3b6a: Difference between revisions
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==Crystal structure of the Streptomyces coelicolor TetR family protein ActR in complex with actinorhodin== | ==Crystal structure of the Streptomyces coelicolor TetR family protein ActR in complex with actinorhodin== | ||
<StructureSection load='3b6a' size='340' side='right' caption='[[3b6a]], [[Resolution|resolution]] 3.05Å' scene=''> | <StructureSection load='3b6a' size='340' side='right'caption='[[3b6a]], [[Resolution|resolution]] 3.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3b6a]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3b6a]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B6A FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZCT:2,2-[(1R,1R,3S,3S)-6,6,9,9-TETRAHYDROXY-1,1-DIMETHYL-5,5,10,10-TETRAOXO-3,3,4,4,5,5,10,10-OCTAHYDRO-1H,1H-8,8-BIBENZO[G]ISOCHROMENE-3,3-DIYL]DIACETIC+ACID'>ZCT</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZCT:2,2-[(1R,1R,3S,3S)-6,6,9,9-TETRAHYDROXY-1,1-DIMETHYL-5,5,10,10-TETRAOXO-3,3,4,4,5,5,10,10-OCTAHYDRO-1H,1H-8,8-BIBENZO[G]ISOCHROMENE-3,3-DIYL]DIACETIC+ACID'>ZCT</scene></td></tr> | |||
<tr | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6a OCA], [https://pdbe.org/3b6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b6a RCSB], [https://www.ebi.ac.uk/pdbsum/3b6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b6a ProSAT]</span></td></tr> | ||
</table> | |||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/Q53901_STRCH Q53901_STRCH] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6a_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6a_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b6a ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3b6a" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Streptomyces coelicolor]] | [[Category: Streptomyces coelicolor]] | ||
[[Category: Junop | [[Category: Junop MS]] | ||
[[Category: Willems | [[Category: Willems AR]] | ||
Latest revision as of 12:02, 30 August 2023
Crystal structure of the Streptomyces coelicolor TetR family protein ActR in complex with actinorhodin
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