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==The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and oxaliplatin==
==The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and oxaliplatin==
<StructureSection load='4s18' size='340' side='right' caption='[[4s18]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
<StructureSection load='4s18' size='340' side='right'caption='[[4s18]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4s18]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S18 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S18 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4s18]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S18 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PT:CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)'>1PT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4s0q|4s0q]], [[4ot4|4ot4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PT:CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)'>1PT</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s18 OCA], [https://pdbe.org/4s18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s18 RCSB], [https://www.ebi.ac.uk/pdbsum/4s18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s18 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s18 OCA], [http://pdbe.org/4s18 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4s18 RCSB], [http://www.ebi.ac.uk/pdbsum/4s18 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4s18" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4s18" style="background-color:#fffaf0;"></div>
==See Also==
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pancreatic ribonuclease]]
[[Category: Bos taurus]]
[[Category: Merlino, A]]
[[Category: Large Structures]]
[[Category: Bovine pancrea]]
[[Category: Merlino A]]
[[Category: Cleavage of rna]]
[[Category: Hydrolase]]
[[Category: Ribonuclease fold]]
[[Category: Rna]]
Retrieved from "https://proteopedia.org/4s18"