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==The structure of aIF2gamma subunit H20F from archaeon Sulfolobus solfataricus complexed with GDPCP==
==The structure of aIF2gamma subunit H20F from archaeon Sulfolobus solfataricus complexed with GDPCP==
<StructureSection load='4nbs' size='340' side='right' caption='[[4nbs]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
<StructureSection load='4nbs' size='340' side='right'caption='[[4nbs]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4nbs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NBS FirstGlance]. <br>
<table><tr><td colspan='2'>[[4nbs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NBS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.305&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nbs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nbs OCA], [http://pdbe.org/4nbs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nbs RCSB], [http://www.ebi.ac.uk/pdbsum/4nbs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nbs ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nbs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nbs OCA], [https://pdbe.org/4nbs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nbs RCSB], [https://www.ebi.ac.uk/pdbsum/4nbs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nbs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).  
[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arhipova, V I]]
[[Category: Large Structures]]
[[Category: Gabdulkhakov, A G]]
[[Category: Saccharolobus solfataricus]]
[[Category: Garber, M B]]
[[Category: Arhipova VI]]
[[Category: Kravchenko, O V]]
[[Category: Gabdulkhakov AG]]
[[Category: Nikonov, O S]]
[[Category: Garber MB]]
[[Category: Nikonov, S V]]
[[Category: Kravchenko OV]]
[[Category: Nikulin, A D]]
[[Category: Nikonov OS]]
[[Category: Stolboushkina, E A]]
[[Category: Nikonov SV]]
[[Category: Gtp-binding]]
[[Category: Nikulin AD]]
[[Category: Rna-binding]]
[[Category: Stolboushkina EA]]
[[Category: Translation]]
[[Category: Translation initiation]]

Latest revision as of 16:52, 20 September 2023

The structure of aIF2gamma subunit H20F from archaeon Sulfolobus solfataricus complexed with GDPCP

4nbs, resolution 2.31Å

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