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==Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain)==
==Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain)==
<StructureSection load='4jo8' size='340' side='right' caption='[[4jo8]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='4jo8' size='340' side='right'caption='[[4jo8]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4jo8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [http://en.wikipedia.org/wiki/Muhv1 Muhv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JO8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4jo8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Murid_betaherpesvirus_1 Murid betaherpesvirus 1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JO8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">m157 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10366 MUHV1]), Klra8, Ly-49h, Ly49-h, Ly49H ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jo8 OCA], [http://pdbe.org/4jo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jo8 RCSB], [http://www.ebi.ac.uk/pdbsum/4jo8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jo8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jo8 OCA], [https://pdbe.org/4jo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jo8 RCSB], [https://www.ebi.ac.uk/pdbsum/4jo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jo8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KLRA8_MOUSE KLRA8_MOUSE]] Receptor on natural killer (NK) cells for class I MHC.
[https://www.uniprot.org/uniprot/Q6XK91_MUHV1 Q6XK91_MUHV1]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Muhv1]]
[[Category: Murid betaherpesvirus 1]]
[[Category: Beddoe, T]]
[[Category: Mus musculus]]
[[Category: Berry, R]]
[[Category: Beddoe T]]
[[Category: Brooks, A G]]
[[Category: Berry R]]
[[Category: Call, M J]]
[[Category: Brooks AG]]
[[Category: Corbett, A J]]
[[Category: Call MJ]]
[[Category: Coudert, J D]]
[[Category: Corbett AJ]]
[[Category: Degli-Esposti, M A]]
[[Category: Coudert JD]]
[[Category: Deuss, F A]]
[[Category: Degli-Esposti MA]]
[[Category: Forbes, C A]]
[[Category: Deuss FA]]
[[Category: Lin, J]]
[[Category: Forbes CA]]
[[Category: McAlister, A D]]
[[Category: Lin J]]
[[Category: Ng, N]]
[[Category: McAlister AD]]
[[Category: Perugini, M A]]
[[Category: Ng N]]
[[Category: Rossjohn, J]]
[[Category: Perugini MA]]
[[Category: Saunders, P M]]
[[Category: Rossjohn J]]
[[Category: Scalzo, A A]]
[[Category: Saunders PM]]
[[Category: Sullivan, L C]]
[[Category: Scalzo AA]]
[[Category: Vivian, J P]]
[[Category: Sullivan LC]]
[[Category: Widjaja, J M]]
[[Category: Vivian JP]]
[[Category: C-type lectin-like domain]]
[[Category: Widjaja JM]]
[[Category: Immune system-viral protein complex]]
[[Category: Natural killer receptor]]
[[Category: Viral immunoevasin]]
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