2oym: Difference between revisions

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[[Image:2oym.jpg|left|200px]]


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==Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex==
The line below this paragraph, containing "STRUCTURE_2oym", creates the "Structure Box" on the page.
<StructureSection load='2oym' size='340' side='right'caption='[[2oym]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2oym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OYM FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MNI:N-{[(2R,3R,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PYRROLIDIN-2-YL]METHYL}-4-(DIMETHYLAMINO)BENZAMIDE'>MNI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_2oym|  PDB=2oym  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oym OCA], [https://pdbe.org/2oym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oym RCSB], [https://www.ebi.ac.uk/pdbsum/2oym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oym ProSAT]</span></td></tr>
 
</table>
'''Endo-glycoceramidase II from Rhodococcus sp.: five-membered iminocyclitol complex'''
== Function ==
 
[https://www.uniprot.org/uniprot/O33853_RHOSO O33853_RHOSO]  
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2OYM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OYM OCA].  
Check<jmol>
 
  <jmolCheckbox>
==Reference==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/2oym_consurf.spt"</scriptWhenChecked>
The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system., Caines ME, Hancock SM, Tarling CA, Wrodnigg TM, Stick RV, Stutz AE, Vasella A, Withers SG, Strynadka NC, Angew Chem Int Ed Engl. 2007;46(24):4474-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17487923 17487923]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Endoglycosylceramidase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Rhodococcus sp.]]
  </jmolCheckbox>
[[Category: Single protein]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oym ConSurf].
[[Category: Caines, M E.C.]]
<div style="clear:both"></div>
[[Category: Strynadka, N C.J.]]
__TOC__
[[Category: Hydrolase]]
</StructureSection>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 11:56:38 2008''
[[Category: Large Structures]]
[[Category: Rhodococcus sp]]
[[Category: Caines MEC]]
[[Category: Strynadka NCJ]]