2dtt: Difference between revisions

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[[Image:2dtt.jpg|left|200px]]


{{Structure
==Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin==
|PDB= 2dtt |SIZE=350|CAPTION= <scene name='initialview01'>2dtt</scene>, resolution 2.20&Aring;
<StructureSection load='2dtt' size='340' side='right'caption='[[2dtt]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>
<table><tr><td colspan='2'>[[2dtt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DTT FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
|GENE= PH0634 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dtt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dtt OCA], [https://pdbe.org/2dtt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dtt RCSB], [https://www.ebi.ac.uk/pdbsum/2dtt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dtt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dtt TOPSAN]</span></td></tr>
 
</table>
'''Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin'''
== Function ==
 
[https://www.uniprot.org/uniprot/O58368_PYRHO O58368_PYRHO]  
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2DTT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTT OCA].  
Check<jmol>
[[Category: Pyrococcus horikoshii]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dtt_consurf.spt"</scriptWhenChecked>
[[Category: Bagautdinov, B.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Kunishima, N.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
  </jmolCheckbox>
[[Category: H4B]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dtt ConSurf].
[[Category: 6-pyruvoyl tetrahydrobiopterin synthase (ptps)]]
<div style="clear:both"></div>
[[Category: biopterin]]
__TOC__
[[Category: national project on protein structural and functional analyse]]
</StructureSection>
[[Category: nppsfa]]
[[Category: Large Structures]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: rsgi]]
[[Category: Bagautdinov B]]
[[Category: structural genomic]]
[[Category: Kunishima N]]
[[Category: x-ray diffraction]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:31:26 2008''

Latest revision as of 08:29, 25 October 2023

Crystal structure of 6-pyruvoyl tetrahydrobiopterin synthase from Pyrococcus horikoshii OT3 complexed with (1'R,2'S)-biopterin

2dtt, resolution 2.20Å

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