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==Crystal structure of a multi-drug resistant clinical isolate-769 HIV-1 protease variant that is resistant to the dimerization inhibitory activity of TLF-PafF==
==Crystal structure of a multi-drug resistant clinical isolate-769 HIV-1 protease variant that is resistant to the dimerization inhibitory activity of TLF-PafF==
<StructureSection load='4nkk' size='340' side='right' caption='[[4nkk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4nkk' size='340' side='right'caption='[[4nkk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4nkk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NKK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NKK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4nkk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NKK FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pj6|3pj6]], [[1tw7|1tw7]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nkk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nkk RCSB], [http://www.ebi.ac.uk/pdbsum/4nkk PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nkk OCA], [https://pdbe.org/4nkk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nkk RCSB], [https://www.ebi.ac.uk/pdbsum/4nkk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nkk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q000H7_9HIV1 Q000H7_9HIV1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4nkk" style="background-color:#fffaf0;"></div>
==See Also==
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Kovari, L C]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Proteasa, G]]
[[Category: Large Structures]]
[[Category: Yedidi, R S]]
[[Category: Kovari LC]]
[[Category: Aid]]
[[Category: Proteasa G]]
[[Category: Clinical isolate 769]]
[[Category: Yedidi RS]]
[[Category: Dimer protease]]
[[Category: Dimerization inhibitor]]
[[Category: Hiv]]
[[Category: Hiv-1 protease]]
[[Category: Hydrolase]]
[[Category: Multidrug-resistance]]
[[Category: Protease inhibitor]]
Retrieved from "https://proteopedia.org/4nkk"