2p3z: Difference between revisions

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[[Image:2p3z.gif|left|200px]]


{{Structure
==Crystal structure of L-Rhamnonate dehydratase from Salmonella typhimurium==
|PDB= 2p3z |SIZE=350|CAPTION= <scene name='initialview01'>2p3z</scene>, resolution 1.80&Aring;
<StructureSection load='2p3z' size='340' side='right'caption='[[2p3z]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
<table><tr><td colspan='2'>[[2p3z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P3Z FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/L-rhamnonate_dehydratase L-rhamnonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.90 4.2.1.90] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE= yfaW, STM2291 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG4948 COG4948], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03327 MR_like_2]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3z OCA], [https://pdbe.org/2p3z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p3z RCSB], [https://www.ebi.ac.uk/pdbsum/2p3z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3z ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2p3z TOPSAN]</span></td></tr>
|RELATEDENTRY=[[2gsh|2GSH]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3z OCA], [http://www.ebi.ac.uk/pdbsum/2p3z PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p3z RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/RHMD_SALTY RHMD_SALTY] Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.<ref>PMID:18754693</ref>
 
== Evolutionary Conservation ==
'''Crystal structure of L-Rhamnonate dehydratase from Salmonella typhimurium'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/2p3z_consurf.spt"</scriptWhenChecked>
2P3Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3Z OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: L-rhamnonate dehydratase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Salmonella typhimurium]]
  </jmolCheckbox>
[[Category: Single protein]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p3z ConSurf].
[[Category: Adams, J M.]]
<div style="clear:both"></div>
[[Category: Almo, S C.]]
== References ==
[[Category: Burley, S K.]]
<references/>
[[Category: Dickey, M.]]
__TOC__
[[Category: Gerlt, J.]]
</StructureSection>
[[Category: Malashkevich, V N.]]
[[Category: Large Structures]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Sauder, J M.]]
[[Category: Adams JM]]
[[Category: Wasserman, S R.]]
[[Category: Almo SC]]
[[Category: enolase]]
[[Category: Burley SK]]
[[Category: new york structural genomics research consortium]]
[[Category: Dickey M]]
[[Category: new york structural genomix research consortium]]
[[Category: Gerlt J]]
[[Category: nysgrc]]
[[Category: Malashkevich VN]]
[[Category: nysgxrc]]
[[Category: Sauder JM]]
[[Category: protein structure initiative]]
[[Category: Wasserman SR]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:28:49 2008''
Retrieved from "https://proteopedia.org/2p3z"