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==Crystal structure of mutant Y305F expressed in E. coli in the copper amine oxidase from hansenula polymorpha==
==Crystal structure of mutant Y305F expressed in E. coli in the copper amine oxidase from hansenula polymorpha==
<StructureSection load='3nbb' size='340' side='right' caption='[[3nbb]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='3nbb' size='340' side='right'caption='[[3nbb]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3nbb]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NBB FirstGlance]. <br>
<table><tr><td colspan='2'>[[3nbb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NBB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ME0:HYDROXY-L-METHIONINE'>ME0</scene>, <scene name='pdbligand=TY8:2,4-BIS(HYDROPEROXY)-5-HYDROXY-L-PHENYLALANINE'>TY8</scene>, <scene name='pdbligand=TY9:3,4-BIS(HYDROPEROXY)-5-HYDROXY-L-PHENYLALANINE'>TY9</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=ME0:HYDROXY-L-METHIONINE'>ME0</scene>, <scene name='pdbligand=TY8:2,4-BIS(HYDROPEROXY)-5-HYDROXY-L-PHENYLALANINE'>TY8</scene>, <scene name='pdbligand=TY9:3,4-BIS(HYDROPEROXY)-5-HYDROXY-L-PHENYLALANINE'>TY9</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a2v|1a2v]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nbb OCA], [https://pdbe.org/3nbb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nbb RCSB], [https://www.ebi.ac.uk/pdbsum/3nbb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nbb ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Primary-amine_oxidase Primary-amine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 1.4.3.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nbb OCA], [http://pdbe.org/3nbb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nbb RCSB], [http://www.ebi.ac.uk/pdbsum/3nbb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nbb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AMO_PICAN AMO_PICAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nb/3nbb_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nb/3nbb_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Copper Amine Oxidase|Copper Amine Oxidase]]
*[[Copper amine oxidase 3D structures|Copper amine oxidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Primary-amine oxidase]]
[[Category: Large Structures]]
[[Category: Chen, Z]]
[[Category: Ogataea angusta]]
[[Category: Datta, S]]
[[Category: Chen Z]]
[[Category: DuBois, J L]]
[[Category: Datta S]]
[[Category: Klinman, J P]]
[[Category: DuBois JL]]
[[Category: Mathews, F S]]
[[Category: Klinman JP]]
[[Category: Amine oxidase]]
[[Category: Mathews FS]]
[[Category: Oxidoreductase]]
[[Category: Quinoprotein]]

Latest revision as of 09:12, 6 September 2023

Crystal structure of mutant Y305F expressed in E. coli in the copper amine oxidase from hansenula polymorpha

3nbb, resolution 2.05Å

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