACA PROF2_ACACA] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 21: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[Profilin|Profilin]] | *[[Profilin 3D Structures|Profilin 3D Structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Acanthamoeba castellanii]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Almo | [[Category: Almo SC]] | ||
[[Category: Fedorov | [[Category: Fedorov AA]] | ||
[[Category: Kaiser | [[Category: Kaiser DA]] | ||
[[Category: Mahoney | [[Category: Mahoney N]] | ||
[[Category: Shi | [[Category: Shi W]] | ||
Latest revision as of 06:01, 9 August 2023
CRYSTAL STRUCTURE OF ACANTHAMOEBA CASTELLANII PROFILIN II, CUBIC CRYSTAL FORM
| ||||||||||||
