5ku7: Difference between revisions

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<StructureSection load='5ku7' size='340' side='right'caption='[[5ku7]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5ku7' size='340' side='right'caption='[[5ku7]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ku7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Muscadine_grape Muscadine grape]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KU7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ku7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_rotundifolia Vitis rotundifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KU7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RPV1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=103349 Muscadine grape])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ku7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ku7 OCA], [http://pdbe.org/5ku7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ku7 RCSB], [http://www.ebi.ac.uk/pdbsum/5ku7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ku7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ku7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ku7 OCA], [https://pdbe.org/5ku7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ku7 RCSB], [https://www.ebi.ac.uk/pdbsum/5ku7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ku7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPV1_VITRO RPV1_VITRO] Disease resistance (R) protein that confers resistance to multiple powdery and downy mildew by promoting cell death (PubMed:24033846, PubMed:28008335). Acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792).<ref>PMID:24033846</ref> <ref>PMID:28008335</ref> <ref>PMID:31439792</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Muscadine grape]]
[[Category: Vitis rotundifolia]]
[[Category: Ericsson, D J]]
[[Category: Ericsson DJ]]
[[Category: Kobe, B]]
[[Category: Kobe B]]
[[Category: Williams, S J]]
[[Category: Williams SJ]]
[[Category: Plant nlr]]
[[Category: Signaling protein]]
[[Category: Tir domain]]