3ah5: Difference between revisions
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==Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP== | ==Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP== | ||
<StructureSection load='3ah5' size='340' side='right' caption='[[3ah5]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='3ah5' size='340' side='right'caption='[[3ah5]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ah5]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3ah5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AH5 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ah5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ah5 OCA], [https://pdbe.org/3ah5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ah5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ah5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ah5 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/THYX_HELPY THYX_HELPY] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate. | ||
==See Also== | ==See Also== | ||
*[[Thymidylate synthase|Thymidylate synthase]] | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Helicobacter pylori]] | [[Category: Helicobacter pylori 26695]] | ||
[[Category: Hu | [[Category: Large Structures]] | ||
[[Category: Wang | [[Category: Hu Y]] | ||
[[Category: Zhang | [[Category: Wang D]] | ||
[[Category: Zhang | [[Category: Zhang J]] | ||
[[Category: Zou | [[Category: Zhang X]] | ||
[[Category: Zou Q]] | |||
Latest revision as of 15:46, 4 October 2023
Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP
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