3kee: Difference between revisions

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{{Seed}}
[[Image:3kee.jpg|left|200px]]


<!--
==HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435==
The line below this paragraph, containing "STRUCTURE_3kee", creates the "Structure Box" on the page.
<StructureSection load='3kee' size='340' side='right'caption='[[3kee]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3kee]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KEE FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=30B:(2R,3AR,10Z,11AS,12AR,14AR)-N-(CYCLOPROPYLSULFONYL)-2-({7-METHOXY-8-METHYL-2-[4-(1-METHYLETHYL)-1,3-THIAZOL-2-YL]QUINOLIN-4-YL}OXY)-5-METHYL-4,14-DIOXO-2,3,3A,4,5,6,7,8,9,11A,12,13,14,14A-TETRADECAHYDROCYCLOPENTA[C]CYCLOPROPA[G][1,6]DIAZACYCLOTETRADECINE-12A(1H)-CARBOXAMIDE'>30B</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3kee|  PDB=3kee  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kee OCA], [https://pdbe.org/3kee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kee RCSB], [https://www.ebi.ac.uk/pdbsum/3kee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kee ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/P90191_9HEPC P90191_9HEPC]


===HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435===
==See Also==
 
*[[Virus protease 3D structures|Virus protease 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3KEE is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEE OCA].
[[Category: Hepacivirus C]]
 
[[Category: Large Structures]]
==Reference==
[[Category: Cummings MD]]
<ref group="xtra">PMID:20166108</ref><references group="xtra"/>
[[Category: Lindberg JD]]
[[Category: Hepacivirin]]
[[Category: Nystrom S]]
[[Category: Hepatitis c virus]]
[[Category: Cummings, M D.]]
[[Category: Lindberg, J D.]]
[[Category: Nystrom, S.]]
[[Category: Hcv]]
[[Category: Hydrolase]]
[[Category: Macrocycle]]
[[Category: Noncovalent]]
[[Category: Ns3]]
[[Category: Ns4a]]
[[Category: Tmc435]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 14:07:38 2010''

Latest revision as of 16:11, 1 November 2023

HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435

3kee, resolution 2.40Å

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