2ns7: Difference between revisions

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<StructureSection load='2ns7' size='340' side='right'caption='[[2ns7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2ns7' size='340' side='right'caption='[[2ns7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ns7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NS7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NS7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ns7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NS7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NS7 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2tct|2tct]], [[1qpi|1qpi]], [[2ns8|2ns8]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tetR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ns7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ns7 OCA], [https://pdbe.org/2ns7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ns7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ns7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ns7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ns7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ns7 OCA], [https://pdbe.org/2ns7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ns7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ns7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ns7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TETR2_ECOLX TETR2_ECOLX]] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.  
[https://www.uniprot.org/uniprot/TETR2_ECOLX TETR2_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Berens, C]]
[[Category: Berens C]]
[[Category: Hillen, W]]
[[Category: Hillen W]]
[[Category: Klotzsche, M]]
[[Category: Klotzsche M]]
[[Category: Luckner, S R]]
[[Category: Luckner SR]]
[[Category: Muller, Y A]]
[[Category: Muller YA]]
[[Category: Helix-turn-helix]]
[[Category: Transcription]]
[[Category: Transcription regulator]]
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