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[[Image:3gla.png|left|200px]]


{{STRUCTURE_3gla| PDB=3gla | SCENE= }}
==Crystal Structure of the hspA from Xanthomonas axonopodis==
<StructureSection load='3gla' size='340' side='right'caption='[[3gla]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3gla]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_citri Xanthomonas citri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GLA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gla OCA], [https://pdbe.org/3gla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gla RCSB], [https://www.ebi.ac.uk/pdbsum/3gla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gla ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8PNC2_XANAC Q8PNC2_XANAC]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/3gla_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gla ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The hspA gene (XAC1151) from Xanthomonas axonopodis pv. citri encodes a protein of 158 amino acids that belongs to the small heat-shock protein (sHSP) family of proteins. These proteins function as molecular chaperones by preventing protein aggregation. The protein was crystallized using the sitting-drop vapour-diffusion method in the presence of ammonium phosphate. X-ray diffraction data were collected to 1.65 angstroms resolution using a synchrotron-radiation source. The crystal belongs to the rhombohedral space group R3, with unit-cell parameters a = b = 128.7, c = 55.3 angstroms. The crystal structure was solved by molecular-replacement methods. Structure refinement is in progress.


===Crystal Structure of the hspA from Xanthomonas axonopodis===
Crystallization and preliminary X-ray diffraction analysis of XAC1151, a small heat-shock protein from Xanthomonas axonopodis pv. citri belonging to the alpha-crystallin family.,Hilario E, Teixeira EC, Pedroso GA, Bertolini MC, Medrano FJ Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):446-8. Epub 2006 Apr 12. PMID:16682772<ref>PMID:16682772</ref>


{{ABSTRACT_PUBMED_16682772}}
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
</div>
==About this Structure==
<div class="pdbe-citations 3gla" style="background-color:#fffaf0;"></div>
[[3gla]] is a 2 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/Xanthomonas_citri Xanthomonas citri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLA OCA].


==See Also==
==See Also==
*[[Heat Shock Proteins|Heat Shock Proteins]]
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:016682772</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Xanthomonas citri]]
[[Category: Xanthomonas citri]]
[[Category: Bertolini, M C.]]
[[Category: Bertolini MC]]
[[Category: Hilario, E.]]
[[Category: Hilario E]]
[[Category: Medrano, F J.]]
[[Category: Medrano FJ]]
[[Category: Chaperone]]
[[Category: High resolution]]
[[Category: Hspa]]
[[Category: Shp]]
[[Category: Shsp]]
[[Category: Stress response]]
[[Category: Xanthomonas axonopodi]]

Latest revision as of 07:07, 6 September 2023

Crystal Structure of the hspA from Xanthomonas axonopodis

3gla, resolution 1.64Å

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