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==Naegleria fowleri CYP51-voriconazole complex==
==Naegleria fowleri CYP51-voriconazole complex==
<StructureSection load='6ay6' size='340' side='right' caption='[[6ay6]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='6ay6' size='340' side='right'caption='[[6ay6]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ay6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Brain_eating_amoeba Brain eating amoeba]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AY6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ay6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naegleria_fowleri Naegleria fowleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AY6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=VOR:VORICONAZOLE'>VOR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=VOR:VORICONAZOLE'>VOR</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tl8|5tl8]], [[6ay4|6ay4]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ay6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay6 OCA], [https://pdbe.org/6ay6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ay6 RCSB], [https://www.ebi.ac.uk/pdbsum/6ay6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay6 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NF0102700 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5763 Brain eating amoeba])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ay6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay6 OCA], [http://pdbe.org/6ay6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ay6 RCSB], [http://www.ebi.ac.uk/pdbsum/6ay6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A2H4A2U9_NAEFO A0A2H4A2U9_NAEFO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Brain eating amoeba]]
[[Category: Large Structures]]
[[Category: Abagyan, R]]
[[Category: Naegleria fowleri]]
[[Category: Aksenov, A]]
[[Category: Abagyan R]]
[[Category: Calvet, C M]]
[[Category: Aksenov A]]
[[Category: Debnath, A]]
[[Category: Calvet CM]]
[[Category: Jennings, G]]
[[Category: Debnath A]]
[[Category: Luth, M]]
[[Category: Jennings G]]
[[Category: McKerrow, J H]]
[[Category: Luth M]]
[[Category: Nes, W D]]
[[Category: McKerrow JH]]
[[Category: Podust, L M]]
[[Category: Nes WD]]
[[Category: Zhou, W]]
[[Category: Podust LM]]
[[Category: Cyp51]]
[[Category: Zhou W]]
[[Category: Oxidoreductase]]
[[Category: Sterol 14alpha-demethylase]]
Retrieved from "https://proteopedia.org/6ay6"