3a6d: Difference between revisions

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==Creatininase complexed with 1-methylguanidine==
==Creatininase complexed with 1-methylguanidine==
<StructureSection load='3a6d' size='340' side='right' caption='[[3a6d]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3a6d' size='340' side='right'caption='[[3a6d]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3a6d]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A6D FirstGlance]. <br>
<table><tr><td colspan='2'>[[3a6d]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A6D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A6D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MGX:1-METHYLGUANIDINE'>MGX</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j2t|1j2t]], [[1j2u|1j2u]], [[1v7z|1v7z]], [[3a6e|3a6e]], [[3a6f|3a6f]], [[3a6g|3a6g]], [[3a6h|3a6h]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MGX:1-METHYLGUANIDINE'>MGX</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Creatininase Creatininase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.10 3.5.2.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a6d OCA], [https://pdbe.org/3a6d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a6d RCSB], [https://www.ebi.ac.uk/pdbsum/3a6d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a6d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a6d OCA], [http://pdbe.org/3a6d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a6d RCSB], [http://www.ebi.ac.uk/pdbsum/3a6d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a6d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CRNA_PSEPU CRNA_PSEPU]] Cyclic amidohydrolase that catalyzes the reversible conversion of creatinine to creatine. Is also active toward glycocyamidine, though the reaction rate is very low, but it is completely inert toward hydantoin and its derivatives.<ref>PMID:500580</ref>
[https://www.uniprot.org/uniprot/CRNA_PSEPU CRNA_PSEPU] Cyclic amidohydrolase that catalyzes the reversible conversion of creatinine to creatine. Is also active toward glycocyamidine, though the reaction rate is very low, but it is completely inert toward hydantoin and its derivatives.<ref>PMID:500580</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus fluorescens putidus flugge 1886]]
[[Category: Large Structures]]
[[Category: Creatininase]]
[[Category: Pseudomonas putida]]
[[Category: Ito, K]]
[[Category: Ito K]]
[[Category: Nakajima, Y]]
[[Category: Nakajima Y]]
[[Category: Yamashita, K]]
[[Category: Yamashita K]]
[[Category: Yoshimoto, T]]
[[Category: Yoshimoto T]]
[[Category: Closed form]]
[[Category: Creatinine amidohydrolase]]
[[Category: Hydrolase]]
[[Category: Urease-related amidohydrolase superfamily]]