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==PglD from Campylobacter jejuni, NCTC 11168, with native substrate==
==PglD from Campylobacter jejuni, NCTC 11168, with native substrate==
<StructureSection load='3bss' size='340' side='right' caption='[[3bss]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3bss' size='340' side='right'caption='[[3bss]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3bss]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"campylobacter_fetus_subsp._jejuni"_smibert_1974 "campylobacter fetus subsp. jejuni" smibert 1974]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BSS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3bss]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BSS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UD4:UDP-2-ACETAMIDO-4-AMINO-2,4,6-TRIDEOXY-ALPHA-D-GLUCOPYRANOSE'>UD4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2npo|2npo]], [[3bsw|3bsw]], [[3bsy|3bsy]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UD4:UDP-2-ACETAMIDO-4-AMINO-2,4,6-TRIDEOXY-ALPHA-D-GLUCOPYRANOSE'>UD4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pglD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=197 "Campylobacter fetus subsp. jejuni" Smibert 1974])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bss OCA], [https://pdbe.org/3bss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bss RCSB], [https://www.ebi.ac.uk/pdbsum/3bss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bss ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bss OCA], [http://pdbe.org/3bss PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bss RCSB], [http://www.ebi.ac.uk/pdbsum/3bss PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bss ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PGLD_CAMJE PGLD_CAMJE]] Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N'-diacetylbacillosamine in the N-linked protein glycosylation pathway.<ref>PMID:17087520</ref> <ref>PMID:19448740</ref>
[https://www.uniprot.org/uniprot/PGLD_CAMJE PGLD_CAMJE] Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N'-diacetylbacillosamine in the N-linked protein glycosylation pathway.<ref>PMID:17087520</ref> <ref>PMID:19448740</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/3bss_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/3bss_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Campylobacter fetus subsp. jejuni smibert 1974]]
[[Category: Campylobacter jejuni]]
[[Category: UDP-N-acetylglucosamine diphosphorylase]]
[[Category: Large Structures]]
[[Category: Imperiali, B]]
[[Category: Imperiali B]]
[[Category: Olivier, N B]]
[[Category: Olivier NB]]
[[Category: Acetyl coenzyme z]]
[[Category: Bacillosamine]]
[[Category: Campylobacter]]
[[Category: Hexapeptide repeat]]
[[Category: Left-hand beta helix]]
[[Category: N-linked glycosylation]]
[[Category: Pgl]]
[[Category: Rossmann fold]]
[[Category: Transferase]]
[[Category: Udp]]
Retrieved from "https://proteopedia.org/3bss"