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==CRYSTAL STRUCTURE OF CANDIDA ALBICANS PROTEIN FARNESYLTRANSFERASE IN APO FORM==
==CRYSTAL STRUCTURE OF CANDIDA ALBICANS PROTEIN FARNESYLTRANSFERASE IN APO FORM==
<StructureSection load='4ydo' size='340' side='right' caption='[[4ydo]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='4ydo' size='340' side='right'caption='[[4ydo]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ydo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YDO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ydo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans] and [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YDO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yde|4yde]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ydo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydo OCA], [http://pdbe.org/4ydo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ydo RCSB], [http://www.ebi.ac.uk/pdbsum/4ydo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ydo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydo OCA], [https://pdbe.org/4ydo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ydo RCSB], [https://www.ebi.ac.uk/pdbsum/4ydo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ydo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FNTA_CANAX FNTA_CANAX]] Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.  
[https://www.uniprot.org/uniprot/FNTA_CANAX FNTA_CANAX] Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beese, L S]]
[[Category: Candida albicans]]
[[Category: Hast, M A]]
[[Category: Candida albicans SC5314]]
[[Category: Kumar, S]]
[[Category: Large Structures]]
[[Category: Mabanglo, M F]]
[[Category: Beese LS]]
[[Category: Shi, Y]]
[[Category: Hast MA]]
[[Category: Farnesyl transferase]]
[[Category: Kumar S]]
[[Category: Transferase]]
[[Category: Mabanglo MF]]
[[Category: Shi Y]]
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