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[[Image:2dze.gif|left|200px]]


{{Structure
==Crystal structure of histone chaperone Asf1 in complex with a C-terminus of histone H3==
|PDB= 2dze |SIZE=350|CAPTION= <scene name='initialview01'>2dze</scene>, resolution 1.80&Aring;
<StructureSection load='2dze' size='340' side='right'caption='[[2dze]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=PGE:TRIETHYLENE GLYCOL'>PGE</scene>
<table><tr><td colspan='2'>[[2dze]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe] and [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZE FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE= cia1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 Schizosaccharomyces pombe])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dze OCA], [https://pdbe.org/2dze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dze RCSB], [https://www.ebi.ac.uk/pdbsum/2dze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dze ProSAT], [https://www.topsan.org/Proteins/RSGI/2dze TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ASF1_SCHPO ASF1_SCHPO] Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.<ref>PMID:11856374</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/2dze_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dze ConSurf].
<div style="clear:both"></div>


'''Crystal structure of histone chaperone Asf1 in complex with a C-terminus of histone H3'''
==See Also==
 
*[[Anti-silencing factor 3D structures|Anti-silencing factor 3D structures]]
 
== References ==
==About this Structure==
<references/>
2DZE is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZE OCA].
__TOC__
[[Category: Protein complex]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Padmanabhan, B.]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Padmanabhan B]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: PGE]]
[[Category: chaperone]]
[[Category: immunoglobulin fold]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:33:23 2008''

Latest revision as of 08:32, 25 October 2023

Crystal structure of histone chaperone Asf1 in complex with a C-terminus of histone H3

2dze, resolution 1.80Å

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