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==Structure of 23S rRNA of the large ribosomal subunit from Deinococcus radiodurans in complex with the macrolide josamycin==
==Structure of 23S rRNA of the large ribosomal subunit from Deinococcus radiodurans in complex with the macrolide josamycin==
<StructureSection load='2o44' size='340' side='right' caption='[[2o44]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='2o44' size='340' side='right'caption='[[2o44]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2o44]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O44 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2o44]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O44 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JOS:(2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10S,12E,14Z,16R)-4-(ACETYLOXY)-10-HYDROXY-5-METHOXY-9,16-DIMETHYL-2-OXO-7-(2-OXOETHYL)OXACYCLOHEXADECA-12,14-DIEN-6-YL]OXY}-4-(DIMETHYLAMINO)-5-HYDROXY-2-METHYLTETRAHYDRO-2H-PYRAN-3-YL]OXY}-4-HYDROXY-2,4-DIMETHYLTETRAHYDRO-2H-PYRAN-3-YL+3-METHYLBUTANOATE'>JOS</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2o43|2o43]], [[2o45|2o45]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JOS:(2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10S,12E,14Z,16R)-4-(ACETYLOXY)-10-HYDROXY-5-METHOXY-9,16-DIMETHYL-2-OXO-7-(2-OXOETHYL)OXACYCLOHEXADECA-12,14-DIEN-6-YL]OXY}-4-(DIMETHYLAMINO)-5-HYDROXY-2-METHYLTETRAHYDRO-2H-PYRAN-3-YL]OXY}-4-HYDROXY-2,4-DIMETHYLTETRAHYDRO-2H-PYRAN-3-YL+3-METHYLBUTANOATE'>JOS</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o44 RCSB], [http://www.ebi.ac.uk/pdbsum/2o44 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o44 OCA], [https://pdbe.org/2o44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o44 RCSB], [https://www.ebi.ac.uk/pdbsum/2o44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o44 ProSAT]</span></td></tr>
<table>
</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Deinococcus radiodurans]]
[[Category: Deinococcus radiodurans]]
[[Category: Auerbach-Nevo, T.]]
[[Category: Large Structures]]
[[Category: Daram, D.]]
[[Category: Auerbach-Nevo T]]
[[Category: Pyetan, E.]]
[[Category: Daram D]]
[[Category: Yonath, A.]]
[[Category: Pyetan E]]
[[Category: Macrolide]]
[[Category: Yonath A]]
[[Category: Ribosome]]
[[Category: Rna]]

Latest revision as of 10:30, 30 August 2023

Structure of 23S rRNA of the large ribosomal subunit from Deinococcus radiodurans in complex with the macrolide josamycin

2o44, resolution 3.30Å

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