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[[Image:1ick.jpg|left|200px]]
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{{STRUCTURE_1ick|  PDB=1ick  |  SCENE=  }}
'''LEFT-HANDED Z-DNA HEXAMER DUPLEX D(CGCGCG)2'''


==LEFT-HANDED Z-DNA HEXAMER DUPLEX D(CGCGCG)2==
<StructureSection load='1ick' size='340' side='right'caption='[[1ick]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1ick]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ICK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ICK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ick FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ick OCA], [https://pdbe.org/1ick PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ick RCSB], [https://www.ebi.ac.uk/pdbsum/1ick PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ick ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The crystal structure of a left-handed Z-DNA hexamer duplex d(CGCGCG)(2) has been solved based on the anomalous diffraction signal of inherent P atoms using data collected at the single wavelength of 1.54 A. The anomalous signal of about 2% of the total diffracted intensity, constant for all nucleic acids, may be generally useful for solving crystal structures of DNA and RNA oligomers. The multiplicity of intensity measurements is shown to crucially affect the data quality and the ability to solve the phase problem. The anisotropic model refined to an R factor of 8.9% at 0.95 A resolution.


==Overview==
Anomalous signal of phosphorus used for phasing DNA oligomer: importance of data redundancy.,Dauter Z, Adamiak DA Acta Crystallogr D Biol Crystallogr. 2001 Jul;57(Pt 7):990-5. Epub 2001, Jun 21. PMID:11418767<ref>PMID:11418767</ref>
The crystal structure of a left-handed Z-DNA hexamer duplex d(CGCGCG)(2) has been solved based on the anomalous diffraction signal of inherent P atoms using data collected at the single wavelength of 1.54 A. The anomalous signal of about 2% of the total diffracted intensity, constant for all nucleic acids, may be generally useful for solving crystal structures of DNA and RNA oligomers. The multiplicity of intensity measurements is shown to crucially affect the data quality and the ability to solve the phase problem. The anisotropic model refined to an R factor of 8.9% at 0.95 A resolution.


==About this Structure==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ICK OCA].
</div>
<div class="pdbe-citations 1ick" style="background-color:#fffaf0;"></div>


==Reference==
==See Also==
Anomalous signal of phosphorus used for phasing DNA oligomer: importance of data redundancy., Dauter Z, Adamiak DA, Acta Crystallogr D Biol Crystallogr. 2001 Jul;57(Pt 7):990-5. Epub 2001, Jun 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11418767 11418767]
*[[Z-DNA|Z-DNA]]
[[Category: Adamiak, D A.]]
== References ==
[[Category: Dauter, Z.]]
<references/>
[[Category: Left-handed z-dna oligomer]]
__TOC__
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 19:50:44 2008''
</StructureSection>
[[Category: Large Structures]]
[[Category: Adamiak DA]]
[[Category: Dauter Z]]
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