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==Crystal structure of human brain glycogen phosphorylase==
==Crystal structure of human brain glycogen phosphorylase==
<StructureSection load='5iko' size='340' side='right' caption='[[5iko]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='5iko' size='340' side='right'caption='[[5iko]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5iko]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IKO FirstGlance]. <br>
<table><tr><td colspan='2'>[[5iko]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IKO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iko OCA], [http://pdbe.org/5iko PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iko RCSB], [http://www.ebi.ac.uk/pdbsum/5iko PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iko ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iko OCA], [https://pdbe.org/5iko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iko RCSB], [https://www.ebi.ac.uk/pdbsum/5iko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iko ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PYGB_HUMAN PYGB_HUMAN]] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.  
[https://www.uniprot.org/uniprot/PYGB_HUMAN PYGB_HUMAN] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5iko" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5iko" style="background-color:#fffaf0;"></div>
==See Also==
*[[Glycogen phosphorylase 3D structures|Glycogen phosphorylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Phosphorylase]]
[[Category: Homo sapiens]]
[[Category: Haouz, A]]
[[Category: Large Structures]]
[[Category: Mathieu, C]]
[[Category: Haouz A]]
[[Category: Rodrigues-Lima, F]]
[[Category: Li de la Sierra-Gallay I]]
[[Category: Sierra-Gallay, I Li de la]]
[[Category: Mathieu C]]
[[Category: Xu, X]]
[[Category: Rodrigues-Lima F]]
[[Category: Allosteric enzyme]]
[[Category: Xu X]]
[[Category: Glycogen disease]]
[[Category: Glycogen metabolism]]
[[Category: Glycogen phosphorylase]]
[[Category: Glycosyltransferase]]
[[Category: Gp]]
[[Category: Nucleotide-binding]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/5iko"